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Doctor insights on: Hla B27 Antigen

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Hello, could i still have rheumathoid or other type of arthritis if ana, anticcp, crp, esr, rheumathoid factor, hla-b27 antigen are all in range?

Hello, could i still have rheumathoid or other type of arthritis if ana, anticcp, crp, esr, rheumathoid factor, hla-b27 antigen are all in range?

Sounds like: You had a fairly complete serologic work-up. With this information one would expect garden variety osteoarthritis as the cause of your joint issues -- more degenerative than inflammatory. ...Read more

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Dr. Ira Katz
59 doctors shared insights

Hla B27 (Definition)

Hla = human leukocyte antigen. Important in recognition of self and not self. Different proteins (antigens) for different people. B is one of the loci, and hlab27 has been associated with predisposition to immunologic rheumatologic ...Read more


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Faitgue w/knee and hip pain, a +ccp antibody, a - hla-b27 antigen? Possible ra?

Faitgue w/knee and hip pain, a +ccp antibody, a - hla-b27 antigen? Possible ra?

Maybe: Ra is possible although the pattern of involvement is not that typical. How positive was the ccp? Unless it is strongly positive it is not that specific for ra. ...Read more

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Negative hla-b27 antigen.Normal cpk, esr.Crp 1.6. Ra neg. For 7 months stiff sore muscles in hips, shoulders back what could this be? Doctor not sure.

Negative hla-b27 antigen.Normal cpk, esr.Crp 1.6. Ra neg. For 7 months stiff sore muscles in hips, shoulders back what could this be? Doctor not sure.

Age, side effects,,,: This could be from just age effects on your muscles, especially if you've used them a lot during your lifetime for housework or in your work. You're on two medications for muscle relaxation that could have side effects invoking your nervous system and ultimately your muscles, and they might ache afterwards. You therefore might think of seeing your doctor to get off the meds (except nsaids). ...Read more

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Hello, could i still have rheumathoid or other type of arthritis if ana, anticcp, crp, esr, rheumathoid factor, hla-b27 antigen are all in range?

Sounds like: You had a fairly complete serologic work-up. With this information one would expect garden variety osteoarthritis as the cause of your joint issues -- more degenerative than inflammatory. ...Read more

See 1 more doctor answer
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Faitgue w/knee and hip pain, a +ccp antibody, a - hla-b27 antigen? Possible ra?

Maybe: Ra is possible although the pattern of involvement is not that typical. How positive was the ccp? Unless it is strongly positive it is not that specific for ra. ...Read more

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Fatigue, hip&knee pain with+ccp antibody and -hla-b27 antigen, could it be possible ra?

Fatigue, hip&knee pain with+ccp antibody and -hla-b27 antigen, could it be possible ra?

Probable: Ra is a clinical diagnosis confirmed by lab results and not the other way around. Hla-b27 is not a feature of RA although ccp ab is. ...Read more

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Negative hla-b27 antigen.Normal cpk, esr.Crp 1.6. Ra neg. For 7 months stiff sore muscles in hips, shoulders back what could this be? Doctor not sure.

Age, side effects,,,: This could be from just age effects on your muscles, especially if you've used them a lot during your lifetime for housework or in your work. You're on two medications for muscle relaxation that could have side effects invoking your nervous system and ultimately your muscles, and they might ache afterwards. You therefore might think of seeing your doctor to get off the meds (except nsaids). ...Read more

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What is the definition or description of: hla b27?

What is the definition or description of: hla b27?

Tissue type at B: Hla = human leukocyte antigen. Important in recognition of self and not self. Different proteins (antigens) for different people. B is one of the loci, and hlab27 has been associated with predisposition to immunologic rheumatologic diseases, especially ankylosing spondylitis. ...Read more

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Positive for hla-b27.This procedure rules out the b27:06 & 27:09 alleles which lit suggests arent associated w/ spondyloarthropathies.What this mean?

Positive for hla-b27.This procedure rules out the b27:06 & 27:09 alleles which lit suggests arent associated w/ spondyloarthropathies.What this mean?

Spondyloarthritis: Hlab27 is a generic marker that is in 8% of the caucasian population. Many people with diseased called spondyloarthropathies (ankylosing spondylitis, psoriatic arthritis, and crohns/uc related arthritis) will have a positive b27, but not all those with b27 will develop issues (in fact, the vast majority don't). The larger question is are the symptoms consistent with spondyloarthropathy. ...Read more

Antigen (Definition)

Antigens are chemicals which upon exposure to the surface or inside of the body, will cause a reaction term allergic. Many substances will do this and allergic response is the basis for immunological protection for ...Read more