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Doctor insights on: Hla Dqb1

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Is hla b27 testing a very common procedure?

Is hla b27 testing a very common procedure?

Yes: There are several labs which run this test. It looks for a protein on the surface of your white blood cells. ...Read more

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Positive ANA 1:160 homogeneous, positive EBV (via, igg) at 3.97 H. See rheumatologist? Possible diagnoses?

Positive ANA 1:160 homogeneous, positive EBV (via, igg) at 3.97 H. See rheumatologist? Possible diagnoses?

Symptoms?: We treat patients not lab results, you can still see a rheumatologist to sort things out for you, best wishes ...Read more

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Is hla-dq2 autosomal dominant?

Is hla-dq2 autosomal dominant?

No: The histocompatibility antigen system is totally different and has nothing to do with being either dominant or recessive. ...Read more

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Blood tests showed high antibodies to: ana, ssdna, sm, rnp/sm, ssa(ro), ssb(la), scl-70, centromere. Is this likely lupus or a different automimmune?

Prob false positive: To have all these antibodies to be positive is suggestive of a false positive result. Virus infection can cause similiar findings. Ultimately these results have to be interpretted in the context of your doctor's findings. Talk to your doctor. ...Read more

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Ana positive 160 poss mtcd w/o lupus markers. What can cause 300 mg/dL lambda 200 lambda if no paraprotein? Check igd/e? Urine spot lambda bjp found

Ana positive 160 poss mtcd  w/o lupus markers. What can cause 300 mg/dL lambda 200 lambda if no paraprotein? Check igd/e? Urine spot lambda bjp found

BJP: Bence Jones proteins, light chain, occur in multiple myeloma , lymphomas/chronic leukemias, monoclonal gammopathy of undetermined significance which can go on to myeloma at the rate of only 1%/yr -small risk),amylodosis,cryoglobunemia, Autoimmune disease can give false positive. Check IFE & bone marrow http://www.livestrong.com/article/372234-about-multiple-myeloma-and-bence-jones-protein/ ...Read more

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ENA test screened for SS-A, SS-B, RNP, Sm, Scl-70 & Jo-1. Negative result. I'm ok?

ENA test screened for SS-A, SS-B, RNP, Sm, Scl-70 & Jo-1. Negative result. I'm ok?

May be: Why were these tests done? You must have had some symptoms for your doctor to order these tests. Negative results on blood tests are not an assurance that there is no disease. Please follow your doctor's advice for follow-up care. ...Read more

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Ana positive 1:80 homogeneous pattern & 1:160 centromere pattern...Additional tests needed or just by centromere pattern crest & scleroderma r present?

Ana positive 1:80 homogeneous pattern & 1:160 centromere pattern...Additional tests needed or just by centromere pattern crest & scleroderma r present?

Almost certain: Positive anti-centromere antibodies would indicate the presence of scleroderma/crest, better if anti–scl-70 antibodies also present, plus clinical symptoms and signs. ...Read more

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ANA 1:160 homogenous, anti ssDNA 42, normal Rh factor, ESR, anti dsDNA , neg HLA B27. Tests due to severe joint pain- is this indicative of lupus??

ANA 1:160 homogenous, anti ssDNA 42, normal Rh factor, ESR, anti dsDNA , neg HLA B27. Tests due to severe joint pain- is this indicative of lupus??

Might be.: These labs do not rule lupus out nor do they rule it in. I think your doc should keep looking and monitor your progress over time. Depending upon joints could represent parvovirus although that is just a wild guess. Your clinical picture and progress is most important. ...Read more

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What autoimmune diseases are associated with a positive HLA-B57 test?

What autoimmune diseases are associated with a positive HLA-B57 test?

HLA-B57: HLA-B57 gene significance if present, people who has it have increased risk of auto-immune psoriasis, and also increased risk of hypersensitivity to abacavir, an anti HIV drug ...Read more

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Av test positive .Ra factor positive .Joint pain .Ccp antibody test negative.Raised esr.Plz diagnose my disease.

Av test positive .Ra factor positive .Joint pain .Ccp antibody test negative.Raised esr.Plz diagnose my disease.

Cannot diagnose: Although these lab values are interesting, taken out of the context of your symptoms and findings on physical examination, plus further testing there is no way in which to diagnose over the internet. See a rheumatologist and get appropriately assessed. ...Read more

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What would cause a high positive ANA (1:640) speckled, nucleolar with a low positive smooth muscle antibody (1:40) but negative SS-A, SS-B, anti-Smith, RNP, SCL-70, Anti Jo antibodies? Liver disease?

Probably normal: Many people have a positive ANA without being sick. If you also have elevated liver enzymes, a workup for autoimmune hepatitis may be continued, but if there's nothing to suggest a liver problem biochemically, I'd not be in a hurry to diagnose despite anti-smooth-muscle. ANA means nothing apart from the clinical picture. Best wishes. ...Read more

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Elevated EBV ab VCA IgG <8 and EBV nucleaer antigen ab IgG test 4.2. & anti-dna(ss)igg ab qn ( 119)& c react protien(5.6) what are implications?

Elevated EBV ab VCA IgG <8 and EBV nucleaer antigen  ab IgG test 4.2. & anti-dna(ss)igg ab qn ( 119)& c react protien(5.6)  what are implications?

Nothing.: Ebv antibodies indicate you had a previous infection, but not active. The c-reactive protein needs a units indicator - that is either normal or somewhat elevated. The anti ss dna is extremely nonspecific and very rarely indicated; I have no idea why that was ordered, discuss with your doctor. ...Read more

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The clients blood typing reveals Rh antigens what blood type would the client have Rh receptive, Rh negative , Rh resistant, Rh positive

The clients blood typing reveals Rh antigens what blood type would the client have Rh receptive, Rh negative , Rh resistant, Rh positive

Rh : Rh antigens are present in every blood. You would need to be more specific. Also, they blood type (a, b, ab, 0) is not connected/related to the rh + or rh - types; they are inherited independently. ...Read more

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I tested positive for the ANA screen, 1:160 titer, speckled pattern. Rheumatoid factor 21, SED rate 22. Does this indicate Rheumatoid arthritis?

I tested positive for the ANA screen, 1:160 titer, speckled pattern. Rheumatoid factor 21, SED rate 22. Does this indicate Rheumatoid arthritis?

No: The rheumatoid factor was barely above negative. It is usually greater than 150 in RA. The CCP antibody is a much more specific test. The diagnosis of RA depends on several diagnostic criteria. The rheumatoid factor is nonspecific. ...Read more

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Do specific hla antigens predispose someone to ischemic heart disease?

Do specific hla antigens predispose someone to ischemic heart disease?

Yes and no: There is no direct correlation between hla types and the incidence of CAD that I am aware of. However, certain hla types, ie b27, are associated with CAD thought due to chronic inflammation and vascular injury. For instance many chronic autoimmune disease patients have a higher incidence of cad. ...Read more

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What does a positive NEUTROPHIL CYTOPLASMIC AB.CLASSIC & NEUTROPHIL CYTOPLASMIC AB.PERINUCL & Antinuclear antibodies mean?

What does a positive NEUTROPHIL CYTOPLASMIC AB.CLASSIC	& NEUTROPHIL CYTOPLASMIC AB.PERINUCL & Antinuclear antibodies mean?

See details: This test must be evaluated in the context of the clinical picture. The pANCA and MPO can be positive in several different diseases. ...Read more

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Cause of a positive monoclonal T cell beta gene rearrangement?

Cause of a positive monoclonal T cell beta gene rearrangement?

Tumor: Monoclonal proliferation of lymphoid cells is usually an indication of tumor of the lymphoid tissue. ...Read more