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Doctor insights on: How Does Tegretol Affect The Brain

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Dr. Mohamad Mikati
433 doctors shared insights

Carbamazepine (Definition)

This drug was once the breakthrough product to treat trigeminal neuralgia, and later various forms of epilepsy, and even psychiatric uses ...Read more


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I had a brain surgery last july and i used zyprexa (olanzapine) and tegretol daily until this january.I gained a lot of weight. Will i lose weight as im off meds?

I had a brain surgery last july and i used zyprexa (olanzapine) and tegretol daily until this january.I gained a lot of weight. Will i lose weight as im off meds?

You could: You could lose weight when off these medicines, especially if you increase your exercise and attend to a healthy food plan. Talk with your doctors about this; they'll likely have more personalized recommendations for you than we're able to provide without knowing you. Good luck to you. ...Read more

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In de novo epilepsy (age 67) MRI shows signs of slightly poor brain circulation. Is medication for circulation advised? The patient is now on TEGRETOL

In de novo epilepsy (age 67) MRI shows signs of slightly poor brain circulation. Is medication for circulation advised? The patient is now on TEGRETOL

Brain circulaton-sz: Why poor circulation ? ischemia (from clogged vessels)? hypoplastic vessels ( born with small vessels? carotids? Did MRI show stroke? Do they have a fib? was the seizure due to stroke/ TIA ( rare)? has the doctor discussed aspirin 81 mg or plavix (clopidogrel) or plental or fish oil ( blood thinners so may cause bleeding) ? f/u and discuss w/neurology http://www.ncbi.nlm.nih.gov/pubmed/11286042 ...Read more

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Geriatric epilepsy unknown etiology patient on TEGRETOL . Short memory loss and signs of poor brain circulation(MRI), drugs advised?Cavinton ?

Geriatric epilepsy unknown etiology patient on TEGRETOL . Short memory loss and signs of poor brain circulation(MRI), drugs advised?Cavinton ?

Cerebral blood flow: Carbamazepine is a good agent for seizures, but can be associated with cognitive side effects. If the issue is with blood flow in brain, additional details need to be provided. As for Vinpocetine (Cavinton) there is anecdotal evidence of improvement of blood flow, but there is less experience with that drug in regulated markets (eg US FDA) to comment on usage. ...Read more

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68 yr-old man, new-onset loss of left toes dorsiflexion, 51 years after Harvey Cushing's Osteoplastic Craniotomy for temporal lobe epilepsy.....?

68 yr-old man, new-onset loss of left toes dorsiflexion, 51 years after Harvey Cushing's Osteoplastic Craniotomy for temporal lobe epilepsy.....?

See ur NeuroSurgeon: New-onset loss of L foot dorsiflexion after craniotomy may be a complication of surgery, perhaps related to positioning. EMG/NCV (muscle & nerve testing) can localize site of nerve injury. Physical therapist can offer exercises to improve function as well as recommend ankle-foot orthotic to minimize risk of falling/tripping due to foot drop. Bottom line, chat w/your NeuroSurgeon then see FamilyDoc ...Read more

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How long would it take for a steady state concentration from 100mg of lamictal to 50 mg--keeping in mind i also take 600 mg of tegretol.

How long would it take for a steady state concentration from 100mg of lamictal to 50 mg--keeping in mind i also take 600 mg of tegretol.

Probably 2-3 days: Since the half-life of Lamictal is ordinarily about 33 hours (presuming normal kidney function) and the elimination half-life is decreased significantly by the presence of tegretol that speeds lamictal's metabolism, i think it should only take 2 to 3 days to reach steady state on 50 mg daily after having previously been on 100 mg daily. ...Read more

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Would 1 mg of ativan be about equal to 1 mg of klonopin (clonazepam)..Keeping in mind the klonopin (clonazepam) is lowered by 600mg of tegretol by about 30%?

Would 1 mg of ativan be about equal to 1 mg of klonopin (clonazepam)..Keeping in mind the klonopin (clonazepam) is lowered by 600mg of tegretol by about 30%?

Longer duration: Klonopin (clonazepam) has a much longer effect than Ativan although i feel the tranquilizing effects are comparable. However different people react in differing ways to these 2 tranquilizers. ...Read more

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Does nocturnal temporal lobe epilepsy disappear? I have no seizures since 7 years. The seizures were 40 seconds long. I've always taken carbamazepine.

Does nocturnal temporal lobe epilepsy disappear? I have no seizures since 7 years.
The seizures were 40 seconds long. I've always taken carbamazepine.

Can: Most large studies of withdrawing seizure medicines were done at the 2 yr seizure-free mark. Evaluation by a neurologist can help evaluate the risk of tapering off. Eeg and MRI along with the history and exam help determine chances of success. If it's the genetic nocturnal tle, then recurrence would be likely off aeds. ...Read more

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Sometimes i forget my medications amlodopine (for hypertension) & carbamazepine (for temporal lobe epilepsy). Can i go without them like this?

Sometimes i forget my medications amlodopine  (for hypertension) & carbamazepine (for temporal lobe epilepsy). Can i go without them like this?

Medications: Medicines are tested for effectiveness usually with one primary dosage methodology. If you want the outcome associated with the proof of effectiveness; you need to take the medication as it is approved and prescribed. If you don't take them as prescribed, your chances of the desired outcome are impaired. ...Read more

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Hv left temporal lobe epilepsy, on 150 mg lamictal x 2 times, tegretol 200 mg x 2 times. What are consequences of tegretol taken for over 30 yrs?

Hv left temporal lobe epilepsy, on 150 mg lamictal x 2 times, tegretol 200 mg x 2 times. What are consequences of tegretol taken for over 30 yrs?

Probably minor: Although tegretol rarely caused bone marrow suppression and liver abnormalities, the most likely long-term effects include low sodium, mild liver function abnormalities, elevation of cholesterol levels, and osteoporosis. ...Read more