Doctor insights on:
How Effective Is Pep
No percentage can be given that's accurate since the data on it is limited.
So I recommend taking it if there is any doubt in exposure. ...Read more
How effective is PEP (post exposure prophylaxis) medication? I have read that old mono-therapies were around 80% effective. What about new treatments?
Very effective: There are no research studies to document the actual effectiveness of PEP. (It would be ethically impossible to research this by giving some people real PEP and comparing to untreated people on placebo.) Based on animal research and clinical experience, current multi-drug PEP is believed to be nearly 100% effective if started promptly. Effectiveness is less certain after 24-48 hours ...Read more
How effective is HIV PEP if started within 2 hours and transmitting person had a viral load of 40 copies/ml? Is PEP a myth? Percentage that it works?
PEP works, low risk: Post exposure prophylaxis (PEP) is not a myth. It works. However, there are no data on exact effectiveness for various kinds of exposure or at different viral loads. With an HIV viral load of 40, transmission of the virus is unlikely even with a high risk exposure. If you also take PEP starting as soon as 2 hours, it is extremely unlikely you will be infected. ...Read more
Is viread+emtriva effective as a pep course 60 hours after possible exposure? How should they be taken together? Thank you
A small cat bit me 8 months ago for which I took pep vaccinations just now, can they still be effective? I am worried about rabies too much, plz help
Which vaccines?: I am not sure what you mean by pep vaccines? I think you mean "pet vaccines" Which ones were included? If you recently received rabies vaccination, your risk of rabies is greatly reduced. If the cat bite was 8 months ago, it is highly unlikely you will contract rabies from that bite now! ...Read more
What permanent damage can a 28 day PEP course of Tenofovir (+ Fumarate + Emtricitabine) do to one's body? Also, how effective would the said combination of drugs be in preventing HIV after 68 hours?
Damage is unlikely: It is most effective when started within 72 hours. Nausea, vomiting, and diarrhea are the most likely short-term side effects. Long-term side effects are not expected. Tenofovir may strain the kidneys or liver - usually in those with kidney disease or hepatitis already - but permanent damage is rare. The risks of long-term organ damage are much more likely from the HIV virus than from this drug ...Read more
Subsequent to a rabid dog bite my 8 yr old son, on the same day he had taken pep. Is it 100% effective against rabies?
Great but...: In my experience, nothing is 100% guaranteed. All the best. ...Read more
How doctors explain the long incubation period (>1 year) of rabies, can pep vaccination still be effective after 9 months of possible exposure?
Rabies is tricky: Rabies is known for a wide variation in the incubation period. The average is 3 weeks to 3 months for infection to take hold. About 5% of cases occur 1 year after exposure. The longest case on record is 19 years. Experts don't know exactly why this is-but it probably has to do with the virus strain, other viral properties, the patient (how strong their immune system is) etc. YES-I agree with PEP! ...Read more
Phlegm: There are no studies on pepper tree leaves. You might consider using an over the counter mucolytic instead. ...Read more
BP: I wouldn't consider those leaves an effective treatment ...Read more
Not: Any observed effect is likely to be coincidence. ...Read more
Natural supplements: Some people believe they get a benefit from using a natural product such as pepper tree leaves. Certainly our ancestors before modern medicine believed in this and there are many cultures using many, many plant based compounds that could have an effect. This is the field of ethanobotany. Some of the approaches of traditional medicinal yield modern day results -such as aspirin, anti-malarials etc. ...Read more
Prevention of hiv: One can be infected by HIV if stuck by an infected needle; however studies have shown that if highly active anti-retroviral (haart)medication is taken within 36 hours of exposure to the HIV virus through needle stick and/or body fluid or any bloody fluid, the risk of contracting the disease is dramatically decrease when haart is taken as prophilaxis (prevention). ...Read more
Non-immune: If you've had close contact with someone with hepatitis a and you're not immune (either through vaccination or prior infection), you should receive Immune Globulin and start the vaccine series. Better yet, just get vaccinated so you won't ever have to worry about being exposed. ...Read more
Triple Cocktail: Nope. This is not a pep appropriate treatment. ...Read more
Do follow up testing need for exposure person after pep if the source person is HIV rapid test and HIV duo test negative?
No: You don't need pep, or follow-up testing, after exposure to an hiv-negative person. ...Read more
I had a 4th Gen HIV combo test done 9 weeks post exposure and 5 weeks after completion of PEP. Is this conclusive? Tqvm.
Yes and no: Its conclusive for now. But your not done. Tests like this that measure antibodies have to be repeated up to 6 months to ensure 99% that your in the clear. ...Read more
How long does a delusional state last from smoking pep spice? Is there anything that can enhance recovery and stabilization?
Don't know: "pep spice" is extremely dangerous -- it consists of unidentified herbs & spices sprayed with a synthetic thc-like substance in unmeasured quantity. It produces a feeling of being stoned ['delusional"]. When you don't know the particular contents or amount, you also don't know "how long" this state will last -- or how best to enhance recovery or stabilization. My best advice is to steer clear! ...Read more
If you don't get post exposure pep for rabies untill 12 days after the possible exposure what are the chances of it working?
Is weight gain possible on PEP? I gained 2-3 pounds while on PEP and weighted 147. Once I got off, I dropped back down to 144.
If a person was bitten by a cat/dog and that animal is alive for 20days after that bite, will that person get rabies? Does he need to get rabies PEP?
Too late: If you waited that long after exposure it would be too late to benefit from rabies shots. If the animal had no symptoms by that point, the animal did not have rabies. Those whose lifestyle place them at risk for rabies exposure (animal control, living in endemic areas) can get the vaccine ahead of time and be protected for at least 2 years from any exposure. ...Read more
I had negative results in 3rd gen rapid test and HIV duo 4th gen test 4weeks after pep completion and 7 weeks after exposure. How reliable are these?
Started pep after 9 weeks of exposer. Will it affect to detect HIV after 3 months of exposer if HIV transmitted? (result were negative on 8 & 10 weeks)
Negative HIV duo and 3rd gen. 7 weeks after exposure. But 3 weeks after pep. What are my chances of being infected?
Small: Negative testing after 7 weeks is a good sign, so the chance of infection is very low. You may wish to have one more test at 12 weeks to verify negative status. ...Read more