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Doctor insights on: How Does Septicemia Lead To Multi Organ Failure

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How does septicemia lead to multi organ failure?

How does septicemia lead to multi organ failure?

Toxins in blood: When you get septicemia, it causes a severe and overwhelming inflammatory reaction. Unfortunately, the same inflammatory chemicals can cause damage to other organs, such as the lungs, the kidneys, the heart, and other organs. That is how you can get multi-organ failure. ...Read more

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Dr. William Walsh
1,880 doctors shared insights

Sepsis (Definition)

The body's abnormal response to severe infection. Sepsis symptoms include fever, rapid heart rate and rapid breathing, and bloodwork will reveal elevation of ...Read more


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Please tell me if there are any diseases that cause multiple organ failure that won't show up in normal blood work?

Please tell me if there are any diseases that cause multiple organ failure that won't show up in normal blood work?

Won't need labs: Multiple organ failure is obvious on history and physical exam. Subtle illnesses that routine labs won't spot include the porphyrias, Addison's, chronic carbon monoxide, pheo, parasomnias, Crohn's, syphilis, Lyme, arsenic (any enemies?), lupus, some myopathies & vasculitides, sleep apnea, some nutritional deficiencies, early celiac sprue, Simmonds', others. ...Read more

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What is a typical timeline from injury to neurogenic shock to death? Do shock symptoms ever present and then go away until multiple organ failure?

What is a typical timeline from injury to neurogenic shock to death?  Do shock symptoms ever present and then go away until multiple organ failure?

Timeline from: Insult or injury to shock and death or recovery depends on various factors including the physical condition of the individual and contributing factors - presence or absence of hypertension, diabetes , kidney / heart problems etc. It may be from hours to days. Recovery is possible if the body responds to treatment. God bless u! ...Read more

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Hi doctors, can you tell me what is multiple organ failure?

Hi doctors, can you tell me what is multiple organ failure?

It is not good: When an organ such as the liver fails due to disease, it can cause kidney, heart and other digestive organs to fail also, ergo muliorgan failure. ...Read more

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Help docs! i'm trying to find out what causes multiple organ failure?

Help docs! i'm trying to find out what causes multiple organ failure?

Low blood supply: Low blood supply to the body will cause all organs to malfunction and fail if not corrected. Low blood supply can be caused by heart failure, low blood volume (bleeding, dehydration) and overwhelming infection, among others. ...Read more

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Can "lidocaine" affect the multiple organ failure of a severe dka {100mmol/l} with glasgow score of 4/15?

Can "lidocaine" affect the multiple organ failure of a severe dka {100mmol/l} with glasgow score of 4/15?

Unlikely: Of course it is important to know the dose and the route of the administration, but if you are talking about about severe diabetic ketoacidosis, therapeutic use of Lidocaine should not worsen multiorgan failure, to my opinion. ...Read more

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Could pneumovax vaccine also prevent multiple organ failure?

Could pneumovax vaccine also prevent multiple organ failure?

Hard to say early on: The vaccine will help the recipient develop resistance to many strains of pneumococcus germs. It is plausible that it might prevent an infection that could become deadly and cause such failures. By itself, the vaccine simply promotes good health, it is not a magic potion. ...Read more

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Can a bacterial infection in the gallbladder cause multiple organ failure?

Can a bacterial infection in the gallbladder cause multiple organ failure?

Sepsis: If you develop systemic infection (sepsis), then definitely yes. This is called ascending cholangitis and can be very serious and life threatening. ...Read more

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Could a bacterial infection in the gall bladder cause multiple organ failure?

Could a bacterial infection in the gall bladder cause multiple organ failure?

Severe infection: Where in body can cause multiple system failure. It depends on the location and severity of infection, type of organism causing the infection, host response to infection, and how rapidly effective treatment of infection can proceed. ...Read more

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Would it be possible that a bacterial infection in the gall bladder cause multiple organ failure?

Would it be possible that a bacterial infection in the gall bladder cause multiple organ failure?

Overwhelming: Septicemia in any organ cause multiple organ failure. It is rare for acute cholecystitis alone to cause multiple organ failure, unless there are co-morbid conditions such as malignancy, diabetes, hiv, liver disease or kidney failure, but these are general statements, so ask your doctor for specific advice. ...Read more

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Narcotic pneumonia 6yrs ago. Multi organ failure septic shock. Bronchoscopy done everything normal. Cough up mucus still and get breathless. ?

Narcotic pneumonia 6yrs ago. Multi organ failure septic shock. Bronchoscopy done everything normal. Cough up mucus still and get breathless. ?

Mgt: The severity of your pneumonia was significant and can lead to changes of airway structure. One possible diagnosis is bronchiectasis. I would suggest a sputum culture and TB skin test, in addition to a HRCT of your chest to evaluate. A virtual appointment is also available for further details and to review uploaded results. ...Read more

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What is the chances that my child's infection will lead to septicemia?

Depends: It depends on the infection location, bacterium (or virus or fungus), the age of your child, and how healthy your child's immune system is. In general, for most children and most infections, it is highly unlikely that they will develop sepsis. ...Read more

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Can a bad bedsore lead to sepsis or septicemia?

Can a bad bedsore lead to sepsis or septicemia?

Yes: Any wound can be a portal for bacteria or other pathogens (fungus), so a bedsore can certainly become infected and the patient can become quite ill, develop septic shock and die or develop associated osteomyelitis (bone infection). Generally these are treated locally and develop no complications. ...Read more

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Can toe infections lead to blood poisoning in diabetic?

Can toe infections lead to blood poisoning in diabetic?

Yes: I think by blood poisoning you are referring to septicemia. Diabetics usually have worse infections than a non diabetic so they are more susceptible to a worse infectious process particularly if they are uncontrolled diabetics or if they 'didn't seek treatment right away because of not knowing they had a problem due to neuropathy. It is possible but not common. ...Read more

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What organ systems are more likely to get sepsis?

What organ systems are more likely to get sepsis?

Depends: Sepsis is your body's generalized inflammatory response to an infection somewhere. What organ systems are affected depend a bit on your medical conditions and depend a lot on where the infection starts. For instance, pneumonia that leads to sepsis will definitely affect your lungs first. In general, the organ systems most commonly affected by sepsis are your kidneys, your lungs, and your heart. ...Read more

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I have a donated organ, will sepsis cause complications?

I have a donated organ, will sepsis cause complications?

Yes: Especially since your immune system is compromised. Also depends on what organ you have donated. Kidneys are at risk from low blood pressure. ...Read more

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Is sepsis common with people that have organ transplants?

No: Sepsis meaning infection in the blood can occur in any surgical patient; and certainly immunosuppressed transplant recipients, but it is not common. It can derive from tubes, drains, IV sites, the lungs, or other infected organs, etc. It is reported in 1-5% of transplant patients. ...Read more

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Can endocarditis lead to sepsis?

Can endocarditis lead to sepsis?

Yes: Depending on the cause of endocarditis. Usually fungal endocarditis won't lead to sepsis/septic shock. ...Read more

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If sibo is not treated, can it lead to sepsis?

If sibo is not treated, can it lead to sepsis?

Highly unlikely: I've never heard of this happening. We all have trillions of bacteria living in our small and large intestines. SIBO is a condition of more bacteria than normal in the small intestines. Sepsis occurs when bacteria are in the bloodstream. It's rare for intestinal bacteria to enter the blood unless there's a perforation of the GI tract. Untreated SIBO shouldn't increase sepsis risk. See comment: ...Read more

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How long does it take for diverticulitis lead to sepsis if left untreated?

How long does it take for diverticulitis lead to sepsis if left untreated?

It varies: If untreated it could take days or it could take weeks. But a diagnosis of diverticulitis should be treated promptly with antibiotics regardless of the risk for progression to sepsis. ...Read more

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I had sepsis 2 years ago following surgery. I don't think organs were damaged. Does sepsis stay in your body forever? Should I be on gaurd?

See below: If no organs were damaged due to the sepsis, it should not leave a lasting problem. You should be on the watch for the circumstances that led to sepsis. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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My 25 yr. Young niece has a sepsis bactrial infection that got into her blood and shutting down vital organs! 25 yr young sick niece went into icu on feb. 26, 2012 and still in icu! too many things have happened since then vital organs shutting down, f

My 25 yr. Young niece has a sepsis bactrial infection that got into her blood and shutting down vital organs! 25 yr young sick niece went into icu on feb. 26, 2012 and still in icu! too many things have happened since then vital organs shutting down, f

Hello. : Hello. Her doctors can make a best estimate on this. They would need to take a large variety of things into account. It would not be possible for a physician who is not intimately knowledgable about her case to provide a life expectancy estimation. I am worry to hear about this. Take care. ...Read more

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I have vomiting episodes that lead to systemic inflammatory response syndrome without sepsis. What causes sirs? Insufficient cortisol from adrenals?

Multifactorial: As a general rule, inflammatory conditions which produce the criteria necessary to term a condition sirs are induced by cytokine release, but there are many other possibilities. Generally not adrenal insufficiency. You seem to be trying to acquire a shorthand medical education. It is not that simple. ...Read more

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Can 4+ weeks of IV Ancef (cefazolin) for sepsis treatment lead to anemia?

No but sepsis does: No, but sepsis itself always causes anemia. When the infection clears up, including any underlying infection that led to sepsis, the anemia will improve. Cefazolin (Ancef®) has nothing to do with it. Discuss with your doctor if you remain concerned. ...Read more

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Can a pre sacrel abscess lead to permanent nerve damage to a bladder. Pain on urination and retention. Have had mass pelvic sepsis which lead to prob?

Can a pre sacrel abscess lead to permanent nerve damage to a bladder.  Pain on urination and retention. Have had mass pelvic sepsis which lead to prob?

Absolutely: Such a difficult problem needs to be checked and followed by a highly educated doc specialist. Sepsis can kill you by the way. No need to wait! doc is necessary. ...Read more