Doctor insights on:
Hla B27 Positive Treatment
I am hla-b27 positive. I've suddenly had 6 iritis flareups in the last 2 years. I think they are caused by contact lens abuse. Thoughts please.
I am suffering with severe pain in my hips for last 5 yrs, have hla b27 positive. Mri was okay. Please advice?
AS: Ankylosing spondylitis is of concern. A plain x-ray of the sacroiliac joints would pick up images of bone sclerosis better than a mri. A rheumatologist can discern and advise. Traumatic injury to the sacroiliac joints is a consideration. Has there been participation in extreme sports? An osteopath can evaluate injury to the sacroiliac joints. ...Read moreSee 1 more doctor answer
I had a positive HLA B27, positive ANA, positive SM anitobody, and a positive RNP. And Raynauds, is this likely Lupus?
Lupus is a clinical: Diagnosis, made based on the presence of physical symptoms and specific organ involvement and is not a diagnosis made by the presence of a genotype or auto antibody. What symptoms have you had that prompted your physician to do this series of tests? What is the opinion of the rheumatologist seeing you (or are you still awaiting a visit with rheum?) These disorders are complex/overlap. Talk w/ URMD ...Read moreSee 1 more doctor answer
Swollen top of foot over a week and pain in heel after walking. No discoloration. HLA-B27 positive plus have Hasimotos. Blood clot or autoimmune cause?
I would think: Autoimmune, but get that foot checked out by a Dr. just to be sure. ...Read more
Hi. I just want you to ask about stem cell therapy. Actually before hla b27 was positive now doctor told me to do hip replacement so what I do?
Don't quite undersz: -stand the question. Pretty young for ankylosisng spondyosis 2 appear. Also, there R about 10% or so false positives. No stem cell activity in degerative hip disease. R U sure of AS?personally I suspect it the HLA-B27 is false& any hip disease is unrelated. Get in 2 C an internist who specializes in AS. Also, get a second opinion. ...Read more
Positive for hla-b27. This procedure rules out the b27:06 & 27:09 alleles which lit suggests aren't associated w/ spondyloarthropathies. What this mean?
Spondyloarthritis: Hlab27 is a generic marker that is in 8% of the caucasian population. Many people with diseased called spondyloarthropathies (ankylosing spondylitis, psoriatic arthritis, and crohns/uc related arthritis) will have a positive b27, but not all those with b27 will develop issues (in fact, the vast majority don't). The larger question is are the symptoms consistent with spondyloarthropathy. ...Read more
Had 2 blood tests for hla b27. 1st test came back positive; 2nd test (pcr) came back negative. What would be the difference between the two tests?
If blood test by PCR was negative for hla b27, does this mean i definitely don't have it? (one other blood test was positive; not sure of the type).
2 blood tests done for hla b27: one was pos. And one was neg. (pcr). What is the difference of tests & what would trigger a positive with first test?
So, one test by pcr, the other test is what?
If the two tests were different, do the test that is known to be more sensitive and get two readings of it. ...Read more
No: Unless there was a lab error.Get a more detailed answer ›
My doctor told me that I am suffering from seronegative spondyloarthropathy. My crp is high 27. My hla-b27 report is also positive.
If both parents are HLA-B27+ would that guarantee all offspring to have the gene? If so would only 1 positive parent make it a 50% chance?
No: Mendel's laws. Each parent has one copy of this and one copy of another. Let us assume neither parent has two copies. There is a 75% chance. Now, why do you ask? HLA-B27 is common, and the only thing that makes it troublesome is that it gives a few percent of folks joint problems. It is not a reason to forego parenthood. Ask whether your sacroileitis might benefit from today's new Rx's. ...Read more