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Doctor insights on: How Does Pernicious Anemia Cause People To Have Achlorhydria

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How does pernicious anemia cause people to have achlorhydria?

How  does pernicious anemia cause people to have achlorhydria?

The other way around: Achlorhydria (lack of adequate gastric acid production and secretion) is one of the causes of pernicious anemia and not the other way around. Normal gastric acid is essential for adequate absorption of vitamin b-12. Vitamin b-12 deficiency in turn causes pernicious anemia. ...Read more

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Pernicious Anemia (Definition)

It is a decline in the amount of red cells in the circulation as a result of impaired production in the bone marrow resulting from a lack of vitamin b12. This is most commonly as a consequence of impaired absorption due to an autoimmune condition affecting the stomach lining. If untreated, it may also lead to brain and spinal cord problems. It is easily ...Read more


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Does pernicious anemia cause high serum b12?

Does pernicious anemia cause high serum b12?

Low vitamin B12.: pernicious anemia is a LOW vitamin B12 state. This occurs when the body fails to make enough of a specific protein to enable the body to absorb vitamin B12. This usually occurs when the immune system attacks a specific cell in the stomach that produces the needed protein. Since the body can't absorb vitamin B12 through the stomach it can be given in a shot and even under the tongue. ...Read more

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Does methadone cause pernicious anemia?

Not likely: Methadone is a very strong opioid medication, with a long list of serious side effects. But pernicious anemia is NOT one of them. Contact your doctor for specific information about your case, re your anemia and specific doses of methadone you are taking. Anemia may be related to other meds you are taking, or an underlying illness. Check with your MD. ...Read more

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Is pernicious anemia genetically caused?

Is pernicious anemia genetically caused?

Not usually: Pernicious anemia is caused by vitamin B12 or Folic Acid deficiency. It may be associated with gastrointestinal or liver problems and should be investigated by your physician. ...Read more

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Is methadone a cause of pernicious anemia?

No: Unaware of any association. True pernicious anemia is an autoimmune disease, caused by antibodies to the cells in our stomachs that produce intrinsic factor, which is needed to absorb vitamin B12 from our intestines. It may be hereditary or acquired. There are other causes of B12 deficiency, including stomach and intestinal diseases/surgery, and lack of B12 in diet. A hematologist can help. ...Read more

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Can 7yrs of undiagnosed coeliacs cause pernicious anemia, irreversible villi damage and miscarriages?

Gi issues: This is a question best answered by a gastro intestinal specialist , i would seek a consult to find this answer. ...Read more

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Can alcoholism cause you to have pernicious anemia?

Can alcoholism cause you to have pernicious anemia?

Yes: Alcoholics usually do not take in adequate amounts of Folic Acid which can lead to megaloblastic anemia. B12 deficiency is less common but possible as well. ...Read more

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What are the causes of pernicious anemia?

What are the causes of pernicious anemia?

Autoimmune disease: Pernicious anemia is an autoimmune disease producing autoantibodies against intrinsic factor found in the lining of the stomach. This leads to lack of absorption of vitamin B12 which is important in making blood cells and for nourishment of the nervous system. Treatment would be by replacement of B12 via injections or absorption into the body by other means (nasal spray). ...Read more

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What are the causes of symptoms in pernicious anemia?

What are the causes of symptoms in pernicious anemia?

Lack of vitamin B12: Pernicious anemia is due to a lack of vitamin b12. B12 is necessary for the normal function of the nervous system and the formation of red blood cells. ...Read more

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Dr. Barbara Lavi
6 doctors shared insights

Achlorhydria (Definition)

Achlorhydria or hypochlorhydria refers to states where the production of gastric acid in the stomach is absent or low, respectively. It is associated with various other medical problems. Usually chronic vomiting causes this. Also seen in hypothyroidism, h pylori infection, ...Read more


Dr. Steven Ginsberg
1,239 doctors shared insights

Anemia (Definition)

Anemia refers to any condition where there is a decrease in the red blood cells in the body. There are numerous causes of anemia but they can basically be broken down into 3 categories: decreased production of red blood cells increased destruction of red ...Read more