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Doctor insights on: How Does A Peptic Ulcer Disease Affect Your Digestive System

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Dr. Nicholas Karyotakis
555 doctors shared insights

Stomach Ulcer (Definition)

Stomach ulcers, also called peptic ulcers, are erosions in the wall of the stomach that can result in bleeding or pain. They can be caused by ibuprofen and similar medicines called non-steroidal anti-inflammatory drugs (NSAIDs), or by infection with a bacteria called H. pylori that ...Read more


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What are common symptoms of peptic ulcer disease?

Pain, nausea: Most ulcers are probably asymptomatic but common symptoms include mid upper abdominal pain, nausea, vomiting, weight loss, and black tarry stools. ...Read more

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What are recently approved drugs for the management of peptic ulcer disease?

What are recently approved drugs for the management of peptic ulcer disease?

Define recent: Pylera is a combo pill used to treat helicobacter pylori which causes ulcers. Dexilant (dexlansoprazole) is a proton-pump inhibitor in the same class as Prilosec and Nexium which helps to heal ulcers. ...Read more

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Can peptic ulcer disease lead to cancer?

Rarely: Peptic ulcers and stomach cancer are both caused, in part, by helicobacter infection. A stomach cancer may present as an ulcer. A bona fide peptic almost never turns into cancer. ...Read more

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Are there any other treatment options for peptic ulcer disease?

Are there any other treatment options for peptic ulcer disease?

Please see: Please see your gastroenterologist for evaluation and to discuss treatment options. This way you can get the correct answer. ...Read more

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Who is more likely to be affected by peptic ulcer disease?

Who is more likely to be affected by peptic ulcer disease?

Someone taking NSAID: The 2 most common causes of stomach or duodenal ulcers are infection with the helicobacter pylori bacteria and the use of non-steroidal anti-inflammatory (NSAID) drugs such as aspirin, ibuprofen, naproxen, meloxicam, etc. ...Read more

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Does peptic ulcer disease lead to weight loss?

Does peptic ulcer disease lead to weight loss?

Weight loss and PUD: Involuntary weight loss is always considered a clinical "red flag." that being said, it is not a surprise that peptic ulcer disease patients may experience less interest in eating due to the pain that meals engender. Under such circumstance, weight loss may follow. However, stomach ulcers may on occasion arise in the setting of cancer, severe physiologic stress, trauma. Don't ignore "red flags.". ...Read more

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Is peptic ulcer disease also related to having pernicious anemia?

Is peptic ulcer disease also related to having pernicious anemia?

Ulcer/infection: Vitamin B12 requires intrinsic factor secreted by the stomach in order to be absorbed. If enough of the stomach cells have been damaged by ulcers, a lack of intrinsic factor secretion could lead to a decreased absorption of B12 and pernicious anemia. Infection with helicobacter pylori can lead to chronic gastritis which can also lead to both ulcers and anemia. ...Read more

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Can patients with peptic ulcer disease pud have pernicious anemia?

Hopefully not: If you are managed with chronic acid reducing medications, you run the risk of low B12 levels in your blood. Get tested and supplement if recommended. You should not experience B12 anemia if under medical care. ...Read more

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My mom is suffering from peptic ulcer disease....she went to a doctor & the doctor gave her triple therapy...but that doesn't work...what can I do ?

My mom is suffering from peptic ulcer disease....she went to a doctor & the doctor gave her triple therapy...but that doesn't work...what can I do ?

Peptic ulcer: Triple therapy is used for the eradication of h pylori disease she may need to have a repeat course sometimes first course does not work. I f she still continue s to have pain then she needs to be reassessed by her GI doctor ...Read more

Dr. Scott Bolhack
2,050 doctors shared insights

Ulcer (Definition)

An ulcer is a discontinuity or a break in a body membrane that impedes the normal functioning of the organ of which that membrane is a part. Ulcers are further classified by their location. Ulcers are usually caused by infections, excessive acid production, stress, ...Read more


Ulceration (Definition)

An ulcer is a discontinuity or a break in a bodily membrane that impedes the organ of which that membrane is a part from continuing its normal functions. Ulcers are further classified by their location, for example; ...Read more