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Doctor insights on: How Are Recombinant Clotting Factor Products Produced

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How are recombinant clotting factor products produced?

How are recombinant clotting factor products produced?

Bacterially, by DNA: Recombinant = dna plasmids are inserted into escherichia coli bacteria to have them make the clotting factor products. ...Read more

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Dr. Marvin Ott
6 doctors shared insights

Clotting Factors (Definition)

In cases of severe bleeding during delivery, blood transfusions or other clotting ...Read more


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What is a recombinant clotting factor product?

What is a recombinant clotting factor product?

Ultra High Tech!: These products(which are used to treat a wide variety of bleeding disorders like hemophilia, and von willebrand's disease) are made either by being completely free of human plasma derivative; or use a pasteurized form that is very safe. These products are not without there share of risks; and can potentially cause diseases as well. They are also very, very expensive so let the buyer beware! ...Read more

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Anything serious involved with the clotting factors?

Anything serious involved with the clotting factors?

It's all serious.: There is nothing funny about an unintended clot! not sure exactly what the question is. There are many diseases both inherited and acquired of the clotting factors and related proteins. ...Read more

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I know they're basically all important but what would you say is the most important clotting factor to have in the blood?

I know they're basically all important but what would you say is the most important clotting factor to have in the blood?

Meaningless question: If you were given this as a homework assignment, contact the teacher's supervisor. "Which is more important, your car's motor or chassis or steering system?" Fibrinogen actually forms the clot. This may be what the teacher wants you to say. It will only be activated by thrombin, derived from prothrombin. There are a host of others, many of which are lethal if genetically absent. ...Read more

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What is a clotting factor deficiency in a child?

What is a clotting factor deficiency in a child?

Depends on which : Factor. There are about a dozen clotting factors and any of those could be deficient. Some are serious others not so much. It is not feasible to provide specific suggestion from the information provided. ...Read more

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Does high mpv effect blood clotting factor?

Does high mpv effect blood clotting factor?

no: No it can be normal or reactive if rest of the blood counts are normal nothing to worry about. ...Read more

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I had taken a clotting factor 2 months back due to excessive bleeding, and now my periods are late for about 3 weeks. Should I worry?

I had taken a clotting factor 2 months back due to excessive bleeding, and now my periods are late for about 3 weeks. Should I worry?

Clotting factor?: It is to clear what you mean by clotting factor. If you have a clotting disorder such as Von Willebrand’s disease then it is likely that lifetime treatment will be needed. Contact your doctor for clarification on your diagnosis and the long term treatment plan. If you think you might be pregnant check then check a home pregnancy test. They are cheap, reliable and available at any pharmacy. ...Read more

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Does having lots of nosebleeds mean some sort of clotting factor deficiency?

Does having lots of nosebleeds mean some sort of clotting factor deficiency?

Not necessarily: There can be various local reasons in the nose that can cause recurrent nosebleeds. If you bruise easily, have bleeding gums, or have heavy periods in association with recurrent nosebleeds, you may have a blood disorder. Your ENT and primary care doctor along w/ a hematologist may all need to work together to help diagnose this disorder. ...Read more

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Was taking a recombinant-derived fviii for hempohilia a and inhibitor appear. Finishing iti and doc says 2 try plasma fviii. Alphanate (factor viii and von willebrand factor) or koate and y?

Follow his advice: Development of recombinant factor v111 inhibitor those occur frequently after prolonged treatment and those make the treatment less effective. Hence your dr will recommend products to bypass the inhibition. ...Read more

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What is the significance of recombinant insulin?

What is the significance of recombinant insulin?

It was a: significant medical development, making purer, better, more natural, safer insulin readily available rather than having to rely on animal sources. ...Read more