Doctor insights on:
How Do Ace Inhibitors Work
How do ACE inhibitors work? How is it that they lower vascular resistance yet cardiac output, rate and contractility are the same?
Blood Pressure: Meds: Ace inhibitors block the conversion angiotensin i to angiotensin ii, which constricts the vessels, increases the following: salt retention in the kidney, sympathetic tone, aldosterone and ADH (vasopressin) (anti-diuretic hormone) secretion. The inhibition of this conversion decreases blood pressure and wall stress in the heart muscle. ...Read more
Vasodilators: They dilate blood vessels.Get a more detailed answer ›
Heart and kidney: Ace inhibitors are blood pressure medications used for blood pressure treatment. They also have effects independent of the blood pressure effect on the heart, particularly for people with heart failure, and on the kidneys, particulaly for people who have diabetic-induced kidney disease with protein in the urine. ...Read more
No: There is a common misconception that calm people don't have hypertension and treating antihypertensives will calm people. Overall that is not the case. There may be one exception.Beta blockers block adrenaline which can make one feel calmer. Acei other antihypertensives usually do not result in people feeling calmer. ...Read more
Ace vs arb: They are drugs which block functions at different points in the same pathway. Ace blocks an enzyme and arb blocks a receptor, their effects are similar. It's something like either cutting a wire to a spark plug or damaging the plug itself. Either way you don't get a spark. ...Read more
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