Top
29
Doctor insights on: How Do Iga Nephropathy Patients Have Kidney Failure

Share
1

1
I was diagnosed IgA nephropathy since birth, and is weight loss a sign of pre-kidney failure?

I was diagnosed IgA nephropathy since birth, and is weight loss a sign of pre-kidney failure?

It can be.: Weight usually only occurs in the advanced stages of kidney failure. It frequently is associated with anorexia and avoidance of meat products. Have your basic blood checked soon. ...Read more

Kidney (Definition)

The kidneys are paired organs that lie on either side of the vertebral column. Part of their critical functions include the excretion of urine and removal of nitrogenous wastes products from the blood. They regulate acid-base, electrolyte, fluid balance and blood pressure. Through hormonal signals, the kidneys control the ...Read more


2

2
My 9 yr old son has strep throat and a kidney disease called IgA nephropathy it's a kidney disorder started when he was 5. Kidney biopsy?

My 9 yr old son has strep throat and a kidney disease called IgA nephropathy it's a kidney disorder started when he was 5. Kidney biopsy?

Confusing question: Although some strep strains can cause kidney problems, early treatment usually avoids them. If the kid has a pre-existing kidney problem, the need for a biopsy is best determined by the docs who know him best. A recent strep infection would not require such an invasive procedure, but a significant change in kidney function might. ...Read more

3

3
What are the chances that my kidneys will fail at some point because of my HSP and IgA nephropathy? Many thanks

What are the chances that my kidneys will fail at some point because of my HSP and IgA nephropathy? Many thanks

Renal failure: This is a guessing game I don't think you want to play. You are at increased risk with the IgA nephropathy but the HSP is transient. Just because you have increased risk does not mean it will happen. ...Read more

4

4
I have IgA nephropathy. I want to lose weight, will the Atkins shake do any harm to my kidneys?

I have IgA nephropathy. I want to lose weight, will the Atkins shake do any harm to my kidneys?

Limit protein intake: With IgA nephropathy, you may already have an abnormally high amount of protein in your urine which can lead to slow progressive kidney damage. A high protein diet (such as atkins) can result in even more protein leaking into your urine. Recommend limiting daily protein intake to 0.8 g/kg body weight and following up with your nephrologist for further advice. ...Read more

5

5
How can I have IGA nephropathy with daily microhematuria and proteinuria but a GFR of >90%. Doesn't hematuria always equal kidney damage?

How can I have IGA nephropathy with daily microhematuria and proteinuria but a GFR of >90%. Doesn't hematuria always equal kidney damage?

Not at all: Most patients with kidney disease have normal GFR. The estimated GFR on your lab slip is subscientific anyway. About 75% of IgA neohropathy patients have normal GFR and usually have little trouble. ...Read more

6

6
Colonoscopy next week. I was prescribed sodium phosphate. Safe to use when I have Iga-nephropathy (normal kidney function) and I am taking enalapril?

Colonoscopy next week. I was prescribed sodium phosphate. Safe to use when I have Iga-nephropathy (normal kidney function) and I am taking enalapril?

Phosphate laxative: Phosphate laxatives are generally not safe with any kidney disease, although your status of normal function is reassuring. Phosphate can surge in excess and crystallize in kidneys that are inflamed. Seek a different laxative. And, be sure you remain well hydrated as you prep for the colonoscopy. Dehydration is a major threat to your kidneys, too. ...Read more

7

7
What is a good diet for IgA nephropathy patients?

What is a good diet for IgA nephropathy patients?

Low antigen diet: Patients with IgAN have an immune problem. An Italian study by Ferri reported a marked reduction in proteinuria in IgAN patients put on a strict low-antigen diet (a diet free of foods likely to cause immune response- http://www. Ncbi. Nlm. Nih. Gov/pubmed/8302454). Such diets are low in wheat, soy, food preservatives, and food coloring. Contact Claudio Ferri Univ L'Aquila Coppito, Italy for more info ...Read more

8

8
What diet should a patient of IgA nephropathy follow?

What diet should a patient of IgA nephropathy follow?

Low protein is wise: However, if renal function is perfectly normal and you only have moderate protein losses in urine you may not need to restrict your protein intake. Fish oil is useful for IgA nephropathy, but you will be getting this in capsules. ...Read more

9

9
Can cessation of nicotine (not smoking, but NRT) reduce proteinuria in an iga nephropathy patient?

Can cessation of nicotine (not smoking, but NRT) reduce proteinuria in an iga nephropathy patient?

It is possible: nicotine is a very dangerous drug. For example, it has been shown recently in mice that it damages cells in the pancreas, why not in the kidney? ...Read more

10

10
How do ACE inhibitors work for treatment of Iga nephropathy where a patient already has normal blood pressure?

How do ACE inhibitors work for treatment of Iga nephropathy where a patient already has normal blood pressure?

Ace: Ace inhibitors block the angiotensin converting enzyme. This has an effect on the proximAl tube and glomerulus of your kidney. This benefits your kidney by not losing protein at these parts of the kidney. Good for your condition and diabetics too. ...Read more

11

11
What diet one should take if IgA nephropathy?

What diet one should take if IgA nephropathy?

Low-protein & salt: Nephropathy, kidney disease, regardless of cause, generally dictates a diet lower in protein and in sodium (table salt). The degree of restriction depends on the degree of current kidney compromise, the expectation of future damage, & the presence of other contributory risk factors like diabetes or hypertension. ...Read more

12

12
How would one go about getting IgA nephropathy?

How would one go about getting IgA nephropathy?

Sussceptibility: Iga nephropathy is a one of the most common glomerulonephritis ie a type of kidney disease in the world. The cause is not completely clear. Its a form of immunoglobulin ie a protein normally made in all of us, which gets deposited in the filter of the kidney, ie glomerulus and causes damage as it is slightly altered in those individuals. ...Read more

13

13
Can homeopathy cure IgA nephropathy?

Can homeopathy cure IgA nephropathy?

Not that is proven: No know therapy is shown to cure IgA nephropathy. ...Read more

14

14
I have IgA nephropathy and have had back pain. What should I do?

I have IgA nephropathy and have had back pain. What should I do?

Supportive care: Igan can cause sig back/flank pain. This may be unrelated to severity of disease (you may have severe pain but normal kidney function); treatment is challenging. Narcotics are addictive and will make you sleepy; nsaids (like ibuprofen) are toxic to kidney; tyelenol is safe but may not help. Try exercise/yoga/acupuncture/gabapentin/tricyclic anti-depressants. ...Read more

15

15
What are major symptoms of IgA nephropathy?

What are major symptoms of IgA nephropathy?

Blood in the urine: Iga nephropathy usually does not present with any noticable symptoms. However when you see your doctor, the doctor may notice blood in your urine. Also the doctor may notice protein in your urine. In some occassions, you may develop swelling in your feet. ...Read more

16

16
Is a biopsy necessary for IgA nephropathy?

Is a biopsy necessary for IgA nephropathy?

IgA Nephropathy: Urine and blood tests can be done but the only way for your doctor to confirm a diagnosis of IgA nephropathy is with a kidney biopsy. ...Read more

17

17
Is IGA Nephropathy genetic/hereditary?

Is IGA Nephropathy genetic/hereditary?

IgA neph: Data have shown a genetic clustering for IgA nephropathy - however its genetic nature is not certain - ...Read more

18

18
What is the treatment for proteinuria in IgA nephropathy?

What is the treatment for proteinuria in IgA nephropathy?

Proteinuria IgAN: Good question. Conventional approach is to commence an ACE Inhibitor and then titrate the dose upward slowly while measuring urine protein. Goal is to reduce proteinuria by at least 50%. Your BP program may require modification. Prednisone is also occasionally used for a flare of IgAN. ...Read more

19

19
I have IgA nephropathy, can I consume soy based proteins?

I have IgA nephropathy, can I consume soy based proteins?

Yes: Iga nephropathy is a immune mediated glimerulopathy. Fish oil is recommneded. Depending on kidney function you might need meds such as acei. You can take soy protein. ...Read more

20

20
What are IgA nephropathy or thin basement membrane disease?

What are IgA nephropathy or thin basement membrane disease?

IgA: Primary IgA nephropathy is the most common glomerulitis in the us. Most cases follow a slow path to renal compromise but many are more benign. Iga deposits are oalso seen secodnay to lupus, othe connective tissue disease, ankylosing spondylitis, henoch schonlein disease. ...Read more

21

21
Can someone with IgA nephropathy stage 2 take pure garcinia cambogia?

Can someone with IgA nephropathy stage 2 take pure garcinia cambogia?

I say yes: This is one of the herbals that might actually have a real effect as claimed; since the active ingredient is just hydroxycitric acid which so far as I know isn't a kidney poison, it should be fine for you. Check with your nephrologist also. ...Read more

22

22
Hi, I am on Micardis (telmisartan) plus 12.5/80 for my IgA nephropathy & hypertension once a day. Is there is any relation btwn this med and appetite?

Hi, I am on Micardis (telmisartan) plus 12.5/80 for my IgA nephropathy & hypertension once a day. Is there is any relation btwn this med and appetite?

Possible: I have never read or heard of Micardis (telmisartan) plus (telmistartan/hydrochlorothiazide) to cause changes in appetite. Zoloft definitely has an association with appetite changes. If you recently started either of these medications there is a small chance they could be interacting with another. Ask your primary care about changing the time of day you take these medicines. ...Read more

23

23
Diagnosed w/ IgA Nephropathy in 2006 & experience severe fatigue/almost constant malaise. Is this caused by IgAN? How do I monitor its progression?

Diagnosed w/ IgA Nephropathy in 2006 & experience severe fatigue/almost constant malaise. Is this caused by IgAN? How do I monitor its progression?

IgA nephropathy: IgA nephropathy itself does not cause fatigue or malaise, unless kidney impairment is progressing. Then, anemia will appear and the kidney impairment will also cause fatigue; Progression is monitored by serum creatinine, urine protein, and BP and blood albumin levels. ...Read more

24

24
I was diagnosed with IgA nephropathy two years ago an I have always been allergic to cold weather. I think it might be cold urticaria. What shall ido?

I was diagnosed with IgA nephropathy two years ago an I have always been allergic to cold weather. I think it might be cold urticaria. What shall ido?

Avoid cold: Do you get hives when you go out in cold weather or in cold water? (you can also leave an ice cube on your skin and see if a hive develops) treatment of this can be very challenging- some patients take antihistamines (benadryl, cetirizine, fexofenadine) but their value is unproven. Some (like my wife) simply avoid the stimulus (cold) and this is best but hard if you live where it is cold. ...Read more

25

25
I have IgA nephropathy and I want to lose weight. Is ok for me to drink shakeology?

Talk to renal doc: While I'm not specifically familiar with shakeology, many of those preparations contain quite high levels of proteins. This may be quite hard for your kidneys to handle if you have renal problems. It is going to make a difference how much renal function you have left, etc. Also, some of these products have higher levels of potassium, so that, too, may be tough on you. Share info with renal doc. ...Read more

Dr. Jay Park Dr. Park
1 doctor agreed:
26

26
I have HSP with IgA nephropathy and were put on 40mg prednisolone but has not worked and rash hasn't gone what treatment would be next? Regards

Dr. Jay Park Dr. Park
1 doctor agreed:

See below: Iga nephropathy is a part of kidney involvement in HSP (henoch-schonlein purpura). There is no specific treatment other than symptomatic relief. I wonder you have developed nephrotic syndrome which is not amenable to steroid treatment. We do know individuals with IgA nephropathy complicated by nephrotic syndrome has a poorer prognosis compared to one without. Long-term follow-up is needed. ...Read more

27

27
My otherwise healthy husband, 40, was diagnosed with IgA nephropathy. His doctor is recommending (though not strongly) prednisone for 6 months. Agree?

My otherwise healthy husband, 40, was diagnosed with IgA nephropathy. His doctor is recommending (though not strongly) prednisone for 6 months. Agree?

ACE-I, ARB initially: Kdigo guidelines:
we recommend long-term ace-i or arb
treatment when proteinuria is >1 g/d, with
up-titration of the drug depending on blood
pressure. (1b)
we recommend long-term ace-i or arb
treatment when proteinuria is 41 g/d, with
up-titration of the drug depending on blood
pressure. (1b)
: we suggest that patients with persistent
proteinuria z1 g/d, despite 3–6 months of
optimized supportive. ...Read more

28

28
How many people are suffering from IgA nephropathy disease in Canada? (%) Thank you for your time. :)

How many people are suffering from IgA nephropathy disease in Canada? (%) Thank you for your time. :)

Hard to tell: There are some incidence reports for several countries, but didn't see a report for Canada. Canada may be in the low end of the range of about 15-40 new cases per million people per year. That would be ~525 new cases per year, for Canada's 35 million people. The prevalence number is the number of total living patients with it, not just the annual new cases (Ministry of Health may know the number). ...Read more

29

29
What is the life expectancy after being diagnosed with IgA nephropathy?

What is the life expectancy after being diagnosed with IgA nephropathy?

Not short.: Iga nephropathy sometimes resolves spontaneously. Many cases have stable disease i.e. With no deterioration for long years. Severe cases however, will develop end-stage renal disease and require dialysis. They will be eligible for transplant that can be repeated if needed. Each transplant could give on the average 90%+ of 10-15 years renal graft survival. ...Read more

Dr. Tarek Naguib
603 Doctors shared insights

Kidney Failure (Definition)

A condition in which your kidneys suddenly stop working normally. Since your kidneys remove waste products and help balance water and salt and other minerals (electrolytes) in your blood, when your kidneys stop working, waste products, fluids, and electrolytes build up in your body. This can cause problems ...Read more


Dr. Eric Weisman
104 Doctors shared insights

Nephropathy (Definition)

Nephropathy is a medical term that refers to disease of the kidney. There are many causes. It can be caused by high blood pressure, diabetes, uric acid, abnormal proteins, cancers, blood vessel blockages in the kidney, it can be minimal or or it can be severe ...Read more