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Doctor insights on: Hormone Sensitive Breast Cancer

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Dr. Liawaty Ho Dr. Ho
4 doctors agreed:
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Chemotherapy hormone receptor positive node breast cancer?

Dr. Liawaty Ho Dr. Ho
4 doctors agreed:
Chemotherapy hormone receptor positive node breast cancer?

D/W oncologist: Treatment will depend not only the stage but also the biology of the cancer- whether it is estrogen positive, her2neu positive, whether it is lymph node positive or not. Also depends on your preference and overall health condition. Different test like oncotype dx, mammaprint can give you more info-re- recurrence risk of cancer and will be helpful in choosing the right therapy for you.D/w your md. ...Read more

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Dr. Barry Rosen
4,368 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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What is estrogen receptor positive breast cancer?

One with receptors.: These are tumors with estrogen receptors on them. This makes them susceptable to some chemotherapeutic agents, like tamoxifen. ...Read more

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Could premerin homone replacement cause Paget breast cancer?

Could premerin homone replacement cause Paget breast cancer?

Unlikely: We think that combined hormone replacement including estrogen and Progesterone cause an increase in breast cancer of which paget's disease if the breast is a type. Premarin (conjugated estrogens) only contains estrogen. ...Read more

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Do the breast enhancement pills "breast actives" cause breast cancer or uterus cancer?

Do the breast enhancement pills "breast actives" cause breast cancer or uterus cancer?

Unknown: Breast enhancement pills are not regulated and therefore may have various unknown substances in them. Some of those substances, especially if they include estrogen, may increase risk of cancers. ...Read more

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Does postmenopausal hormone therapy lead to breast cancer?

Does postmenopausal hormone therapy lead to breast cancer?

Very low Risk: With due respect. The landmark study, whi, is called into question in so many ways. The nih spent millions to answer very little. As an re, i feel there are many facets to HRT and a careful and comprehensive evaluation of the literature supports a very minimal at best increase in breast cancer and the evidence points to the progestin component only (provera). Consultation warranted. ...Read more

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Is dcis breast cancer genetic?

Is dcis breast cancer genetic?

It can be: Dcis, the earliest form of breast cancer, can be associated with brca mutations. 13% of women under 50 diagnosed with dcis had a brca mutation in retrospective (looking backwards) studies. Women with a family history of breast or ovarian cancer or dcis before age 50 should have genetic counseling. For more info: http://clincancerres.Aacrjournals.Org/content/13/14/4306.Full. ...Read more

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Is there a benefit to chemotherapy in hormone receptor positive, node positive postmenopausal breast cancer?

Is there a benefit to chemotherapy in hormone receptor positive, node positive postmenopausal breast cancer?

Often: There is increasing data based on the oncotype DX test in women with 1-3 positive notes that shows that some women will not get much benefit from chemo and some will get a great deal. It can be useful in cases where a woman is reluctant to take chemo. This is done on tissue that has been already removed. Most oncologists believe that women who have multiple positive nodes should get chemotherapy. ...Read more

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My mom had lobular breast cancer at 52. Brca negative. Is lobular breast cancer more genetic based than ductal?

My mom had lobular breast cancer at 52. Brca negative. Is lobular breast cancer more genetic based than ductal?

No its medullary: a quote from Lancethttp://www.ncbi.nlm.nih.gov/pubmed/9167459: "The occurrence of invasive lobular carcinoma and invasive ductal carcinoma was not significantly different between carriers of BRCA1 or BRCA2 mutations and controls. Medullary or atypical medullary carcinoma was, however, found more often in BRCA1 (13%, p ...Read more

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Hormone therapy for menopausal symptoms cause breast cancer?

Hormone therapy for menopausal symptoms cause breast cancer?

NO BUT INCREASE RISK: Hormone therapy does not cause breast cancer but it does increase your risk of breast cancer. According to the national nurses health study using hormone replacement therapy for 10-15 yrs increases risk about 20%, if used more than 15 yrs it doubles to around 40%. Talk to your doctor to help you decide how to better manage postmenopausal symptoms. ...Read more

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Can small breast women have breast cancer detected easier?

Can small breast women have breast cancer detected easier?

Not necessarily: It may be easier to palpate a lump in a small breast because there is less tissue, however, some brest cancers are only found on mamogram. I would not use the fact that u have small breasts to forgo getting screening mamograms. ...Read more

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Is breast density a risk factor for breast cancer? Mammogram noted "extremely dense breasts".

Yes, breast density: is a risk factor for breast cancer. The relative risk for extremely dense breasts is about 4x the relative risk of patients with almost entirely fatty breasts, and about 1.6x the RR for "average" density breasts. Find out all you need to know at http://www.breastdensity.info/ ...Read more

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Can mammograms detect breast cancers?

Can mammograms detect breast cancers?

Yes most of the time: Accuracy of mammography in varies serious positive for ca any where from 78% to 90 % but over all not 100% as in biopsy. For the diagnosis other parameters are involved like specific findindings, besides age , family history, physical findings , genetic diseases , personal habits , medications etc regular breast examination , awareness is also essential for early diagnosis and cure. ...Read more

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Dr. John Yim Dr. Yim
3 doctors agreed:
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Does breast bondage causing breast cancer?

Dr. John Yim Dr. Yim
3 doctors agreed:
Does breast bondage causing breast cancer?

No.: Breast bondage does not cause breast cancer and almost certainly has no effect on raising the risk of breast cancer. ...Read more

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Can ovarian cancer and breast cancer be hereditary?

Can ovarian cancer and breast cancer be hereditary?

Yes, of course: This is one of the classic hereditary cancer syndromes. Sorry, i don't have enough characters to be allowed to give you a full asnwer here, but quoting wikipedia: http://en.Wikipedia.Org/wiki/hereditary_breast%e2%80%93ovarian_cancer_syndrome. ...Read more

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Detecting breast cancer appropriate to have thermography for women vs mammogram?

Detecting breast cancer appropriate to have thermography for women vs mammogram?

The use of: mammography as a screening test has been validated by many years of outcomes data. Thermography, not so much. ...Read more

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Does male breast cancer have different symptoms from female breast cancer?

Does male breast cancer have different symptoms from female breast cancer?

Not really: Most breast cancers are without symptoms. That is why many are missed. Males having such little breast tissue may notice a lump earlier but not always so many go undetected because few realize that men are also susceptible to breast cancer. ...Read more

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Hormone sensitive breast cancer 7 yrs ago; 3 small spots w breast cancer cells in lungs just showed; now using femara; should I stop using astaxanthin?

Astaxanthin: I will recommend stopping astaxanthin which is a carotenoid but also a potent antioxidant. How Femara (letrozole) or Letrozole interacts with this compound and because of the super radical and antioxidant effects it can potentially make Femara (letrozole) less effective is possible. There is no proven benefit of this in breast cancer. Hopefully this helps. ...Read more

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What kinds of breast cancer are fueled by hormones?

What kinds of breast cancer are fueled by hormones?

Receptor Positive: Breast cancers that have receptors for estrogen and Progesterone are fueled by hormones. These are the so called er and pr positive tumors. Hormone therapy plays and important role in the treatment of these types of breast cancers. ...Read more

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Can you tell me how is breast cancer hormone dependent?

Can you tell me how is breast cancer hormone dependent?

Through receptors.: Breast cancer cells have receptors on the surface. You can think of these like light switches. Most breast cancers have receptors for estrogen or progesterone, the female hormones. These hormones can bind to the receptor turning it on, and telling the cancer cell to grow. Often the treatment for breast cancer involves blocking these hormone or the receptors they bind to. I hope that helps! ...Read more

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Can you tell me how is breast cancer "hormone dependent"?

Can you tell me how is breast cancer "hormone dependent"?

Through receptors.: Breast cancer cells have receptors on the surface. You can think of these like light switches. Most breast cancers have receptors for estrogen or progesterone, the female hormones. These hormones can bind to the receptor turning it on, and telling the cancer cell to grow. Often the treatment for breast cancer involves blocking these hormone or the receptors they bind to. I hope that helps! ...Read more

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What are the hormones someone should take if they have breast cancer?

What are the hormones someone should take if they have breast cancer?

Hormones/Breast CA: If i understand the question correctly you are asking about safe hormones for postmenopausal women with breast cancer? None, if the cancer is er/pr positive. We prescribe estrogen blocking drugs to decrease the risk of recurrence. We discourage hormone use in all breast cancer patients. ...Read more

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Can you tell me about hormone receptive metastic breast cancer?

Stage 4: This means that the cancer has spread from the breast to other areas of the body ( bone, lung, liver, etc.)-Stage . It is a tumor that should respond to chemotherapy and hormone therapy. Hormone therapy is a blocker-it blocks the tumor cell from being able to feed off of estrogen, which causes its growth. The hormone therapy should stop the tumor from growing. ...Read more

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In what conditions mustn't I use hormone supplements? Breast cancer?

In what conditions mustn't I use hormone supplements? Breast cancer?

Yes, ER(+) breast ca: Hormone replacement therapy (hrt), which generally refers to estrogen and Progesterone replacement after a women has reached menopause, has been shown to increase the risk of breast cancer if taken in combination for more than 5 years. If you are already diagnosed with a hormone positive breast cancer, we do recommend discontinuing hrt. ...Read more

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How do lutein and zeaxanthin hormones affect breast cancer?

I hope no adversity: Lutein is present in spinach and other dark leafy vegetables and when we eat it, our body makes zeaxantin. Both of these chemicals appear to be essential for healthy macular function (reading and color). Macular degeneration was studied by the national eye institute using a vitamin combination in the lat '80s and this study is being repeated using both lutein and zeaxanthin as well as fish oil. ...Read more

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Can the hormone drugs taken after breast cancer surgery cause other cancers?

Can the hormone drugs taken after breast cancer surgery cause other cancers?

Hormonal blockade: Depending upon your age and menstrual status your oncologist will help choose a medication to block the receptors for estrogen and Progesterone or one that will block the production of those hormones. These drugs minimize the ability of these hormones to stimulate the growth of breast and breast cancer cells. Some of them are associated with a risk of endometrial cancer but it is minimal. ...Read more

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What is the relationship of her2 and p53 with hormone receptors in breast cancer?

What is the relationship of her2 and p53 with hormone receptors in breast cancer?

Complicated: Her-2 is an oncogene usually (not always) associated with er- tumors. We know that it is in general associated with a worse prognosis, but women with her 2+ tumors may respond dramatically to Herceptin (trastuzumab) - a monoclonal antibody. P53 is a tumor suppressor gene. The relationship between p53 and er is currently under study - it may be that p53 mutations may play a role in tamoxifen responsiveness. ...Read more

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How will i know breast cancer hormone therapy is working?

Depends on situation: If you are receiving hormonal therapy for metastatic breast cancer you will hopefully notice improvement in symptoms from the cancer or by seeing an improvement on another scan. If you are taking hormonal therapy to minimize the chance of recurrence, there is no way to know how well it is working for you as an individual. However, many studies prove that it decreases the chance of recurrence. ...Read more

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Dr. Liawaty Ho Dr. Ho
4 doctors agreed:
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Chemotherapy hormone receptor positive node breast cancer?

Dr. Liawaty Ho Dr. Ho
4 doctors agreed:

D/W oncologist: Treatment will depend not only the stage but also the biology of the cancer- whether it is estrogen positive, her2neu positive, whether it is lymph node positive or not. Also depends on your preference and overall health condition. Different test like oncotype dx, mammaprint can give you more info-re- recurrence risk of cancer and will be helpful in choosing the right therapy for you.D/w your md. ...Read more

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Breast cancer : how long and how much does it cost for the hormone treatment?

Breast cancer : how long and how much does it cost for the hormone treatment?

Depends on cancer: Usually five years for hormonal treatment, but every patient and every cancer is unique. Your specialists will be able to answer the question, and explain the rationale. ...Read more

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It's it okay for me to take spironolactone if I have a family history of breast cancer? I know it affects hormone levels.

It's it okay for me to take spironolactone if I have a family history of breast cancer? I know it affects hormone levels.

Unknown: Great question! spironolactone increases free estrogen levels in the blood and decreases androgen effects, and in men can cause breast growth. There are no studies that have looked at this question. My best answer is that theoretically, it may increase your risk, as estrogen plays a role in breast cancer development. But if you need spironolactone, you should probably take it. ...Read more

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,ovarion or breast cancer dies not run in my family. May i safely continue hormone replacement.

,ovarion or breast cancer dies not run in my family. May i safely continue hormone replacement.

Be careful: At your age, the risk with hormone therapy increases. You need to be careful. When treating with hormones, you want to use the smallest dose possible and treat for the shortest time possible. It is very important that you meet with your physician to discuss your risks and consider checking genetic studies, and hormone levels. Make sure you are screening for breast disease as well. Be careful! ...Read more

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Dr. Liawaty Ho Dr. Ho
2 doctors agreed:
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Breast cancer or hormone imbalance if your nipple is leaking something?

Dr. Liawaty Ho Dr. Ho
2 doctors agreed:
Breast cancer or hormone imbalance if your nipple is leaking something?

Nipple discharge: Nipple discharge could be on 1 or both breasts, could be physiological or abnormal. The color of discharge is crucial. Many factors can cause nipple discharge-eg. Stimulation, drugs, pregnancy- these usually affected both breast. Infection , tumor or cancer in the breast ducts(bloody&affected one nipple); increase prolactin hormone-another important cause . See your md to find the cause & therapy. ...Read more

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Does postmenopausal hormone therapy lead to breast cancer?

Very low Risk: With due respect. The landmark study, whi, is called into question in so many ways. The nih spent millions to answer very little. As an re, i feel there are many facets to HRT and a careful and comprehensive evaluation of the literature supports a very minimal at best increase in breast cancer and the evidence points to the progestin component only (provera). Consultation warranted. ...Read more

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Is it true that female hormone therapy can increase the risk of breast cancer?

Is it true that female hormone therapy can increase the risk of breast cancer?

Yes: Certain hormones, especially longer use of estrogens, can increase a person's risk of breast cancer. Estrogen is listed as a known carcinogen on the fda web site & there is a class action lawsuit ongoing against premarin (conjugated estrogens). See site: http://m.Cancer.Org/cancer/cancercauses/othercarcinogens/generalinformationaboutcarcinogens/known-and-probable-human-carcinogens. ...Read more

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Do hormones from the birth control increase a woman's risk of developng breast cancer?

Possibly: The birth control pills that have unopposed estrogen have been associated with an increased risk of breast cancer. Although this remains controversial. ...Read more

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Breast cancer : how long and how much exposure to the pill or hormone treatment causes it?

Breast cancer : how long and how much exposure to the pill or hormone treatment causes it?

Pill OK ERT not sur: Most studies show that birth control pills do not increase the risk of breast cancer. Prolonged usage of post-menopausal ert probably increases risk. For most women short term ( a few years) of ert to help menopausal symptoms is probably safe (unless you are at high risk), but i recommend decreasing dosage after 2-4 years and trying to get off estrogen altogether unless symptoms are intolerable. ...Read more

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Dr. Mark Hoepfner
1,067 doctors shared insights

Breast Carcinoma (Definition)

Most breast cancers are carcinomas. This is a type of breast cancer. These cancers start in the cells that line organs and tissues. In fact, breast cancers are often a type of carcinoma called adenocarcinoma, which starts in cells that make glands (glandular tissue). Breast adenocarcinomas start in the ducts (the milk ducts) or ...Read more


Dr. James Dukelow
1 doctor shared a insight

Hormone (Definition)

A hormone (from greek ὁρμή, "impetus") is a chemical released by a cell or a gland in one part of the body that sends out messages that affect cells in other parts of the organism. Only a little amount of hormone is required to alter cell metabolism. In essence, it is a chemical messenger that transports a signal from ...Read more