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How Does Coronary Artery Disease Disrupt Homeostasis
Arteries are defined as blood vessels which carry blood away from the heart (to either the body or lungs). Arteries: higher pressure, thicker walls, stretch (pulse) with each heart contraction & deliver blood to the arterioles which control the flow to individual capillaries. Veins are blood vessels which carry blood from capillaries back to the heart (body to right heart; ...Read more
By blocking the flow: In young, healthy individuals the inner lining of the blood vessels is clean and smooth. Overtime, for many reasons, the inner surface of the heart blood vessels (coronary arteries) may start becoming bumpy/lumpy or blocked due to fat (cholesterol) deposits called "atherosclerotic plaque". This in turn reduces the amount of blood flow available causing "ischemia" (oxygen deprivation).
Slowly: Low density lipoprotein (ldl) is taken up by endothelial cells in blood vessels. The LDL is broken down (oxidized) and absorbed by macrophages within the wall of the blood vessel. Ultimately, the macrophage which is full of oxidized LDL will die. The dead cells and cholesterol accumulate in the wall of the artery interfering with the flow of blood.See 1 more doctor answer
Symptoms/lifespan: Coronary artery disease affects the quality of life and the length of life. Quality of life is affected by reduced functional capacity (ability to do things), chest pain, shortness of breath, loss of employment, and hospitalization. Length of life is reduced as a result of sudden death and myocardial infarction.See 1 more doctor answer
Does coronary artery disease directly cause ventricular tachycardia or is it after heart attacks and damage etc?
Certainly: Evaluation by a primary care & cardiologist, reduce weight - BMI < 28, eat right: low fat, low (bad) cholesterol, consider high quality fish oil, cessation of smoking, exercise (if you are healthy enough per your physician), reduce alcohol consumption, take prescribed medications as directed. Know your numbers: cholesterol, blood pressure, blood sugar and work with your physician to optimize them.See 1 more doctor answer
Minimize the Drivers: Optimize lipoprotein concentrations (ldl ; hdl, not cholesterol), low normal blood glucose: hba1c <5.0, low normal bp, don't smoke, stay physically active, confront and resolve stress, etc. This is the best approach. Conventional medical methods, angioplasty, stents, bypass surgery, etc. Only partially treat the symptoms ; further complicate the disease process (i have experience will all these).See 1 more doctor answer
AtherosclerosisClots: The key issue is atherosclerosis: accumulation of white blood cells in the walls of arteries, typically starts in childhood & is primarily driven by lipoproteins (proteins which transport fat in the water outside cells) is dominant human behavior yet is typically ignored for decades because it remains asymptomatic until plaque ruptures release debris, triggers clots & suddenly blocks blood flow.See 1 more doctor answer
Cath lab, CT, scans: CT scan can do a calcium count, which is related to disease. Cath lab can create dye studies of the arteries, which show blockage. A myocardial perfusion scan can show abnormal areas of blood flow on the heart, which is related to blocked arteries. 256 bit CT scans are getting very good at showing artery disease also.
Several test.: There are several tests for coronary artery disease. A thorough history and physical exam, ekg, ct scan, nuclear studies are all helpful but the best test is a cardiac catheterization. The cardiologist will place a small catheter through a groin vessel up to the heart and inject a special dye into the coronary arteries. The pictures will show if there are any blockages or not.See 1 more doctor answer
Various: If you're asking how CAD is diagnosed, there are actually many ways. Direct testing can show it (ie stress test, calcium scan, catheterization). We also consider the presence of vascular disease elsewhere in the body to be equiv. To having cad. So if someone has blocked circulation in the legs, or a history of certain kinds of stroke, they'd be treated like they have cad. It's a systemic process.See 1 more doctor answer
The leading cause of death and disability in adults in the U.S. It develops when lipid (fatty) plaques builds up in the arteries, thereby stopping blood flow to the organ supplied by that artery. If the artery supplies the heart, blockage causes a heart attack. If the blockage is in a brain vessel, the ...Read more
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