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Doctor insights on: How Do I Know If I Have A Genetic Predisposition To Bipolar Disorder

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How do I know if I have a genetic predisposition to bipolar disorder?

How do I know if I have a genetic predisposition to bipolar disorder?

Family History: If you have a so-called first-degree relative (sibling, mother, or father), with bd your genetic "loading" for bd is higher than if you don't. However, lots of people have bd with no known family history; and, even if both your mother and father have bd, the risk that you will too still is only about 20%--way higher than the general population but not a sure thing. ...Read more

Dr. Alan Ali
1,717 doctors shared insights

Bipolar Disorder (Definition)

Also known as manic-depressive illness, bipolar disorder is a brain disorder that in its most severe form causes dramatic shifts in mood, from mania to depression. Symptoms of mania include markedly elevated mood and energy, reduced sleep and a reduced need for sleep, racing thoughts, and grandiose ideas. When mood changes are severe, psychotic ideation may be present. Symptoms of depression can include low energy, feeling sad, feelings of guilt and hopelessness that are out of proportion to the patient's actual situation, low motivation, inability to experience pleasure, and suicidal ideation. Sleep may be increased, and concentration may be impaired. Some manic patients may be extremely irritable rather than euphoric. Less severe but clearly abnormal mood ...Read more


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Could i be born with a genetic predisposition to bipolar disorder?

Could i be born with a genetic predisposition to bipolar disorder?

Yes: There's an incompletely understood genetic connection in bipolar disorder. The most convincing evidence is studies of monozygotic twins, in which there's increased likelihood of bipolar disorder in both twins if one presents with this disorder. Children of bipolar parents are at higher risk than others, of developing a mood disorder. Growing up with a bipolar parent brings risks also. ...Read more

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Is it possible to test to see if you have a genetic predisposition for bipolar disorder?

Is it possible to test to see if you have a genetic predisposition for bipolar disorder?

Nospecific test: There is not a specific test for this. However, a strong family history of mood disorders including bipolar disorder would increase odds. ...Read more

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Are there different forms of severity in bipolar disorder? And can it be genetic?

Are there different forms of severity in bipolar disorder?  And can it be genetic?

Yes, there are: Different forms and severity, and even cycling speed, of bipolar disorder. Some folks are more manic and some more depressed. While we are making strides w/neuroscience, we don't know the exact cause and why some folks have more pronounced symptoms than others. Peace and good health. ...Read more

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Which type of genetic disorder is bipolar disorder?

Which type of genetic disorder is bipolar disorder?

Genetics of Bipolar: Although results inconsistent, many earlier studies suggest chromosomal aberrations (specifically chromosome 6q & 8q21). Most studies suggested heterogeneity (several genes involved, specifically those for serotonin, Dopamine & glutamate. Also, there is strong correlation with advanced paternal age, suggesting genetic mutations. ...Read more

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I need to find dr who understands the correlation between bipolar disorder and drugs?

I need to find dr who understands the correlation between bipolar disorder and drugs?

That's a shame: You need to try and find either a board certified addiction psychiatrist or a board certified psychiatrist who is also board certified in addictionology (like me). I think that drugs of abuse most certainly makes bipolar d/o worse and those with bipolar d/o suffer from a greater risk of substance abuse and dependency. I treat both at the same time in my clinic. You should be able to find someone. ...Read more

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What is bipolar disorder and the symptoms? How do I know if I have it?

What is bipolar disorder and the symptoms? How do I know if I have it?

Bipolar: Either manic phases alternating with depressed episodes, each lasting @2 weeks, or rapid cycles where moods alternate day in & day out. ...Read more

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How do I know if I have ADHD or bipolar disorder?

Could be both: Adhd & bipolar disorder are conditions that require expert intervention for diagnosis & treatment. A person could have either or both at the same time (comorbid conditions). Bd are usually more rageful, irritable, aggressive & angry. Bd folks cycle through moods such as depression or extreme happiness (euphoria or mania). Adhd folks tend not to be that way. ...Read more

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How do I know if I have depression bipolar disorder?

How do I know if I have depression bipolar disorder?

Bipolar: Bipolar I and bipolar II, In the first, manic phases are more severe, and in the second, depressive phases are more severe. There is also cyclothymia which is a low grade version of bipolar disorder in general, where mood swings are not as severe in either direction, manic or depressive. Get a full psychiatric evaluation for what bothers you and ask for a referral to a reputable psychotherapist. ...Read more

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Genetic (Definition)

From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more


Dr. Donald Jacobson
737 doctors shared insights

Manic Depressive Disorder (Definition)

Though depression is not required for diagnosis most people have both manic and depressive episodes and may have mixed episodes with features of both. Length of episodes vary, but are separated by "normal" periods of emotion and behavior. See my answers to similar ...Read more