Doctor insights on:
How Does Cancer Spread Among Lymph Nodes
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Very unlikely: Colon cancer that does not involve lymph nodes should not have neck lymph node involvement. If you recently had surgery you probably had a central catheter placed in your neck for IV administration. This may be the lump you are feeling. Make sure you talk to your doctor at the next visit to have a look. You could also have swelling from the endotrachral tube. ...Read moreSee 1 more doctor answer
Makes them bigger...: Lymph nodes are basically a place where normal white blood cells reside. Leukemic cells, which are cancerous white blood cells, will sometimes go to lymph nodes and divide rapidly, which in turn makes the lymph node grow abnormally large. ...Read more
That depends on: what you mean. Hodgkins lymphoma or non- Hodgkins lymphoma start in lymph system. If there is cancer found in a lymph node (& not a lymphatic cancer) then it is metastatic from where it originated. But having a painful or swollen lymph doesn't automatically mean that there is cancer in that particular node. It needs to be tested to know. ...Read moreSee 1 more doctor answer
It is relative.: This depends upon the stage of cancer at diagnosis. Colon cancer is staged by the dukes' system. Stages a and b have no lymph mode involvement and so no spread is likely. Stage c patients do better if <5 nodes are involved so those are likely to be slower than those with >5 nodes. Stage d means distant metastasis (organs involved). It is hard to say since people come in at diferent stages. ...Read moreSee 1 more doctor answer
It depends: It depends on the type of leukemia. All leukemias affect your immune system, because leukemia is abnormal growth of white blood cells. In acute leukemia, the tumor cells grow in the blood and usually the lymph nodes aren't enlarged. In chronic leukemia, (cll or cml) the lymph nodes can become enlarged from leukemia cells growing within. ...Read moreSee 1 more doctor answer
Local and distant: The most common spread is to local nodes around the esophagus. But the spread, or metastasis can be more distant such as to nodes around the celiac plexus, the region where the blood supply to the stomach arises below the diaphragm. But distant metastasis can be to nodes in the neck, particularly associated with the lymphatic chain that drains into the subclavian vein on left behind clavicle ...Read moreSee 1 more doctor answer
Must be evaluated: There is no way for you personally to know the cause of swollen lymph nodes in your neck. You should visit your doctor the great majority of the time, they are coming from an infection in your throat, mouth, face, or even infection in the nodes themselves. Cancer can be a cause but is less liely. Go and find out for sure. ...Read more
Spread from marrow: Swollen lymph nodes do not transform to leukemia. Leukemia is a cancer starting in the blood cells of the bone marrow.,Their rapid growth allows them to build up in the bone marrow, replacing normal cells. At some point they leave the bone marrow and enter the blood stream. . Once in the blood, leukemia cells can spread to other organs including the lymph nodes, liver, and spleen. ...Read more
Can oral or oropharyngeal cancer spread to supraclavicular nodes without spreading to other cervical nodes first?
Unusual but possible: As we are taught in fellowship, "tumors don't read text books." supraclavicular nodal metastasis is a distant site, technically stage iv. Usually the pattern is regional spread followed by more distant spread, but sometimes there are "skip" situations. Best of luck. ...Read moreSee 1 more doctor answer
Absolutely!: Lymph node (ln) involvement implies the presence of cancer cells "elsewhere" in the body. Therefore, the chance for cure is dependent on one's ability to kill these cancer cells thru a combination of chemotherapy & one's immune system. Fortunately, we have many effective drugs to rx breast ca, leading to improved cure rates as compared to even a decade ago. Ln involvement is not a death sentence. ...Read more
Could cancer metastase to distant regional lymph nodes before it metastase to the nearby lymph nodes?
No: tumors metastasize to regional nodes before distant nodes, but what goes to nodal disease only stays nodal. When breast spreads to nodes, one pos. axillary node is said to have better prognosis that 10 nodes. This is not due to # nodes but more nodes means primary has been spreading over a longer period of time. If axilla speads it is only to supraclavicular nodes and no other site. ...Read more
Not necessarily: Lymph nodes are one aspect of evaluation for stage and treatment of breast cancer. It depends on size of breast cancer itself, number of lymph nodes involved, hormone status of the tumor, and dna testing can also help identify breast cancer risks. If the lymph node involvement is small, then there is little additioanl risk to the patient. There are many factors involved in assessing breast cancer. ...Read moreSee 1 more doctor answer
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