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Doctor insights on: Hla Dr4 Flow Cytometry

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Hematologist wants to repeat flow cytometry. Any risks?

No: It is a specialized blood test which does not have any harmful effects on the patient, other than a needle stick to draw a blood sample or a biopsy of the tissue to be tested. ...Read more

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How long does it take to receive results from a peripheral blood flow cytometry test?

How long does it take to receive results from a peripheral blood flow cytometry test?

Cytometry test: Hard to say as time various greatly with each doctor and lab. Best bet is to call the doctors office and ask. ...Read more

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The lymphoid population consists of polyclonal b cells cd19, cd20, cd45 pos, cd5, cd10 neg w/o light chain. What does this mean on flow cytometry?

This is normal: We would worry if you had Monoclonal Lymphocyte excess, a polyclonal pattern is normal.
But why did you have the Flow cytometry done in the first place? Give us more detailed history if you need our guidance. ...Read more

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What does normal cd34 number mean in flow cytometry report? What are cd numbers?

What does normal cd34 number mean in flow cytometry report? What are cd numbers?

Stem cells: Cd numbers are "cluster of differentiation" numbers. Cd34 is a cell marker for stem cells and other cells in blood. ...Read more

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The flow cytometry results show no abnormal lymphoid population. What does it mean? What is flow cytometry?

The flow cytometry results show no abnormal lymphoid population. What does it mean? What is flow cytometry?

For ab. Blood cells: Flow cytometry is routinely used in the diagnosis of health disorders, especially blood cancers, but has many other applications in basic research, clinical practice and clinical trials. A common variation is to physically sort particles based on their properties, so as to purify populations of interest. ...Read more

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Flow cytometry shows 53% cd4+30 dual and absolute count of 2, 425. Also found some cd4+25 dual 3% absolute count 137. Is this normal? Sign of disease?

Flow cytometry shows 53% cd4+30 dual and absolute count of 2, 425. Also found some cd4+25 dual 3% absolute count 137. Is this normal? Sign of disease?

What's the tests for: Since there is no single blood test which provides a diagnosis and flow cytometry is a dynamic process, what was your doctor trying to look for? What were the indications? Were the CD4 CD25 + or -? ...Read more

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Can an excisional lymph node biopsy of begnin be accurate when the node didn't have enough cells to do a flow cytometry?

Can an excisional lymph node biopsy of begnin be accurate when the node didn't have enough cells to do a flow cytometry?

Yes: If the the lymph node biopsy is adequate for evaluation in terms of sample size for the pathologist, then a benign lymph node diagnosis should be adequate even in the absence of flow cytometry data. Flow cytometry is helpful as ancillary data when working up a diagnosis of lymphoma or leukemia in conjunction with the biopsy. But if the biopsy is benign it doesn't add much. ...Read more

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Marrow aspirate flow cytometry. What's importance of the dominant markers in lymphocyte vs. Blast gates? Eg. Lymph CD2~5~7~38 Blast 22~34~45~117~hladr

Marrow aspirate flow cytometry. What's importance of the dominant markers in lymphocyte vs. Blast gates? Eg. Lymph CD2~5~7~38 Blast 22~34~45~117~hladr

Exactly400Characters: I'm not here to answer. This is beyond my expertise. But I would like to remind you, & others, that we are restricted to 400 characters (not words, but individual letters, etc).I would suspect that a question like this would require some more information before someone would want to commit to an answer and, anyways, the person who ordered and/or did the aspirate should be consulted for definitive answers. ...Read more

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Will a flow cytometry test exclude lymphomas such as hodgekins and non hodgekins, plus what other cancers will it exclude? Done at BAYLOR COLLEGE OF

Will a flow cytometry test exclude lymphomas such as hodgekins and non hodgekins, plus what other cancers will it exclude? Done at BAYLOR COLLEGE OF

Lymphomas: Flowcytometery test will exclude non-hodgkins lymphoma. However, it does not exclude hodgkins lymphoma.
Flowcytometery is done to diagnose and classify blood/bone marrow and lymph node cancers (leukemia and lymphomas). Leukemias are of many type; some of them can not be diagnosed with this test such as myeloproliferative diseases (CML, ET, polycythemia vera etc) and MDS (myelodysplastsic syndrome ...Read more

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Can a lymph node fna with flow cytometry rule out lymphoma?

Can a lymph node fna with flow cytometry rule out lymphoma?

Not 100%: Many enlarged lymph nodes are not cancerous are instead benign and a result of another disease process. An fna is a good starting test for evaluating lymph nodes that appear to not be associated with other things that go along with lymphoma, but if suspicion is high, a fine needle aspiration (fna) is not enough and an excisional biopsy is preferred. ...Read more

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Why would you do flow cytometry if EBV serology is positive and no blasts were seen in wbc?

Why would you do flow cytometry if EBV serology is positive and no blasts were seen in wbc?

Lymphoma?: Ebv has been associated with post-transplant lumphoprolifeative disorder and I believe this is your question. What the doctors are looking for is the clonality of the b lymphocytes and any rearrangements in the normal genes of your immunoglobulins or antibodies with some of the ebv genes. In many instances there will be no circulating blasts. ...Read more

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What would tcells 83% cd4/cd8 ratio of 6.5, Nk 2%, polytypic bcells 15% mean? I've been having abnormal blood work so they completed a flow cytometry.

What would tcells 83% cd4/cd8 ratio of 6.5, Nk 2%, polytypic bcells 15% mean? I've been having abnormal blood work so they completed a flow cytometry.

Not that much: Cannot say in your particular case, but generally, there's a lot of variability in these. BUT in HIV or other immunosuppression, the T cell count is low and the CD4 ratio is LOW. Below 2 not above 5. BUT the polytypia, the elevated counts all imply an ongoing chronic infection such as TB, chronic viral infection (non-HIV) syphillis, lyme, etc. ...Read more

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Can Splenic Marginal zone lymphoma be missed in PET/CT and flow cytometry in early stages?

Yes: If there is not impressive splenomegaly / enlarge lymph nodes and there are no / few lymphoma cells in the blood, it will be impossible to make the call, and probably not even possible to suspect the illness. ...Read more

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What would cd8+/cd57+ large granular lymphocytes found in peripheral blood flow cytometry mean with loss of cd7?

What would cd8+/cd57+ large granular lymphocytes found in peripheral blood flow cytometry mean with loss of cd7?

Want to read report: Hi. Usually the purpose of flow cytometry is to determine whether an elevated white cell population (e.g., lymphocytes) is monoclonal and thus indicative of leukemia. Flow cytometry uses specific antibodies against specific cell surface white cell proteins (CD's, or Classification Determinants) to assess for monoclonalitiy of cell populations. What is report conclusion? Good luck! ...Read more

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Is there any thing of concern in my flow cytometry when it states "degenerating T cells also noticed" 23% of the lymphoid population are large granular lymphocytes, an inverted cd4:cd8 ratio, and under the Blasts section it stayed that cd45 dim makes up 3

Is there any thing of concern in my flow cytometry when it states "degenerating T cells also noticed" 23% of the lymphoid population are large granular lymphocytes, an inverted cd4:cd8 ratio, and under the Blasts section it stayed that cd45 dim makes up 3

Please talk to your: Doctor, flowcytometry is a specialized complex blood test, your Doctor or the Doctor who ordered that test are the best to educate you on the results in the context of the whole clinical picture, goodluck ...Read more

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32 weeks pregnant. WBC currently at 14. Full blood work up, all results negative except flow cytometry showing. 01 for leukemia - what does this mean!

32 weeks pregnant. WBC currently at 14. Full blood work up, all results negative except flow cytometry showing. 01 for leukemia - what does this mean!

Need to see actual: Report. All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, pregnant women normally have higher WBC counts and your is in the normal range. ...Read more

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What are chances of hodgekins lympho if flow cytometry negative, good smear no abnormalities, neg ct scan of neck and abdomen, negative chest xray?

What are chances of hodgekins lympho if flow cytometry negative, good smear no abnormalities, neg ct scan of neck and abdomen, negative chest xray?

None so far: If all these tests are negative (especially the ones presumably done on your lymh node tissue) and you have no enlarged lymph nodes anywhere other than the sampled area and no symptoms.. for now, at least, you have no Hodgkin's ...Read more

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My spleen is 17.7 CM in length, Normal Bone marrow, flow cytometry, CT/PET, no Hepatic Problem, Sever fatigue, night sweat, Cancer is possible?

My spleen is 17.7 CM in length, Normal Bone marrow, flow cytometry, CT/PET, no Hepatic Problem, Sever fatigue, night sweat, Cancer is possible?

Doubtful.: With a normal CT scan, pet scan, and bone marrow, the chances of having cancer would be small. Because of your persistent symptoms, however, I would continue to follow up with your doctor until my diagnosis can be made. Maybe an infectious cause? Good luck. ...Read more

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Itchy face (especially nose), fatigue, headaches, achy joints (elbows knuckles, wrists)and left heel, nausea. Flow cytometry good mri good any ideas?

Itchy face (especially nose), fatigue, headaches, achy joints (elbows knuckles, wrists)and left heel, nausea. Flow cytometry good mri good any ideas?

Itchy face: Why flowcytometery test and MRI were performed? May be you have something more than what you mentioned such as swollen lymph nodes or mass somewhere in the body etc. Probably MRI was ordered due to headache.Need more information. ...Read more

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22 yo; chr. Lyme; reactive synovitis; + hla-b27; no nsaids/steroids! Opioids no help. Echo = dense tissue inhibited compression fem. Vein; flow norm.

22 yo; chr. Lyme; reactive synovitis; + hla-b27; no nsaids/steroids! Opioids no help. Echo = dense tissue inhibited compression fem. Vein; flow norm.

Wait: What did you say? Lyme reactive synovitis occur in untreated long term lyme. It could respond to anti inflammatories and even disease modifying agents. B 27 refers to inheritance or ankylosing spondylitis or psoriatic arthritis. Not related to lyme. The other stuff makes no sense, could you elaborate? ...Read more

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Is testing positive for HLA-B27 a good thing?

Is testing positive for HLA-B27 a good thing?

Maybe: You're more at risk for reactive arthritis and ankylosing spondylitis, and finding you have HLA-B27 may help clinch the diagnosis if it seems likely already. Why were you tested? The vast majority of folks who are positive never have any problems with it whatsoever. ...Read more

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What is the definition or description of: hla typing?

What is the definition or description of: hla typing?

HLA typing: Describes the determination of proteins on the cell surface which the immune system utilizes to assign self and not self. There are multiple genes which encode these proteins on chromosome 6. ...Read more

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What type of doctor can order a hla b27?

Rheumatologist: On an internist or family doctor can order it if indicated. ...Read more