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Doctor insights on: How Does Kidney Disease Actually Affect The Immune System

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How does kidney disease actually affect the immune system?

How does kidney disease actually affect the immune system?

Lowers immunity: Kidney diseases usually lowers someone's immunity as evidenced by the high risk of these patients to develop infections (pneumonia, urine infection etc) and their lack to respond appropriately to vaccinations (hepatitis. ...). ...Read more

Kidney (Definition)

The kidneys are paired organs that lie on either side of the vertebral column. Part of their critical functions include the excretion of urine and removal of nitrogenous wastes products from the blood. They regulate acid-base, electrolyte, fluid balance and blood pressure. Through hormonal signals, the kidneys control the ...Read more


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How can kidney disease affect the immune system?

How can kidney disease affect the immune system?

Plenty of reasons: If your kidneys are losing protein in your urine (proteinuria), this can affect the production of antibodies to fight infections.
If your kidney disease is a result of uncontrolled diabetes, elevated blood sugars can lower the immune response to infections.
Finally, if one is on dialysis, great care must be taken to keep the dialysis site sterile as this is often a source of infections. ...Read more

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What's the difference between a kidney disease, and auto immune kidney disease? My protien is 9, 876.

What's the difference between a kidney disease, and auto immune kidney disease? My protien is 9, 876.

Kidney disease: The term kidney disease is a very general term and has no indication of cause. The term autoimmune indicates specifically that an immune attack arose within your body that is attacking the kidney. Therapy typically includes prednisone, plus cytoxan or prograf or cyclosporin or cellcept (mycophenolate mofetil) or imuran. Proteinuria of 9876 is very high and indicates severe attack and leakage of protein. ...Read more

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What effects can losing a kidney have on the body-can it cause fatigue, or affect the immune system?

What effects can losing a kidney have on the body-can it cause fatigue, or affect the immune system?

Single kidney: Loss of one kidney should have no effect on bodily functions. You can live a normal life with one kidney. The one exception would be of you had faling kidneys. In that situation every bit of healthy kidney tissue is needed to maintain kidney functions, so loss of an entire kidney could have a significant consequence. Fatigue and even immune dysfunction could occur with more severe kidney failure. ...Read more

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How does polycystic kidneys affect the immune system?

How does polycystic kidneys affect the immune system?

Not sure: Adult polycystic kidney disease (numerous cysts form in both kidneys. It is a autosomal dominant genetic disease, meaning you inherit it from your parents. Can cause cysts in the liver and pancreas, aneurysms in the brain which can cause stroke.Urinary tract infections, blood in urine, high blood pressure
kidney stones, renal failure, bowel diverticula can occur. No definite immune issues are related. ...Read more

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Can kidney cyst compromise my immune system?

Can kidney cyst compromise my immune system?

No.: One person in four has a simple kidney cyst. Ignore it. I wish all the questions here were this easy! Thanks for writing. ...Read more

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Can the body's immune system fight off a kidney infection? Just curious.

Can the body's immune system fight off a kidney infection? Just curious.

Need clarification: If you're talking about pyelonephritis, an actual kidney infection, then antibiotic use is absolutely essential to management. If you're talking about a urinary tract infection like what most people get, then it depends. Asymptomatic women don't need to be treated but asymptomatic men should. Both symptomatic men and women should get treated. ...Read more

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Does low kidney function cause low immune system with low WBC and platelets? Or would it be the other way around?

Does low kidney function cause low immune system with low WBC and platelets? Or would it be the other way around?

Kidney: Depends on how poorly the kidney function is. It can lead to anemia and sometimes low platelet count. Sounds like you have more going on and should continue seeing your doctor. ...Read more

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Mystery diagnosis... Recurrent liver/kidney function test abnormalities, weak immune system, fatigue, joint pain; but neg rf test... What's up w/me?!

Mystery diagnosis... Recurrent liver/kidney function test abnormalities, weak immune system, fatigue, joint pain; but neg rf test... What's up w/me?!

Could be. ..: The negative rheumatoid factor does not completely exclude rheumatoid arthritis but given the tests and symptoms you mention, it could be lupus erythematosus. You need to see a rheumatologist. Joint pain at your age is not "normal" and the liver and kidney abnormalities could be related. ...Read more

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Woud you please discuss the connections of kidney disease (nephropathy) with other systems?

Pretty broad: Really not enough space to answer. The kidney ultimately effects the metabolism of the entire body, and renal disease can effect the bone marrow, skin, heart, lungs, blood vessels, liver, joints, bones, muscles, etc. ...Read more

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How does chronic kidney disease affect the renal system and organs?

How does chronic kidney disease affect the renal system and organs?

Renal equals kidney: The kidney is the basic engine of the renal system. It is what processes the wastes and corrects the chemicals in the body. The remainder of the renal or genitourinary system is the plumbing that allows the liquid wastes of the body to be eliminated. ...Read more

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What's the best weight loss system for people with polycystic kidney disease?

What's the best weight loss system for people with polycystic kidney disease?

Wt loss: The best weight loss program is always diet and exercise. Avoiding contact sports is important (as cysts can rupture). But most physical exercise is ok. Watching fatty foods, calories and cholesterol is very important. ...Read more

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I apparently have a kidney disease but don't know why. High bp?

I apparently have a kidney disease but don't know why. High bp?

Could be: High BP can cause kidney disease, even if you are already on BP meds. Kidney disease can also cause high bp, which can then cause a viscious cycle of sorts. If you have kidney disease and high bp, it is important to have regular f/u with your kidney doc to treat both conditions optimally. ...Read more

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If chronic kidney disease is so serious, why don’t I feel sick?

If chronic kidney disease is so serious, why don’t I feel sick?

Slow Onset: Chronic kidney disease comes on slowly over a long time. Your body is able to adjust and "get used to" the change. In acute disease, the onset is very fast, no time to adjust and you would feel very ill. Either kind can lead to kidney failure, and eventual dialysis or transplant. ...Read more

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What exactly is the worst that could happen if a kidney disease/infection isn't treated?

What exactly is the worst that could happen if a kidney disease/infection isn't treated?

Not good: If the person became septic they could become terribly ill (maybe even die if severe complications occured). ...Read more

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For centuries children and adults did ok treating polycystic kidney disease with home remedies. Why can't i?

For centuries children and adults did ok treating polycystic kidney disease with home remedies. Why can't i?

We know more now: Polycystic kidney disease has been around for a while, home therapies had the advantage of not being scientifically tested. Thisdisease also causes different degrees of illness in different victims, fooling docs into thinking that the "home remedy" was effective, when the disease was just not as bad in that patient. Home remedies should be used with the help of a doctor. ...Read more

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I do have the results from the hospital and it also says kenny failure kidney disease but I'm puzzled why they didn't do anything?

I do have the results from the hospital and it also says kenny failure kidney disease but I'm puzzled why they didn't do anything?

Need follow up: Woild suggest call and make an appt with a kidney doctor (nephrologist) soon and have your blood work tested and followed by. A urine test is also essential. ...Read more

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I was told I have an Anderson carr kidney is that a kidney disease? Is this life threatening. Online doesn't give much information.

I was told I have an Anderson carr kidney is that a kidney disease? Is this life threatening. Online doesn't give much information.

Anderson Carr Kidney: The modern name is nephrocalcinosis. Too much calcium laid down in your kidney. I specialize in this and need more information from you. Lets do 2nd opinion an we can get into the details.

Has your calcium in blood been high? ...Read more

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What shouldn't I eat/drink if I have polycystic kidney disease?

What shouldn't I eat/drink if I have polycystic kidney disease?

Consistency: Make healthy decisions: low sodium diet, exercise, no tobacco, and be consistent. Take prescribed medications, control blood pressure, avoid all nsaids, if diabetic manage it well, and like everyone it helps to have a little bit of good luck too. Get a nephrologist (kidney doctor) who will look for ways to slow/prevent loss of kidney function, and if needed prepare for end stage kidney disease. ...Read more

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Why would sometimes my GFR be normal and sometimes it be 54 I don't think I have any real signs of kidney disease?

Varying GFR: Your question would be better answered by asking the physician who told you your GFR was 54 ml/min. If it were an estimated gfr, it would have been derived from blood work and you can ask that physician (p) for an opinion as the p is most familiar with you. If you do not have a p, see a nephrologist for an evaluation of your renal function. Good luck. ...Read more

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I have polycystic kidney disease PKD diagnosed when I was 14 now I'm 34 I don't take any meds just living a healthy lifestyle. Is there any meds?

I have polycystic kidney disease PKD diagnosed when I was 14 now I'm 34 I don't take any meds just living a healthy lifestyle. Is there any meds?

Pkd: Adjust diet significantly. Avoid saturated fats. Minimize animal protein to 30 grams per day. Minimize salt. Avoid caffeine. Drink 4 liters of fluid per day. Achieve ideal body weight. Do not smoke. Control blood pressure to 130/80. Avoid trauma. Avoid infection. Soy and omega 3 help daily. Taking ACE inhibitors can help and low dose statin can help. Taking tolvaptan can help but with side effect ...Read more

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I had a bmp which showed my bun was 13 and my creatine was 0.85. Does this mean I don't have any kidney issues or could I still have kidney disease?

I had a bmp which showed my bun was 13 and my creatine was 0.85. Does this mean I don't have any kidney issues or could I still have kidney disease?

No kidney failure,: Although you still could have any kind of kidney disease that doesn't cause decrease in kidney function, like stones, nephrotic syndrome or early stage of kidney disease. ...Read more

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Who have risk of getting chronic kidney diseases in adults?

Who have risk of getting chronic kidney diseases in adults?

Everybody: Today there's a laboratory fad that overdiagnoses 'chronic kidney disease' in all well-muscled individuals based on serum creatinine levels. However, anyone who neglects high blood pressure or kidney infections or does not manage diabetes closely will end up sick bad kidneys, and a few disesaes strike at random. ...Read more

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Does exercise help with kidney disease?

Does exercise help with kidney disease?

Yes: Exercise has a profound impact on health and well-being. Regardless of your health and fitness status, it is possible for you to improve your overall well being and health with regular exercise. As the blood is circulated by exercise, toxins and other waste products are eliminated more efficiently and metabolic functions improve. This allows essential nutrients to be transported more efficiently. ...Read more

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Does a kidney disease affect mental development?

Does a kidney disease affect mental development?

It possibly can: Reflux disease in children can affect mental growth. Recurrent infections, uremia and incontinence may affect mental status or may be associated with neurological conditions. ...Read more

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What illnesses could cause serious kidney disease in a child?

Mostly infections: Bacterial infections that produce certain toxins such as a type of e coli recently found in germany but also present here can cause a serious disorder called hemolytic uremic syndrome with sudden kidney failure.
Streptocaccol infections of a certain type can cause nephritis due to antibodies produced against them. ...Read more

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Can I continue to be an effective nurse with a kidney disease?

Can I continue to be an effective nurse with a kidney disease?

Yes, unless severe: Stages 4 and 5 of chronic kidney disease will be associated with fatigue and feeling poorly that will interfere with work. However, better stages will still be compatible with being able to work ok. Need to note that difference between stage 3 and 4 may be only the difference between 29 & 31 "%" of kidney function and other associated illnesses will also modify the above conclusion. ...Read more

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Is kidney disease something I should seek a second opinion about?

Kidney Disease: It depends what kind of kidney disease you have. Kidney is a vital organ and there several different kidney diseases.So give us more detail or if you want second opinio, consult a nephrologist or urologist depending on what your condition is. ...Read more

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What will happen to my kidney disease if I get in really good shape?

Depends on disease: Hard to answer. It depends on the type and severity of the kidney disease. Controlling blood pressure, salt intake, and urinary tract infections is the best way to maintain kidney function. ...Read more

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What symptoms are you having when you find out you have kidney disease?

What symptoms are you having when you find out you have kidney disease?

Varies widely.: The symptoms & signs of kidney failure vary widely. It depends on the degree of kidney underfunction, the onset, the cause, & the duration. If gradual, there may be no initial symptoms. Sometimes there is blood in the urine & flank pain. Ultimately, hypertension, swelling & uremia results: anorexia, nausea, vomiting, pericarditis, peripheral neuropathy, and central nervous system abnormalities. ...Read more

Previous Kidney Disease (Definition)

Polycystic kidney disease is a kidney disorder passed down through families in which multiple cysts form on the kidneys, causing ...Read more


Dr. Tarek Naguib
2,396 Doctors shared insights