Doctor insights on:
How Can The Cystic Fibrosis Gene Affect Tuberculosis
Lung Function: The gene itself will not affect tuberculosis. However, if an individual receives 2 recessive genes of the cftr mutation from their parents, they will develop cystic fibrosis (cf). Because CF can lead to repeated bacterial lung infections (among other things), the lungs would already be in a weakened state if exposed to the causative agent of tuberculosis. This might lead to faster disease onset. ...Read moreSee 1 more doctor answer
From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more
What are the overlapping features of cystic fibrosis and tuberculosis, as revealed by chest x-ray? Responding in technical language is fine.
What are the chances of passing on the Cystic Fibrosis gene if only one parent is a CARRIER? Other parent not a carrier.
50-50: One half of offspring will be carriers and one half will not be carriers. No offspring will be afflicted. Thanks for trusting HealthTap! ...Read more
Autosomal recessive: CF is an autosomal recessive genetic disorder. Complete expression of the disease (symptoms) do not typically occur in people who do not have both copies of the defective gene (carriers only have one). ...Read more
Is there a resource out there that discusses the different cystic fibrosis gene mutations & which symptoms are associated with each one?
CF resource: http://www.cff.org/ Try this one!Get a more detailed answer ›
CF gene mutations: There are currently more than 1900 mutations that are known to cause cf. About 70% of CF pts in us have deltaf508 mutation, as 1 in every 25 persons is a carrier for this mutation. All these mutations result in abnormal activity of a protein called cftr which causes all the CF related problems. Genetic testing can give the specific mutation each pt has. Talk to your local CF center. ...Read more
Yes: It is a recessive trait, so both have to have the gene to pass it to a child. ...Read more
Mycobacterium tuberculosis is an infectious organism that spreads by droplets coughed out by an infected person. Infection is established initially in lungs, but can spread within lungs & to other body parts, or can become latent, with reactivation occurring years to decades later. With effective treatment, it can be completely eliminated although drug resistant ...Read more
Is an infection in the body with mycobacterium tuberculosis. It is almost always acquired via the respiratory tract from which it can spread to other organs. After that, the immune system walls the bacteria off. All of this usually occurs without symptoms. After that, activation of the infection can occur in about 10% of the total patients. Half of this risk is in ...Read more
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