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Doctor insights on: How Can I Have A Sickle Cell Crisis Without Having The Disease

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How can I have a sickle cell crisis without having the anemia?

How can I have a sickle cell crisis without having the anemia?

I dont think you can: Sickle cell crisis only happens if you have a diagnosis of sickle cell anemia. The degree of anemia sometimes is not that severe-however you will have anemia if you have sickle cell disease - not just a trait. If you only have a sickle cell trait -you will not have a sickle cell crisis. ...Read more

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Dr. Mohammed Parvez
43 doctors shared insights

Sickle Cell Crisis (Definition)

A painful episode that occurs in people who have sickle cell anemia. It happens when sickle-shaped red blood cells block blood vessels. Blood and oxygen cannot get to ...Read more


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I was wondering how I could have a sickle cell crisis without having the disease?

I was wondering how I could have a sickle cell crisis without having the disease?

Not typically: If you have the sickle cell trait, it is possible to have an anemic crisis in the setting of severe dehydration or stress to the immune system, though this is rare. In most cases, individuals with the sickle cell trait live perfectly healthy lives. Remaining hydrated especially in the setting of physical activity and excessive heat should help to prevent any symptoms. ...Read more

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Is anemia always present in sickle cell anemia? And for how long can i experience pain without this being a crisis for sickle cell?

Is anemia always present in sickle cell anemia? And for how long can  i experience pain without this being a crisis for sickle cell?

They call it sickle: Cell anemia because, indeed, patients essentially all have anemia. The anemia actually improves the rheologic (flow) properties of blood in these patients, whose rbcs are otherwise rigid with reduced degrees of freedom for deformability. Sickle cell pain occurs due to microvascular occlusion and tissue compromise. Oral opiates/ nsaids may provide relief, but IV opiates may be needed (pain crisis). ...Read more

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Can a sickle cell patient get crisis when having sex?

Can a sickle cell patient get crisis when having sex?

Probably: We do not fully understand all of the causes of sickle cell pain crises. Dehydration and acidosis are tow known contributors. Physical exertion can lead to dehydration and acidosis, so to the extent that sex can be physically exerting, a patient may get a crisis with sex. ...Read more

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What to do if I have to do a report on sickle cell anemia and I was wondering do people with sickle cell anemia usually get splenectomies?

What to do if I have to do a report on sickle cell anemia and I was wondering do people with sickle cell anemia usually get splenectomies?

No: The disease usually results in the self destruction of the spleen as a functional organ by the age 3. At that point it would have no impact on the disorder and cease to be of any importance. ...Read more

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How likely am i to have sickle cell disease?

How likely am i to have sickle cell disease?

Impossible to say: Without knowing anything about you, i can't say how likely. Any symptoms previously or family history? If not, much less likely. Ancestors from africa or around the mediterranean? If not, much less likely. Were you born in a state after they had required screening for sickle cell? If yes and your parents were notified that your screen was normal then you don't. I can't help much more than that. ...Read more

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How could 2 people without sickle-cell anemia to have a child with sickle-cell disease?

How could 2 people without sickle-cell anemia to have a child with sickle-cell disease?

Genetics: Sickle cell disease must be inherited from both parents. Sickle cell trait (1 sickle gene, 1 normal gene) is usually asymptomatic. 2 persons with sickle cell trait have a 1/4 chance of having a child with sickle cell disease, but the parents are often unaware that they have anything. ...Read more

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If you have only the sickle cell trait, can you sometimes suffer like a person who has the disease?

If you have only the sickle cell trait, can you sometimes suffer like a person who has the disease?

On rare occasions: People with sickle cell trait under normal conditions (climate, altitude, normal life style) do not have any symptoms of sicle cell disease. Very occasionally individulas who had severe stressful conditions (boot camp under extreme heat and with dehydration), or worked under significanly reduced oxygen pressure (high altitude) did experieince vaso-occulsive crisis. Or had sudden death. ...Read more

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I have had sickle cell crisis frequently for the last 2 years, is there any tips on how i can manage the anaemia better. Thanks?

I have had sickle cell crisis frequently for the last 2 years, is there any tips on how i can manage the anaemia better. Thanks?

Hematologist: You need to be on folic acid. I would consider Hydroxyurea to try and reduce crisis episodes. However, you need to see a hematologist who takes care of a lot of sickle cell patients. Hope this helps. ...Read more

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I have sickle cell trait,am I at more of a risk for blood clots or embolism? If so how can I prevent them?

I have sickle cell trait,am I at more of a risk for blood clots or embolism? If so how can I prevent them?

Minor risk: Your greatest danger comes from non-pressurized aircraft and anything else that lowers your oxygen tension substantially. You also need to know that you can't concentrate your urine and retain your sodium as well as other folks, so be careful exercising in the heat. The increased thrombus risk is minimal. Keep your legs active especially on long plane flights. ...Read more

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I have sickle cell disease. If I contract fifth disease can there be complications?

I have sickle cell disease.  If I contract fifth disease can there be complications?

Yes: Aplastic crisis, profound dropping of hemoglobin (so called iron count) due to suppressed red cell production from bone marrow is a well known complication. ...Read more

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How do I prevent a crisis in flying with sickle cell anemia?

How do I prevent a crisis in flying with sickle cell anemia?

Sickle cell anemia: Good hydraion and good control/follow up wi your docor for your sickle cell are important. Your risk obviously will depend on the type of sickle cell anemia, the severity and your compliance to the therapy given for your sickle cell anemia. D/w your md and follow the recommendation. In general, need to keep good hydration, oxygenation. Take your Hydrea (hydroxyurea) as recommended and f/u with your doctor. ...Read more

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Hi, I have sickle cell anemia I wanted to know What are the risks in having a stem cell transplant done?

Hi, I have sickle cell anemia I wanted to know What are the risks in having a stem cell transplant done?

Major undertaking: Stem cell transplants are as major an undertaking as anyone can ever do. The process involves wiping out all of your existing blood forming centers and natural immunity. You are given stem cells that you hope will replace the ones you wiped out and start building new blood free of the sickle cell gene. Risks include catastrophic infection,failure of the transplant. Consult a SS center for details ...Read more

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Is it possible to be diagnosed with sickle cell anemia at 43? Even without ever experiencing any symptoms of the disease?

Is it possible to be diagnosed with sickle cell anemia at 43?  Even without ever experiencing any symptoms of the disease?

Possible, but...: Most people will have symptoms of enough severity to be diagnosed before adulthood. That being said, there is variation in the severity of sickle cell disease, most likely due to a number of other genes that modulate the symptoms. Thus, it probable is quite rare, but there could be that individual with a particular genetic makeup that has minimal disease that goes undiagnosed. ...Read more

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What will happen if I fly without extra o2 and I have sickle cell disease?

What will happen if I fly without extra o2 and I have sickle cell disease?

Ask ur Hematologist: Contact the airline company. They may be able to provide you with the oxygen while flying. You and your dr. Must fill out a medical form for that purpose. The fear in sicle cell is to have a crisis with severe pain and occlusion to the arteries causing strokes and heart attacks. ...Read more

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Do people with sickle cell crisis have a lot of pain?

Do people with sickle cell crisis have a lot of pain?

PAIN WITH SICKLECELL: Sickle cell disese is a painful conditon and can have hemolytic crises, sequestration and thrombotic crises.The thrombotic crises is the one which causes the pain in any part of the body.They can be extremely painful requiring narcotics and some times have to be admitted to the hospital for IV fluids and pain medications. ...Read more

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How probable am i to have sickle cell disaese?

How probable am i to have sickle cell disaese?

Impossible to say: Without knowing anything about you, i can't say how likely? Any family history? If not, much less likely. Ancestors from africa or around the mediterranean? If not, much less likely. Were you born in a state after they had required screening for sickle cell? If yes and your parents were notified that your screen was normal then you don't. I can't help much more than that. ...Read more

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If I have sickle cell disease, and my spouse doesn't, will our child have the disease?

If I have sickle cell disease, and my spouse doesn't, will our child have the disease?

Depends: If you have ss disease all of your potential kids would at least be a carrier(trait). If your spouse is a carrier ( some do not know) then your kids could be either carriers(trait) or affected. ...Read more

Dr. James Ball
355 doctors shared insights

Sickle Cell Disease (Definition)

A group of disorders that cause red blood cells to become ...Read more