Doctor insights on:
Rate Of Leukemia Development
Why does leukemia come on so fast my daughter was diagnosed on a friday and five days later died she was 8 yrs old and had aml leukemia m4
A malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more
Anyone...: Can get leukemia. Rarely some individuals might inherit a familial disposition, and a few occupational exposures may increase risk (radiation or benzene exposure). More often it occurs from a series of random mutations that happens by bad luck in a single bone marrow stem cell. These mutations causes it to increase in number dramatically, pushing out healthy cells, but leaves them under developed. ...Read more
Leukemia cause: We don't know for sure. Leukemia develops as the consequence of a series of genetic changes in blood cell offsprings. These changes alter normal growth and differentiation of the cells, resulting in an accumulation of abnormal, immature blood cells in the bone marrow and peripheral blood. Exposure to chemicals, radiation, tobacco, or chemotherapy, infection, etc have been associated with leukemia. ...Read more
No necessarily: Long time ago that was true. But the modern treatments for leukemias are quite effective and are often curative. But the treatment is best done at a cancer center where you can find experienced leukemia specialists especially if it is an acute leukemia (as opposed to chronic leukemias which are less serious and easier to treat). ...Read more
Taste changes: When you are not feeling well (having leukemia) etc - you can have some alteration of the sense of tase. In addition distortion of the sense of taste (dysgeusia) can be also caused by other things like drugs- eg. Antibiotics, asthma treatment, chemotherapy, zinc deficiency etc. ...Read more
Drugs +/- radiation: Various chemotherapy drugs and new targeted therapies are used that preferentially kill cancer cells while minimizing side effects. Sometimes radiation is used alone or in addition to drugs depending on the type and stage of cancer. This is a discussion you will have with your cancer team during which you should have ample opportunity to ask questions. Take a pad and paper with you. ...Read more
No such condition!: Leukemia by definition is a name given to blood cancer. But there are at least 4 separate types of Leukemias, broadly classified as Acute Leukemias (a very serious disease requiring immediate treatment) and Chronic Leukemias (which are slowly growing Cancers and have a much better prognosis as people with Chronic leukemia can survive for many years...some of these patients are cured with medicines. ...Read more
CBCj, flow cytometry: Leukemia is suspected when abnormal cells our found in the blood, or when blood counts are very low. The first test is the CBC (complete blood count). If abnormal cells are in the blood, they can be identified by flow cytometry, which analyzes compounds on the surface of blood cells. The definitive test otherwise is a bone marrow aspirate and biopsy, usually taken from the pelvic bone. ...Read more
Blood or bone marrow: Typically this s diagnosed by a bone marrow test. In the marrow will be the abnormal proliferation of cells of the same type. At times, these cells in the can "spill" into the blood. When this occurs, the leukemia s diagnosed on blood tests. Even when noticed in the blood, a marrow test is usually performed as well. ...Read more
See below...: Yes, a staging system is used for many types of cancer including leukemia; however, the factors involved are numerous and staging also depends heavily on the specific type of leukemia. Therefore, the staging for each particular case should be performed under the guidance of a hematologist/oncologist. ...Read more
No one knows: Only in rare circumstances do we actually know the cause. Those times would be if the child was previously treated with chemotherapy or radiation therapy, if there is a known genetic problem like down's syndrome or in a few families where it may be hereditary. Exposures, foods, cellphones, high voltage transmission towers, etc have not been proven to increase the risk of getting leukemia. ...Read more
Very briefly: Leukemia is a form of blood and bone marrow cancer. Some forms can be cured and some not. The outcome depends heavily on the type of leukemia, age of the patient, previous state of health, genetic abnormalities, and many other factors. The initial signs and symptoms may be very nonspecific and therefore, if a concern for leukemia exists, consultation with a physician is recommended. ...Read more
Multiple: Leukemia can present with multiple signs and symptoms including but not limited to: bone pain, refusal to bear weight, gum bleeding, bleeding from other sites, pallor, lack of appetite, fever, night sweats, unexplained weight loss, easy bruising, fatigue, etc. If a concern for leukemia exists the diagnosis is confirmed with blood and bone marrow tests. ...Read more
Many things: These can increase your risk, but do not mean you will get leukemia: 1. Family history of leukemia 2. Exposure to certain chemicals, eg benzene (found in degreasers) 3. Exposure to high or chronic radiation eg nuclear reactors 4. Previous chemotherapy or radiation therapy 5. Myelodysplastic syndrome 6. Downs syndrome and other genetic diseases 7. Smoking! ...Read more
Four categories...: They are acute myeloid or acute lymphoid leukemia (aml and all), and chronic myeloid or chronic lymphoid leukemia (cml and cll). However, there are variants within each of these categories that reflect their unique molecular natures. The categories simply reflect the expression of markers of differentiation along each of these lineages and the ability to mature. More specific info if you wish. ...Read more
Depends on type of l: There are 4 different types of leukemia, so we need to know what type of leukemia are you interested in knowing about? There is definitely a chance of dying from leukemia but there is also curative treatment available for many patients with leukemia. So you need to ask this question to your treating doctor. ...Read more
Nothing: I do not know of anything that can prevent leukemia. A study at mayo clinic by dr. Shanafelt was looking at treating early stage cll with green tea extract. Further studies will likely go forward. Some risk factors, such as prior chemotherapy for other cancers can increase the risk of leukemia, but that is likely not avoidable. I am unaware of any diet or exercise intervention. ...Read more
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