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How Is A Baby Born With The Sickle Cell Trait When Neither Parents Has It
New mutation: Sickle cell trait is almost always caused by a gene passed down from one parent. The parent may not even know he or she has it. Rarely, a new mutation can also occur-- a child's gene changes on its own, meaning that they didn't get it from a parent. I could not find the exact rate of these new mutations. It's rare, but it can at least theoretically happen. ...Read moreSee 1 more doctor answer
An inherited blood disease causing red blood cells to be sickle (curved) shaped instead of round. It shortens life expectancy, and can result in bacterial infections, painful swelling of the hands and feet, fever, arthritis, leg ulcers, fatigue, anemia, eye damage, and ...Read more
If one parent has the sickle cell trait and the other is normal, is it possible that their child can get the sickle disease?
My son has the sickle cell trait and neither his father or me have the trait. This is confirmed. How is this possible please?
New mutation: i am going to assume that a real lab study has confirmed this by hemoglobin electrophoresis and this is not a sample switch, tech error, or other cause of a bad result. Since Junior is going to ask questions, I would urge for the family's sake to do the genetic studies to confirm paternity. You are brave to ask. Best wishes. ...Read more
Is it genetically possible for a parent with sickle cell disease to have a baby without sickle trait?
Only using a donor: The offspring of someone with ss disease wil either have trait, or if the spouse has other issues could have trait plus whatever is contributed by the spouse. If the spouse has trait, ss or trait are the potential outcomes. If the baby has none of the genes of the ss parent (thru ivf etc.) they could escape the gene. ...Read more
Needs special care: Baby w/ sickle cell disease needs special attention, so work closely with your pediatrician and pediatric hematologist (blood disease specialist). Your baby need daily medications (vitamins, antibiotic). You need to learn to spot signs and symptoms of sickle cell crisis. Your infant should get all routine childhood vaccines because he/she may not be able to fight infections well. ...Read more
If my baby is born with sickle cell disease does that mean I and her father have to have the trait?
Yes: Both of you have to carry the gene. ...Read more
What it the probability that a couple's child will be afflicted with sickle cell anemia if they both carry that trait but don't exhibit it?
Highly unlikely...: It is theoretically possible for someone to acquire a new mutation (de novo mutation) that is not inherited from a parent, but this has not been described for the sickle cell mutation. Statistically speaking, if you have sickle cell trait, one your biological parents also has to have it. ...Read moreSee 1 more doctor answer
When a child is born with extra chromosomes is that a genetic trait from the father side or the mother side? Or can it go both ways?
Both but not a trait: During formation of either egg or sperm (gametes), the chromosome (c) pairs that make up the normal cell separate & each gamete is supposed to have 1/2 of a pair. If any pair does not separate, three rather than a pair of that c be in the embryo. Having an extra c in every cell of the fetus confuses development.Miscarriage or birth defects often occur.This is not a trait but an error in whole cms. ...Read moreSee 1 more doctor answer
I have a friend who is a carrier of thalassemia. The girl he intends to marry is also a carrier. Does this mean they can't have children?
Not infertile: But they have 25% chance that any child will have full blown thalassemia major which is devastating, 50% that child will also be carrier & only 25% child will be thalassemia major or carrier free. They have as much chance of having children as any other couple, but is it worth it? ...Read moreSee 2 more doctor answers
Will a colorblind woman always have colorblind children? I know the cause is a mutation on the x-chromosome and a woman has to have the mutation on both her x’s. So that means all her children will have the colorblind gene. So will her children all be col
Her : Her male children will be colorblind because all of her male children will have one of her x's with the colorblindness gene and a y from the dad that cannot cancel out the colorblindness gene on her x. If she has children with a man who is not colorblind than her daughters will carry the gene, but not be colorblind themselves since they'll have a normal x from their dad to cancel out their mom's x with the colorblindness gene. If she has children with a man who is colorblind, then her daughters will be colorblind also. This is why colorblindness is much more common in men than in women. Legal disclaimer: I am providing this general and basic information as a public service and my response to this question does not constitute a doctor-patient relationship. For any additional information, advice, or specific concerns, please speak with your own physician. The information provided is current as of the date of the answer entry. ...Read moreSee 1 more doctor answer
Talesemia is genetic blood deasease, what the chances of my children to get talesemia if their mother is a carrier and i'm not?
Could be carriers: Carriers have one normal paired with one carrier (altered) gene.During the formation, there is 50% chance that either will make it into the egg.When paired with your normal gene at conception you have those two possibilities.So with every pregnancy , you have equal risk of producing a carrier child or one with normal genes. ...Read more
What are the odds that a child will have sickle-cell disease if her father has the disease while her mother does not?
Depends: If mom is not a carrier, all the kids will just be carriers.(none with SS disease) If mom is a carrier, there would be a 50% chance that any baby would have sickle cell. ...Read more
No: Sickle cell trait means that one is a "carrier" of the sickle cell gene. It takes two copies of the sickle cell gene to manifest sickle cell disease. If a man has sickle cell trait, he may pass the sickle cell gene or the normal gene to his offspring - meaning 50% risk that he will pass on the sickle cell gene. The offspring's chance of inheritance also depends on the status of the mother! ...Read more
If one parent has beta thalassemia, what are the chances that their baby could inherit the condition?
Depends: If one parent has beta thalassemia major, and the other parent has none, then their children should all be carriers. If the other parent is a carrier then about half their children will be carriers and half have disease. If one parent has beta thal minor (carrier), and the other parent has none, then about half their children will be carriers and half will be normal. A geneticist can give details. ...Read moreSee 1 more doctor answer
Two possibilities: There will always be two possibilities in the offspring of a trait carrier.They can pass on the sickle trait in one of the 2 possible genes, or pass the normal gene.He could have all his kids carry trait, or none or some.You basically flip a coin every conception to see which comes up. ...Read moreSee 2 more doctor answers
Unlikely: A person is born with a genetic condition either because they inherit it or they experience what is called a "mutation". Being born with sickle cell anemia means one has two hemoglobin genes with the same mutation. Spontaneous sickle mutations are thought to occur extremely rarely, so virtually all babies with ssa inherit an abnormal gene from both parents. ...Read moreSee 1 more doctor answer
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