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Doctor insights on: How Does Epinephrine Affect The Heart

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How does epinephrine affect the heart?

How does epinephrine affect the heart?

Epinephrine: Epi causes both blood vessel constriction and increased force of contraction. It usually also increases the rate of contraction. It usually increases blood pressure and cardiac output. These are acute effects.

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Dr. Chad Levitt
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How long can epinephrine affect your heart?

How long can epinephrine affect your heart?

A few minutes: The half-life of Epinephrine is about 2 minutes. We constantly release small amounts. This is increased by the "fight or flight" reflex, and when administered medically. The most common use is in local anesthesia, and the effects wear off quickly.

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Why does epinephrine increase heart rate?

Why does epinephrine increase heart rate?

Binding receptors: Do you mean how does it increase heart rate? The mechanism of action is quite complicated but in simple term, it binds to the beta adrenergic receptors on the heart leading to changes in calcium level and increases in the firing rate of the pacemaker cells.

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Can you tell me how halothane sensitizes the heart to epinephrine?

Can you tell me how halothane sensitizes the heart to epinephrine?

It blocks: potassium channels. I doubt you will find Halothane anymore in any US operating room

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Epinephrine -- does it's use cause a heart attack or stroke?

Epinephrine -- does it's use cause a heart attack or stroke?

Maybe: There is too much of a good thing. Epinephrine is a natural hormone with necessary functions. Too much can, and does, cause heart attack, hypertension, anxiety, stroke. Aside from exogenous sources, few natural conditions cause excess Epinephrine (eg, pheochromocytoma).

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What makes heart rate increase during exercise besides epinephrine?

What makes heart rate increase during exercise besides epinephrine?

Many factors: Humidity, altitude, oxygen tension, thermal are just a few examples. Dehydration as well as increasing the core body temp are very influential on raising your heart rate. How good your fitness level is also important.

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Should I inject someone with an epipen (epinephrine) if that person has no heart beat?

Should I inject someone with an epipen (epinephrine) if that person has no heart beat?

Depends: If a person is having anaphylactic shock, their blood vessels may suddenly dilate. This can cause their blood pressure to drop, sometimes quite considerably. If the blood pressure is too low, the pulse may not be able to be felt; the heart is, however, still beating in this case. If a person is having anaphylactic shock, they need emergent treatment.

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Adverse effect of Epinephrine is arthymia of the heart, why? Our body makes this naturally and designed to use it so why would it cause this effect?

Epinephrine: Any time you have a problem as you report you must see your primary doctor to get things under better control.

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Can't use epinephrine I get rapid heart rate, endodontist wants to give me 20 mg Valium crushed 1/2 hour before root canal. Is this ok?

Can't use epinephrine I get rapid heart rate, endodontist wants to give me 20 mg Valium crushed 1/2 hour before root canal. Is this ok?

Epinephrine: After over 40 years of dental practice I have had only a handful of patients who truly are sensitive to Epinephrine in local anesthetics. Almost all patient who say they react with an increased heart rate do so because of the release of their own epi due to anxiety, or react from poor injection technique. Ask your dentist about the use of sweet air instead of valium. Btw ok with precautions.

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Can novacaine cause a heart attack? What are the side effects of epinephrine?

Novacaine heart att: Novacaine can cause heart problems if it is overdosed. Will decrease the absorption of the novacaine into your blood, but it to can cause heart problems when injected directly into the blood stream. A heart attack happens when the oxygen consumption in the heart exceeds the blood supply to a section of heart. This is more likely to happen whith an unintended bloodstream injection of epinephrine.

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What does gait weakness mean? Also, any idea what would cause elevated epinephrine levels and heart rates that race multiple times a night and races at the slightest movement?

What does gait weakness mean? Also, any idea what would cause elevated epinephrine levels and heart rates that race multiple times a night and races at the slightest movement?

Pheochromocytoma: A pheochromocytoma is a growth in the area of the adrenal glands that causes hypertension, elevated catecholamine levels and palpitations. It is not a common condition and an endocrinologist is best qualified to evaluate for one and I recommend that you consult one in view of your symptoms. He/she will order the appropriate tests and refer you to a cardiologist if it is deemed advisable.

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How high does epinephrine have to be to be considered a pheochromocytoma? Also, I have attacks multiple times a night (every night) with heart rates as high as 174bpm. Used to have episodes of nausea,

How high does epinephrine have to be to be considered a pheochromocytoma? Also, I have attacks multiple times a night (every night) with heart rates as high as 174bpm. Used to have episodes of nausea,

This question is: Really complex, and I am concerned that an answer may only make things more confusing if it is too specific. I think in situations like this a thorough history and physical by an internal medicine doctor and possibly a second opinion would be a great way to shed light on something that seems foggy. Pheochromocytoma is truly rare. There are common things that should be looked into first. Best 2 U.

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The dentist may use anesthetic such as 0.3ml lidocaine with 1:100, 000 epinephrine. Would this interact/ have problems with my heart or BP medication.

The dentist may use anesthetic such as 0.3ml lidocaine with 1:100, 000 epinephrine. Would this interact/ have problems with my heart or BP medication.

Little concern: Stress form the procedure, particularly if you were not numb, would cause your body to release more Epinephrine then what is in the local anesthetic. That said I do try to error on the side of caution depending on the heart condition by not using the maximum dose (approximately 8 full injections) and breaking up multiple procedures over several appointments.

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What does ER do if a patient with heart disease and tachycardia has anaphylaxis shock? Do they still give epinephrine injection?

What does ER do if a patient with heart disease and tachycardia has anaphylaxis shock? Do they still give epinephrine injection?

Usualloy yes.: Tachycardia is frequently caused by anaphylaxis. The only drug that truly treats the condition is epinephrine. Therefore, the drug should still be used in patients with heart disease. However, a good way of reducing the danger from the medication is to give lower initial doses, e.g. A pediatric dose of 0.15mg im, which can be repeated every 10 minutes as necessary.

Dr. Mohammad Shahzad
999 Doctors shared insights

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