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Doctor insights on: How Common Is The Sickle Cell Disease Trait In America

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How common is the sickle cell disease trait in america?

How common is the sickle cell disease trait in america?

8-10%: The prevelance of sickle cell trait in african americans is thouight to be about 8 to 10 percent. It may be as high as 25 to 30 percent in certain parts of western africa. ...Read more

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Dr. James Ball
348 doctors shared insights

Sickle Cell Disease (Definition)

This is a genetic disorder in which hemoglobin is abnormally made., more common in people of african descent. This abnormality causes red blood cells to become stiff and fall apart. This can cause very specific symptoms: pain, pneumonias, strokes, spleen problems, and many other problems. Some have mild disease, some ...Read more


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If my boyfriend has sickle cell anemia and I don't have neither the trait or disease, will our child end up having it?

If my boyfriend has sickle cell anemia and I don't have neither the trait or disease, will our child end up having it?

No: If your boyfriend has sickle cell anemia (2 abnormal genes) and you have 2 normal genes, then your children will all have sickle cell trait but none will have the disease. You need to be sure you have no other blood abnormalities like thalassemia or hemoglobin c trait which can be totally asymptomatic; this would change the answer significantly! ...Read more

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What type of genetic disorder is sickle cell anemia or trait?

What type of genetic disorder is sickle cell anemia or trait?

Hemoglobinopathy: Patients with sickle cell anemia make an abnormal hemoglobin (hgb.). Normal HGB consists of paired protein chains (globin) and an iron containing part (heme). Patients with ssa inherit an abnormal beta-globin gene from each parent. Carriers have one normal beta-globin gene and one sickle beta globin gene. The carriers (trait) have no symptoms. ...Read more

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What is the cause of sickle cell disease and trait?

What is the cause of sickle cell disease and trait?

Gene mutation: Sickle cell trait is caused bu the presence of a single mutation in the beta chain of human hemoglopin a gene. A mutation in one gene on one of a person's two beta globin genes results in sickle cell trait (sa hemoglobin) while the same mutation in both of a persons genes causes sickle cell anemia. (ss hemoglobin). The term trait means a carrier for the sickle cell mutation. ...Read more

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My spouse is a carrier of the trait but I am not. What are the chances of our kids having sickle cell disease?

My spouse is a carrier of the trait but I am not. What are the chances of our kids having sickle cell disease?

None: If you know for sure that you are not a carrier of the trait, your child will not have sickle cell disease. However, you have a 50% chance of having a child with the trait. The good news is that people with the sickle cell trait usually have very few (or no) medical problems. ...Read more

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What difference between sickle cell trait & disease?

Severity: The trait alone does little to the person, the sickle cell disease is very debilitating on most patients. ...Read more

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What is the difference between sickle cell trait & sickle cell disease?

What is the difference between sickle cell trait & sickle cell disease?

Carrier vs. Affected: Sickle cell trait denotes being a carrier while sickle cell disease is someone who has the disorder. Sickling requires 2 genes. A person with the s gene and a normal gene would be a carrier and considered to have sickle cell trait. Someone who has s and s would be considered to have sickle cell disease and would likley be affected. ...Read more

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If I have sickle cell trait but not disease will I need to do anything special on long flights?

If I have sickle cell trait but not disease will I need to do anything special on long flights?

No: It is always a good idea to get up and walk around a little bit on long flights, as the flights themselves increase the risk of getting a clot in the legs (lower extremities). However the sickle cell trait does not place you at any higher of a risk for a venous clot than the general population. ...Read more

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If me and my partner has sickle cell trait, does this mean my child will surely get the disease?

If me and my partner has sickle cell trait, does this mean my child will surely get the disease?

Not necessarily: If you and your partner both have sickle cell trait, there is a 25% chance your child will be normal (not have sickle cell trait or anemia), a 50% chance they will have sickle cell trait (just like you and your partner), and a 25% chance they will have sickle cell disease. Prenatal diagnosis is available early in pregnancy that will tell you what your child has. ...Read more