Doctor insights on:
Hormone Therapy Prostate Cancer
Treatment: Hormone therapy consists of medications that decrease the effects of testosterone on prostate cancer and a man's body. Prostate cancer growth is primarily fueled by testosterone. If testosterone is absent/ineffective, prostate cancer hopefully would stop growing. Hormone therapy has several varieties including pills and injections. Given for advanced disease or at times prior to radiation. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
I want to know for how long should I take hormone therapy for prostate cancer after taking radio therapy?
Discuss w urologist: No advice can be given without knowing stage & grade (requires result of prostate biopsy) of your prostate cancer. Was there any consideration of surgery before radiation? . What kind of hormone therapy are you receiving, estrogenic or anti-androgen? . Has there been consideration of castration surgery. Best advice is from a uro-oncologist ...Read more
Generally - No: Hormone blockade (hb) can cause many problems but they tend to be time related. The longer on hb the more the problems. Hb often makes pre-existing problem worse or accelerates some problems. Hb itself rarely causes "confusion", more often it can cause depression, fatigue, and emotional changes. Only older men on hb for a very long time tend to have true cognitive dysfunction. ...Read more
It can.: Androgen deprivation therapy (adt), or hormonal therapy for prostate cancer, seeks to eliminate androgens like testosterone which can be fuel for prostate cancer cells. Eliminating these hormones can have a major effect on sexual function, such as decreased libido and erectile dysfunction. ...Read more
It depends: First we need mor einformation: is this question for you or someone else? How old is the pperson in your question. Testes are temporarily suppressed if you take reversible hormonal therapy like with the GNRH agonist injections. ...Read more
Yes, rarely: For the most part, the hormone blockade would not cause confusion. The hormone blockers can make any pre-existing condition gradual worse but they are also reversible. That said, after giving this therapy to >1000 men, only once have I seen someone with pre-existing mental disease have serious rapid worsening. This was fixed by stopping the hormone blockers. ...Read more
Tradeoffs: Hormone therapy as it is called is actually the process of reducing male hormone levels either chemically or surgically. It is highly effective as a means of controlling prostate cancer, but long term use can cause reduced bone mass, weight gain and possibly cardiovascular side effects. Without the therapy however, there would very likely be more severe possibly lethal prostate cancer issues. ...Read more
It can be.: Androgen deprivation therapy (adt) is used in the treatment of advanced prostate cancer. Though is can slow progression of the disease, it is associated with significant side effects such as bone loss, muscle loss, loss of libido, and possible increased cardiovascular risk. Intermittent hormonal therapy is now under investigation, as are agents to counteract some of the side effects. ...Read more
Looking an alternative for hormone therapy. Operated on in 2002 for prostate cancer....psa level is at 4 from 1.5 3 years ago.
Better ask: Your oncologist, s/he would be the best to answer your queries in context of your history and clinical exam, unfortunately there is no generic answer, wish you well ...Read more
Having advanced prostate cancer and on hormone therapy. How long a wait till tumor shrinks to a workable size does 8 months sound?
Prostate ca: What do you mean by workable size? The response to therapy-. In this case- hormonal therapy will be individually basis. Majority'll respond well and you can see this by following your psa as the level will go down. Now how long it will take to become normal- it varies, and will depend on the tumor burden. Some imaging like a bone scan or ct scan periodically can be used to monitor the response as well. ...Read more
My dad has spine metastes frm primary prostate cancer, terminal, indefinate hormone therapy...Whats average prognosis please?
Depends how long: How long on hormones? If just started the cancer may respond for average of several years. If he was already on hormones for long time prognosis is worse months to a year or two using other option such as different drugs or chemotherapy. Not cureable at this point just delaying progression. Some are offering Provenge (sipuleucel-t) but it's new and not known how effective, this is a vaccine type of therapy. ...Read more
Dad is 68, recently diagnosed with advaced prostate cancer with skeletal bone metastasis. What kind of hormone therapy shall he use?
Surgical vs medical:
There are 2 ways to address this.
Surgical castration with bilateral orchiectomy is a good option with a one time surgery and good relief.
Medical castration ie combined androgen blockade is done with Casodex and Lupron (leuprolide) (expensive and need to be given at periodic intervals. Talk to your oncologist and see how your father wishes to proceed. Palliative radiation is a good option for bone pain. ...Read more
My dad is 68 years old. Recently, he was dignosed with advanced prostate cancer with skeletal bone metastasis. What kind of hormone therapy shall he use? Is orchiectomy ok?
Orchiectomy OK but: The standard of care is an lhrh agonist (such as lupron, zoladex) injection combined with a drug taken by mouth called casodex. The Casodex should be used for a minimum of 1 month and then can be stopped. The advantage is that these injections can be as little as once every 6 months. Alternatively, a drug called Firmagon (degarelix) (an lhrh antagonist) can be given monthly without the casodex. ...Read more
It's been six years since my dad has had prostate cancer. He has had radiation and hormone therapy. Now his gleason numbers are high now spots on spin. What doesit mean?
May have returned: Unfortunately this may mean that your father's cancer has progressed despite treatment. A high gleason score (8-10) independently predicts the odds of this as well as high psa score and abnormal exam findings. Fortunately there are many highly effective treatments available even in situations where the cancer has spread. An oncologist can help you decide on appropriate treatments for your father. ...Read more
Good evening, pt with prostate cancer & TURP done for him in 2010 & now on hormonal therapy but the tpsa level increased > 70. Why? What to do? Thanks
Biochemical relapse: Most likely this is a case of biochemical relapse. However, metastatic disease should be ruled out (ct scan, bone scan). If there is no site of metastatic disease- then it is biochemical relapse. Then in that case, he should see a radiation oncologist for local radiation to the prostatic area, in addition to hormonal therapy. Discuss further with oncology team. ...Read more
Following hormone treatment for prostate cancer all clear. How long do the hormones stay in your body?
Depending. ..: Glad to hear getting favorable response to hormonal manipulation for prostate cancer. The duration of its level may widely vary reflecting the pharmacological formulation for drug release in the body, personal hepatic function, etc. How long may its clinical effect last? It is also widely vary reflecting the coping ability of cancer, health, etc. May hold. More? Ask urologist or medical oncology. ...Read more
My dad has recently been diagnosed with prostate cancer they said they can not cure it but use hormone treatment. He's 70 yr old. How long he got?
My dad 70 yr old has prostate cancer gleason 9 which has metastised. He has no pain and is on hormone treatment. Can he survive for more than 3 yrs?
Yes: About 50% of men live 5 years after they diagnosed with metastatic prostate cancer. This is improved from even 10 years ago when only about 30% of men lived 5 years. There are many new treatments available including new hormonal agents, chemotherapy, immunotherapy, and targeted radiation therapy that can extend survival and quality of life even after standard hormone therapy stops working. ...Read more
Does a person with a prostate cancer gleason score of 9 have any shot? Dr states hormone rherapy and possible radiation depend on ct/mri & bone scan
My father diagnosed with prostate cancer he is having the hormonal treatment. He is 78, dr. Say it's localized in the prostate and litlle spot in the bone around, is that means it spread and no hope or he have the chance to live longer
Possibly, not typical: The uterus is at risk for precancerous changes or uterine cancer when estrogen is taken without progesterone. This is called unopposed estrogen. After a hysterectomy, no Progesterone is needed. Studies on breast cancer & hormone replacement remain controversial, but most evidence points to Progesterone as the culprit in breast disease. Stay posted as more knowledge about this topic changes often. ...Read more
Depends on situation: If you are receiving hormonal therapy for metastatic breast cancer you will hopefully notice improvement in symptoms from the cancer or by seeing an improvement on another scan. If you are taking hormonal therapy to minimize the chance of recurrence, there is no way to know how well it is working for you as an individual. However, many studies prove that it decreases the chance of recurrence. ...Read more
Very low Risk: With due respect. The landmark study, whi, is called into question in so many ways. The nih spent millions to answer very little. As an re, I feel there are many facets to HRT and a careful and comprehensive evaluation of the literature supports a very minimal at best increase in breast cancer and the evidence points to the progestin component only (provera). Consultation warranted. ...Read more
NO BUT INCREASE RISK: Hormone therapy does not cause breast cancer but it does increase your risk of breast cancer. According to the national nurses health study using hormone replacement therapy for 10-15 yrs increases risk about 20%, if used more than 15 yrs it doubles to around 40%. Talk to your doctor to help you decide how to better manage postmenopausal symptoms. ...Read more
Yes: Certain hormones, especially longer use of estrogens, can increase a person's risk of breast cancer. Estrogen is listed as a known carcinogen on the fda web site & there is a class action lawsuit ongoing against premarin (conjugated estrogens). See site: http://m.Cancer. Org/cancer/cancercauses/othercarcinogens/generalinformationaboutcarcinogens/known-and-probable-human-carcinogens. ...Read more
If I live beyond 5 years with bone only metastatic breast cancer, how long can the hormone therapy be taken?
The prostate is a gland that lies at the base of the bladder and surrounding a segment of urethra. It secretes a milky fluid that is discharged by excretory ducts into the urethra during the emission of semen. It is clinically important because enlargement of the prostate with age, and prostate cancer are two common ...Read more
A hormone (from greek ὁρμή, "impetus") is a chemical released by a cell or a gland in one part of the body that sends out messages that affect cells in other parts of the organism. Only a little amount of hormone is required to alter cell metabolism. In essence, it is a chemical messenger that transports a signal from ...Read more