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Doctor insights on: How Does Cancer Cells Develop

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How does cancer develop? In cells or what?

How does cancer develop? In cells or what?

Multiple steps: Cancer is multi-step process of accumulating defects in the genome of the cells exposed to various insults, including inherited damage. The changes often start by facilitating the growth of cells and additional damage to the cells accrues that enables them to grow unchecked, acquire the ability to invade and metastasize. A human cancer has about 90 genetic defects. ...Read more

Dr. Barry Rosen
4,369 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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How does breast cancer develop exactly?

How does breast cancer develop exactly?

Breast cancer: Cont'd: cancer cells are unique in that they also develop the ability to break off form the mother cell, land somewhere, and grow into new tumors by just continually dividing like the mother cell. This is called metastasis. ...Read more

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How does tongue cancer develop?

How does tongue cancer develop?

Tobacco, alcohol: The majority of people who get tongue cancer have a strong history of tobacco use (either smoking or chewing) and/or alcohol use. The combination of the two increases the risk even more. The best thing you can do to reduce your risk is to eliminate tobacco use and moderate your alcohol consumption. ...Read more

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How long does ovarian cancer take to develop into stage 3/4?

How long does ovarian cancer take to develop into stage 3/4?

Hard to know: Most ovarian cancers are already stage 3 or 4 when they are diagnosed so we really don't know how long it took them to get there. In retrospect, many women have had symptoms for many months before their diagnosis. There may also be an asymptomatic stage that could last for months or even years before the symptoms begin. ...Read more

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How does breast cancer develop?

How does breast cancer develop?

One mutant cell: One normal cell inside your breast mutates (becomes abnormal), and begins to grow. The normal "stop" signal that tell a cell to stop dividing doesn't work, so the cells keep dividing. One cell becomes two, two become four, four become eight, etc. It takes millions of cancer cells to form a tumor you can feel. ...Read more

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How does colon cancer generally develop?

How does colon cancer generally develop?

From polyps usually: Almost all colon cancers start off as a polyp, hence the push for colonoscopy screening looking for polyps. Only 20% of colon cancers are hereditary, meaning the rest are environmentally related to foods we eat and chemicals we are exposed too. If you are over 50 or have risl factors get regular colonoscopies. ...Read more

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How does skin cancer kill?

How does skin cancer kill?

Slowly.: Cancer cells are damaged cells that can't stop reproducing. So they keep multiplying and don't stop. These cells also create a blood supply that feeds them all the nutrients you eat. Sometimes they spread to other areas of the body and keep multiplying and feeding off your food. Eventually your body doesn't get most of the nutrients and slowly dies while the cancer grows by stealing food. ...Read more

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How does melphalan kill cancer cells?

How does melphalan kill cancer cells?

Halt division: Melphalan or Alkeran (melphalan) is l phenylalanine mustard an alkylating agent acts on guanine based dna by halting cancer cell division. ...Read more

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How does childhood cancer develop?

How does childhood cancer develop?

Childhood cancer: This is an intense area of current research. There are inherited syndromes that lead to pediatric cancer, but most cases are not. Studying patient tumors have found some mutations in dna, but why these happen we do not know. Is it a random error (bad luck, if you will) or an unknown genetic predisposition? A defect in gene regulation (epigenetic defect)? No evidence yet for exposure. ...Read more

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How does chemoembolization kill cancer cells?

How does chemoembolization kill cancer cells?

2 methods: The first is that the particles/medicine clogs the blood vessels that provide essential oxygen and nutrients to the cancer growth. The second is that the chemotherapy medicine that is injected prevents the cancer cells from dividing and growing. ...Read more

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How exactly does capsaicin cause apoptosis in cancer cells?

How exactly does capsaicin cause apoptosis in cancer cells?

Possibly many ways.: This is the active ingredient in chili peppers that causes a burning sensation. It binds to the vanilloid receptor subtype 1 (vr1), which triggers a temperature oriented inflammatory reaction. Some of its effects on cancer are inconclusive, like stomach cancer. It appears to have proposed effects of other cancers, like breast cancer by causing apoptosis by affecting the egfr/her-2 pathway. ...Read more

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How does pancreatic cancer kill the body?

How does pancreatic cancer kill the body?

Spread : Common sites are liver and peritoneal cavity leading to ascites, jaundice, liver failure. Obstructed bile ducts and invasion into coeliac neural plexus can cause agonizing pain. Cancers of the head and pancreatic neck may differ from ampulla or pancreatic tail. The latter have longer survival and somewhat better prognosis. ...Read more

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How does cancer affect cells in the body?

How does cancer affect cells in the body?

Invade organs: As the cancer grows it produces a proteinase that allows for invasion of blood vessels. It breaks down -e-cadherin to s-ecadherin that allows metastasis. The spread is predetermined by the surface protein on the tumor cell. Once spead to an organ occurs it can grow in that organ and in many instances can destroy the organ function such as liver If TNFproduced cacchexia occurs. ...Read more

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How does liver cancer typically develop? And does alcohol contribute to liver cancer?

How does liver cancer typically develop? And does alcohol contribute to liver cancer?

Various causes: There are various risk factors for liver cancer: genetic predisposition, environmental factors, chronic hepatitis C infection, chronic hepatitis B infection, other types of liver disease. Yes, alcohol use is a risk factor for developing liver cancer too. Avoiding alcohol completely or drinking in moderation is best thing to do. ...Read more

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How long does it takes for HPV precancerous cell to turn in to cancer cells?

How long does it takes for HPV precancerous cell to turn in to cancer cells?

Varies: Most people infected with hpv are able to eliminate the virus. The latent period for the development of cancer is variable and depends on the strain of hpv virus, genetic make of the individual, use of tobacco, hormonal status and immune status. The latent period is usually measured in years. ...Read more

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How can cancer cells take over?

Cancer cells: Have lost most if not all of the control mechanisms normal cells have, so they grow uncontrollably and spread to other organs, ultimately causing irreversible damage to vital systems and death. It is more complex than that, of course, but we have a limited space to answer. ...Read more

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How can some cells become cancer?

How can some cells become cancer?

Genes & environment: Cancer arises from genetic changes in cells that lead to their uncontrolled growth. These changes arise from a complex interplay between our inherited genes and our environmental exposures. Hereditary cancers occur when defective genes are inherited, predisposing cells to become malignant. Environmental damage (smoking, hpv, radiation, diet) to cells also can cause these transformations. ...Read more

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How can some cells become cancer?

How can some cells become cancer?

No short answer: Changes to dna is a final common pathway. Things we do (smoke, drink alcohol, obesity) can contribute. Environmental exposures ( toxic waste, radiation, excessive sun exposure) are also causes. Inherited gene mutations ( brca in breast, hnpcc in colon, men in endocrine tumors) confer higher than average risk for those families. Best to avoid bad things, and do screening tests at the right age. ...Read more

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How does bone cancer kill a person?

How does bone cancer kill a person?

Invasion: Cancer will kill you if the cancer cells invade healthy tissue/organs and impair their function. With "bone cancer", this can occur by affecting blood cell production in the bone, or the cancer can metastasize to other organs and cause organ failiure. ...Read more

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How long does cervical cancer take to develop?

How long does cervical cancer take to develop?

10-15 years: Cervical cancer is felt to almost always be related to certain strains of HPV infection through prior sexual contact. Most cases of HPV infection do not turn in to cancer. It's believed to take many years for these tissue changes to turn into cancer. It's believed to usually take between 10-15 yrs, even up to 30. However, like most things there's likely much variation, and may be sooner in some ...Read more

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How does cancer develop? In cells or what?

Multiple steps: Cancer is multi-step process of accumulating defects in the genome of the cells exposed to various insults, including inherited damage. The changes often start by facilitating the growth of cells and additional damage to the cells accrues that enables them to grow unchecked, acquire the ability to invade and metastasize. A human cancer has about 90 genetic defects. ...Read more

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How can cancer cells take over?

Cancer cells: Have lost most if not all of the control mechanisms normal cells have, so they grow uncontrollably and spread to other organs, ultimately causing irreversible damage to vital systems and death. It is more complex than that, of course, but we have a limited space to answer. ...Read more

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What are the danger of cancer cells?

"Spread": What makes a cancer "evil" is the potential to break away from its organ of origin and take up residence in another one;when evident, we call this metastases. We can correlate the probability of cancer cells being "elsewhere" with its stage.Based on the stage & the unique molecular features of the tumor, we may recommend chemotherapy to kill cells that may have gone to other organs. ...Read more

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What occurs if you ate cancer cells?

What occurs if you ate cancer cells?

Ugh....: Hannibal lecter may have eaten some and he is cancer free. Seriously, gastric acid should dissolve any cell not killed by cooking (please tell me it was not raw!). No chance of getting cancer that way. Weirdly interesting question. ...Read more

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What converts normal to cancer cells?

What converts normal to cancer cells?

Multiple steps: Changes in the dna of cells, some changes may be inherited, increase the growth rate of cells and additional changes to the 'dna develop and select for more growth. Many incipient cancers probably die out in the process. As more dna changes promoting growth accumulate the abnormal cells become autonomous, invade and metastasize. On average a cancer has 90 dna changes/mutations. ...Read more

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What can you tell me about cancer cells?

What can you tell me about cancer cells?

One mutant cell: One normal cell inside your body mutates (becomes abnormal), and begins to divide. The normal "stop" signal that tell a cell to stop dividing doesn't work, so the cells keep dividing. One cell becomes two, two become four, four become eight, etc. It takes millions of cancer cells to form a tumor that can be seen on an X-ray or felt on exam. ...Read more

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How do you find the different cancer cells?

How do you find the different cancer cells?

Under the Microscope: Cancer is usually diagnosed by performing a biopsy of the area of suspicion. The tissue is examined by a pathologist for microscopic evaluation, supplemented by special tests to look for proteins associated with certain cancers. ...Read more

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Can cancer cells continue living after you die?

No: They die with the person -- perhaps even a bit faster as they're generally less adaptable. ...Read more

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How to know when do cancer cells begin growing?

How to know when do cancer cells begin growing?

That is a vague ques: Cancer cells are rarely quiet...They are nearly always growing although there is a theory of dormancy which is talked about but it is hard to prove it! ...Read more

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Please help! what happens in cancer cell biology?

Please help! what happens in cancer cell biology?

Man, there are : ..Entire books meant to answer that. Cells have instructions in their dna that establish their behavior. Sometimes those instructions are changed (mutations) and the cells start dividing too much, "learn" how to spread, and bypass their "self destruct" mechanisms. That ultimately leads to a malignancy. It is way more complicated that that but i ain't got space. Try the acs or the nci websites. ...Read more

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Are all cancer cells the same regardless of organ?

Are all cancer cells the same regardless of organ?

No: Cancer is basically the body's cells that mutate and grow out of control at the expense of healthy cells. Because the body has many types of cells, there are many types of cancer cells. Even cells of the same type can have different mutations. This is why cancer is hard to cure. Pathologists and oncologists study these differences to create treatment plans for each patient's unique case. ...Read more

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What are the ways that cancer cells begin to grow?

Sequential mutations: series of gene changes usually beginning with p53 giving immortality to the cell. Then genes induce oncofetal proteins which function to allow fetus to mature and then turn off. Post translational modifications in the proteins of these genes which have been demethylated by virus or carcinogen lead to cells producing the cancer protein and then phenotypically change to the malignancy. ...Read more

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How do cancer cells spread from their original site?

How do cancer cells spread from their original site?

Multi-step process: Cancer develops due to progressive damage to the genome of the cells exposed to various insults. The initial change facilitates cell growth and additional damage changes the dna of the cells that enables them to grow unchecked, invade local tissues, including lymphatics and blood vessels. The malignant cells are then carried through the lymph and/or blood to other organs. ...Read more

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In what ways are cancer cells different from other cells?

Destabilized: By the time it's part of an invasive cancer, the genome of a clone of cancer cell has taken enough mutations that it's remembered how to do things that adult cells shouldn't do (invade, spread, recruit other cells to help with the mischief.) eventually, the genome loses the ability to prevent more mutations from accumulating rapidly. Natural selection as in nature, but in the body. ...Read more

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Can you tell me, how are drugs used to treat cancer cells?

Can you tell me, how are drugs used to treat cancer cells?

Chemotherapy: Drugs that are used to treat cancer come in different types, but most fall under the category of chemotherapy. These drugs interfere with the cancer cells' ability to reproduce. There are other drugs called targeted therapies or immunotherapies. The treatment type is different for each cancer. ...Read more

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Can you tell me how cancer cells differ from regular cells?

They invade : Cancer cells have mutations in what are called proto oncogenes that allow the cell to divide when there are abnormalities in their DNA that would normally be repaired. These mutations allow the metabolic pathway to be altered to use anaerobic glycolysis, produce invasive enzymes known as metalloproteinases and reach immortality by having the telomerase enzyme activated for immortality ...Read more

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How long does it take a cancer cell to grow to 5 centimeters?

How long does it take a cancer cell to grow to 5 centimeters?

This is surprisingly: Complex question. How long it takes for a mass to achieve a given size is highly variable and depends upon the rate of cell cycle progression, growth fraction (% of cells in the tumor that are dividing), rate of cell death that balances emergence of new cells, etc. Some cancers grow rapidly (eg., burkitt lymphoma) while others may take years to achieve comparable size. Why do you ask? ...Read more

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Is it possible to stop cancer cells mutating if caught early?

Is it possible to stop cancer cells mutating if caught early?

By removing them: The best way to stop the cancer cells from mutating is to put them in a bucket! early detection offers the best chance for a cure. ...Read more

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Is it true that every human has a cancer cells in their body ?

The story that: Our bodies may develop genetic changes that if not checked could lead to overt cancer, but the surveillance role of the immune system, when working optimally, can identify and destroy. But i'd not endorse the idea that "every human" has viable cancer cells in their body. ...Read more

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What is the difference between healthy cells and cancer cells?

Abnormal signaling..: Normal cells can grow and divide, but they do so in a manner that is not detrimental to a person. When they receive cellular signaling that says "stop dividing", they listen. Cancer cells have lost this control. Usually cancer cells acquire mutations that both drive the cells to divide while at the same time cause them to cease responding to signals that say stop dividing. ...Read more