Doctor insights on:
How Do You Know When To Get Off Cytoxan
Cyclophosphamide: "“Cyclophosphamide is contraindicated in patients who have a history of severe hypersensitivity reactions to it, any of its metabolites, or to other components of the product. Possible cross-sensitivity with other alkylating agents can occur. Cyclophosphamide is contraindicated in patients with urinary outflow obstruction.” See: http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=591d9955-3d9 ...Read more
Cytoxan (cyclophosphamide): Cytoxan (cyclophosphamide) is one type of drug that has been used widely to treat different problems such as - rheumatological problem , blood disorder and different kind of cancer- blood and solid cancer. Yes, it is an effective treatment -if it is used in appropriate setting. For furthe info regarding Cytoxan (cyclophosphamide) - open this link: http://www.Nlm.Nih.Gov/medlineplus/druginfo/meds/a682080.Html. ...Read moreSee 1 more doctor answer
Good, but....: PredForte is considered first line. Serious uveitis is best treated the Himira or Enbrel (etanercept) like TNF-alpha inhibitors. Cyclophosphamide works as do other immunosuppressants! Keep in mind that chronic, recurrent uveitis can lead to glaucoma and is associated with a number of rheumatic diseases: sarcoidosis, spondylitis, Reiter's, psoriatic arthritis, etc! ...Read more
While these agents: (alkylators) were the standfast drugs from the 1960's, their main role now is in very high doses prior to bone marrow or stem cell transplants. They reduce some cancers, particularly lymphoma and perhaps breast cancer, but the class is limited by marrow toxicity, resistance, and late effects. It can reduce some tumors, very few, but is usless in many. ...Read more
Reduction in WBC: Cytoxan (cyclophosphamide) can be used in two ways. When given in combination with other chemotherapeutic agents such as CMF it has strong tumoricdal effects on the treated lesion such as breast carcinoma. It essentially acts in a similar fashion on DNA the way nitrogen mustard effected tumors in the past. When used in low doses, it is effective in minimizing suppressor T cell activity. ...Read more
Nausea, vomiting: Cytoxan (cyclophosphamide) can be given orally or intravenously at various different dosage ranges. Nausea and vomiting are probaly the most common side-effects. Abdominal pain can occur sometimes when given orally. Hair loss, drop in blood counts, fatigue, loss of appetite, discoloration of the skin are not uncommon. High doses can irritate the urinary bladder and can cause blood in the urine. ...Read more
I'm on chemio and my skin is so dry what is the reasons for this? I'm taking cytoxan, (cyclophosphamide) thank you
It depends: It's extremely helpful for some cases of lupus kidney disease, has little to offer for other presentations. The whole business of treating lupus is complicated enough that there's room for you to make an informed decision between possible Rx's. In my college days, lupus was often a death sentence; now it tends to be manageable but still difficult. Good luck. ...Read more
Short periods: Both of these drugs are metabolized over a short period of time. They are greater than 99% metabolized (removed) from the body within 5-7 days of administration. ...Read more
Indefinitely: With appropriate monitoring by a physician experienced in using this medication - as long as you need it. Is it working? That's the big question. ...Read more
It depends on why.: Scleritis is inflammation of the white of your eye. It can be associated with other autoimmune conditions. It is usually treated with mild anti-inflammatory medications. For severe scleritis, Cytoxan (cyclophosphamide) might be used. This is a strong immune-suppressing drug that is also a type of chemotherapy. I notice you take methotrexate, which is similar to Cytoxan (cyclophosphamide). Ask your doctor about taking both. ...Read more
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