Doctor insights on:
How Do You Get Lupus Anticoagulant
Part of lupus : You produce antibodies that can interact with the process of blood clotting to cause the blood to clot more easily than normal. This is part of the immunologic abnormalities associated with lupus in some affected individuals. ...Read more
Agents which slow ;/or break down blood clot formation in up to 3 different ways (they do not decrease blood viscosity; thickness.) (1) some inhibit platelet function (e.g. Aspirin, clopidogrel, etc.). (2) others interfere with some of the clot forming proteins (warfarin, dabigatran, rivaroxaban, etc.), (3) others stimulate the blood clot destruction ...Read more
Impossible to say: It depends on many factors, not just on a diagnosis. If you are able to work, you are not disabled no matter what the underlying medical issues. ...Read more
No big deal usually.: Depending on whether you have a diagnosis of lupus or prior clotting problems, this may or may not be significant for your pregnancy. Studies show that most women with lac have normal pregnancies. Lupus anticoagulant (lac) is a laboratory finding and in and of itself not significant for predicting clinical outcomes. If you have systemic lupus erythematosus the plot thickens and you need to see mfm. ...Read more
I tested positive for lupus anticoagulant when I was pregnant but do not now. My brother has as and my son is + for hlab27. Should I get tested again?
Different things: The + hal b-27 not related to lupus anticoagulant(la). The la needs to confirmed, especially if you have a history of clinical problems related to the la like blood clots in the legs, emboli to the lung, strokes, misscarriages, etc. Depending on the clinical picture you may need therapy - many only Aspirin for its anticlotting ability or stronger blood thinners. ...Read more
I had 2 blood test that came back with lupus anticoagulant in feb 2012. I got told this won't affect me unless I get pregnant again is this true.
Can lupus anticoagulant be detected before a miscarriage occurs? Can you get rid of the anticoagulant?
Yes. Maybe.: Lupus anticoagulant can be diagnosed by a blood test, and in women with recurrent miscarriages, it can be treated with Heparin and aspirin. But not everyone with lupus anticoagulant has recurrent miscarriages. Some people may have natural protective factors. And most people with one miscarriage will have a normal work-up & normal next pregnancy. So we usually test for it after 2 miscarriages. ...Read more
I have had two miscarriages pcos thin. I tested positive for mthr-gene and lupus anticoagulant. Should i look at IUI next time? I get period 18 days
Before pregnancy!: Make sure that both you ; your hubby (if + for the mthfr 677 or 1298 genotypes), are first being treated with l-methylfolate, p5p, and methylcobalamin (at the minimum), to give any pregnancy a best chance for success. Also, do not take a prenatal vitamin that has regular fa if you are a known mthfr+ person. The regular Folic Acid blocks the receptors that need to let l-mthf through. Pm me! ...Read moreSee 1 more doctor answer
Clotting antibody: The lupus anticoagulant is a phospholipid antibody that can bind to cell membranes to make them sticky and increase the risk of blood clotting. It can occur transiently as the result of infections or medicines, or it can occur as spontaneous auto-antibodies or with autoimmune diseases. It may increase the risk of infertility or recurrent miscarriages. ...Read more
Not necessarily: Although many people with lupus have lupus anticoagulant not all do. And most people with lupus anticoagulant do not have lupus. Patients with lupus are more likely to develop the lupus anticoagulant than the general population so it is one "marker" for the disease. ...Read moreSee 1 more doctor answer
Anticoagulants are any of a variety of drugs which decrease the body's ability to make or sustain blood clots. They fall, generally, into two categories. Drugs like Aspirin and clopidogrel (plavix) prevent platelets from forming the initial stages of a clot. Drugs like warfarin (coumadin) and dabigatran (pradaxa) block the later process ...Read more
If your "lupus anticoagulant" test is positive, it indicates that your blood may clot more easily than it should (long story on the reason for the backwards name). It is important to know that this is only one of several tests for abnormal clotting that a person with an autoimmune ...Read more
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