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Doctor insights on: How Is A Bone Marrow Match Determined

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Emily Lu Dr. Lu
5 doctors agreed:
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How is a bone marrow match determined?

Emily Lu Dr. Lu
5 doctors agreed:
How is a bone marrow match determined?

HLA type: Every cell in your body has human leukocyte antigens (hlas) on the surface that act like a cell i.D. These allow your immune cells to recognize your cells as part of you and not foreign cells that need to be attacked. The bone marrow donor's hlas should match the patient's hlas as closely as possible so the donor's immune system doesn't attack the patient! hla is determined by a blood test. ...Read more

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Bone Marrow (Definition)

Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more


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How could a bone marrow match be determined and what is the procedure?

How could a bone marrow match be determined and what is the procedure?

It requires Tissue t: It requires fairly sophisticated lab tests to do the tissue typing and matching between the donor cells and the recipient. It is called hla(human leukocyte antigen) typing which is done from body cells(usually taken from a cheek swab) of the donor. Blood cells(white cells) are a common cell type used as the tissue antigens/proteins are commonly expressed on the white cells. ...Read more

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There's a friend baby that needs a bone marrow match he has cancer? What is a bone marrow and can one person life without it I would like to donate

There's a friend baby that needs a bone marrow match he has cancer? What is a bone marrow and can one person life without it  I would like to donate

Bone marrow transpla: You need to read up about Bone marrow transplants and about Blood stem cells. There is ample information on the Google. Also read up about " Be the Match" and check on national marrow Donor Program(NMDP). This will answer all your questions about being a Donor for Bone marrow transplantation in the child in question. Let us know after you have done some reading and learn the details. ...Read more

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What are the chances I would/could be a bone marrow match for a family member ie father, brother, daughter etc?

What are the chances I would/could be a bone marrow match for a family member ie father, brother, daughter etc?

Pretty good.: Family members usually have a pretty good to be a good match. But with the availability of Bone marrow registry, its also easy to find a find out in the community. If someone needs a bone marrow transplant, the physician will look for the best match available in the family & the community. The final decision is based upon the patients medical condition, health status & donor availability. ...Read more

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How to find out if your a bone marrow match to.Someone. How do they do the bone marraow transplant for donor and one who.Needs it?

How to find out if your a bone marrow match to.Someone. How do they do the bone marraow transplant for donor and one who.Needs it?

It is simple process: You can get this information on the internet by looking up: 'be the match'. Your local blood bank can also give you literature in case you do not have access to the internet. You can be a donor by volunteering, giving a sample of your inner cheek cells(they take a swab) and enter your data in the marrow bank, then call you when your cells match with a needy person. ...Read more

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What's the probability of me being a match for donating bone marrow?

It depends: Chances of you being a match are low but real. So be prepared to keep your commitment in case you receive a call to be the real donor because they have someone whose hla typing matches yours...The chances are less than one in a thousand unless you are blood related with the donor. ...Read more

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How likely would I be matched to donate bone marrow?

How likely would I be matched to donate bone marrow?

Depends: On average, about 1 in 500 registry member will go on to donate bone marrow to a patient. Because of the variety in tissue types, it's difficult to predict an individual's chance of being able to donate. http://bethematch.org/ ...Read more

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How would i determine if i'm a match to donate bone marrow anonymously?

Awesome gesture!: That's a great and noble gesture! go to your local hospital and ask to join up to the national bone marrow database. It should be a quick exam and test to collect data on you, you have the option of remaining anonymous. This is great and i hope more people follow your lead! if this helped, please vote or follow me, thanks and best of luck! ...Read more

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What do you advise if I'm seriously considering to become a bone-marrow donor. what "factors" need to match?

What do you advise if I'm seriously considering to become a bone-marrow donor. what "factors" need to match?

HLA-matching: Human Leukocyte Antigen ( HLA) is a kind of tissue typing (tested from the blood white cells or buccal swab cells) that is used in matching patient and donor for bone marrow transplantation. Identical twins have essentially the same HLA type. Siblings from the same set of parents have a better chance of matching than other relatives. Unrelated donors can be found for a majority of Caucasians. ...Read more

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How would I determine if my family members are a match for bone marrow transplant?

How would I determine if my family members are a match for bone marrow transplant?

Blood test: Matching involves typing human leukocyte antigen (hla) tissue. The antigens on the surface of these special white blood cells determine the genetic make-up of a person's immune system. There are at least 100 hla antigens; however, it is believed that there are a few major antigens that determine whether a donor and recipient match. The others are considered "minor" and their effect on a successful. ...Read more

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A match for bone marrow transplant? A distant relative needs a bone marrow transplant. How can I find out if i'd be a match?

Short answer: Hla. Human leukocyte antigens (hla) are proteins — or markers — found on most cells in your body. Your immune system uses these markers to recognize which cells belong in your body and which do not. A close hla match between patient and donor is the most important factor in selecting the best bone marrow donor for a patient. ...Read more

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What has to match between a donor and recipient for a bone marrow transplant to be successful?

Tissue type: The tissue type of the recipient and donor must match. This is a measurement of the hla type which looks at proteins on the surface of our cells that help the immune system recognize 'self' verus 'non-self.'. ...Read more

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What exactly does it mean to have a match between a donor and receipitant for a bone marrow transplant to be sucessful?

The Tissue types: There is a tissue match called hla matching which is done to check and match your tissue types with the receving person's tissue type. ...Read more

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What do you suggest if my mother has plasma cell leukaemia and there is no bone marrow match for her has she any chance?

What do you suggest if my mother has plasma cell leukaemia and there is no bone marrow match for her has she any chance?

See expert: Your mother should be seen at a major academic center if she has not already (she may have been for the bone marrow transplant consultation). This is a question you should be asking someone who does nothing but myeloma or plasma cell disorders. Be honest and frank about your concerns with her doctor. Make sure your mother is okay with you discussing this. ...Read more

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My mother has plasma cell leukaemia and there is no bone marrow match for her. Does she have any other chance of survival>?

My mother has plasma cell leukaemia and there is no bone marrow match for her. Does she have any other chance of survival>?

Find a Myeloma exper: There are a dozen of experts who can treat her myeloma. Seek one of them to guide you. There are many good drugs that can be useful unless she has used them up already. There are some experimntal drugs too. So go see Dr Sunder jagannath at Mt Sinai or go to Mayo clinic in Rochester Minnesotta. ...Read more

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My father died about 5 years ago from multiple myeloma. I was the bone marrow donor for his transplant. I am an only child and am wondering about my risk factor for myeloma, especially since my marrow was considered a good match.

NCI Study...: An nci study is looking at characterizing families that may be at higher risk to identify causes: screening individuals and families at high risk for hematologic cancers nct00052234 http://clinicaltrials.Gov/ct2/show/nct00052234?Term=nct00052234&rank=1. ...Read more

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Bone (Definition)

Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more