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Doctor insights on: Hla B27 Antigen

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I'm hebs ag negative with a high anti hbs antibody from vaccination. This week's test was reported as hebs ag detected with anti hbs antibody of 513 miu/ml. Lft normal....Scared....Lab error?

I'm hebs ag negative with a high anti hbs antibody from vaccination.  This week's test was reported as hebs ag detected with anti hbs antibody of 513 miu/ml. Lft normal....Scared....Lab error?

Yes: That sounds like lab error. Your hbsab would provide immunity; i'm assuming yoru hbcab (core) is negative; i wouldn't worry, talk to your doctor about a retest if you are concerned, but even if you were infected, there is no reason for treatment at this time. ...Read more

Dr. Dariush Saghafi
59 doctors shared insights

Hla B27 (Definition)

Hla = human leukocyte antigen. Important in recognition of self and not self. Different proteins (antigens) for different people. B is one of the loci, and hlab27 has been associated with predisposition to immunologic rheumatologic ...Read more


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Hello, could i still have rheumathoid or other type of arthritis if ana, anticcp, crp, esr, rheumathoid factor, hla-b27 antigen are all in range?

Hello, could i still have rheumathoid or other type of arthritis if ana, anticcp, crp, esr, rheumathoid factor, hla-b27 antigen are all in range?

Sounds like: You had a fairly complete serologic work-up. With this information one would expect garden variety osteoarthritis as the cause of your joint issues -- more degenerative than inflammatory. ...Read more

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For 58+ F, Hb 10.8, RBC 3.66, PCV 34, MCV 94, MCHC 31, WBC 5.4, Pt 1.8, Iron 57, TIBC 255, TSI 22, RC 1.2, Ferritin 83 indicate which type of anemia ?

For 58+ F, Hb 10.8, RBC 3.66, PCV 34, MCV 94, MCHC 31, WBC 5.4, Pt 1.8, Iron 57, TIBC 255, TSI 22, RC 1.2, Ferritin 83 indicate which type of anemia ?

Mild anemia: Assuming you've had no recent bleeding episodes, these findings could be seen in mild/early anemia of chronic disease. Hgb and Hct are only boarder line low, and iron panel appears within the reference range. Even something as simple as a particularly heavy period could cause mild anemia of this type, though. If you have a chronic medical illness, it could cause this type of anemia. ...Read more

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+ Antimitochondrial M2 antibodies w/ 4previous elevated ALP's. Most recent ALP normal. Still suggestive for PBC?

+ Antimitochondrial  M2 antibodies w/ 4previous elevated ALP's. Most recent ALP normal. Still suggestive for PBC?

No: The diagnosis of PBC is made through liver biopsy. The other best tool is the biliruben. Taken together they give a diagnosis and prognosis for survival. As you know PBC is though to be an auto immune disease. ...Read more

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05/05/2016 Siemens Advia Centaur hep C antibody result positive.08/10/2016 Abbott Architect (cmia) hep C antibody result negative.Who is telling truth?

05/05/2016 Siemens Advia Centaur hep C antibody result positive.08/10/2016 Abbott Architect (cmia) hep C antibody result negative.Who is telling truth?

It's not really: a question of truth telling. No test is perfect: the proteins and reactants used in each test will respond to an individual's blood/biologic material, potentially, in a different way. Falsely positive or falsely negative results are not very unusual. You need to decide on a confirmatory strategy with your doctor. Retesting is necessary and an expert can help you weigh the evidence to decide result ...Read more

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HC worker. 1992 Hep B vac, 2004 titer & booster. 2012 labs hep B neg. Labs done last wk; now told that Hep B test is positive?? How can this be?

HC worker. 1992 Hep B vac, 2004 titer & booster. 2012 labs hep B neg. Labs done last wk; now told that Hep B test is positive?? How can this be?

The vaccine worked: Lab tests aren't perfect and sometimes can be wrong. Or maybe the negative result was from the wrong kind of test. Vaccination makes hepatitis B surface antibody (HBsAb) positive. Tests for surface antigen (HBsAg) or core antibody (HBcAb) remain negative. Most important, you can be sure you are immune and protected by the vaccine -- so no worries. ...Read more

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My blood test results: total bilirubin: 1.41 h ast: 40 h alt: 100 h total alk phosphatase: 43 l serum total protein: 7.1 e.R. Said hepatitis?

My blood test results:
total bilirubin: 1.41 h
ast: 40 h
alt: 100 h
total alk phosphatase: 43 l
serum total protein: 7.1

e.R. Said hepatitis?

Let's try this...: I have only a little bit of the story you've shared. Perhaps it's time to see whether the ast and alt get back to normal after two weeks off alcohol and any not-totally-necessary meds you may be taking. If so, this is the start of a healthier life after alcohol. If not, the workup for virus infections, iron overload, wilson's, autoimmunity & need for exercise can begin. Good luck. ...Read more

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I'm a hept b carrier. Recent blood test shows hbe ag reactive. What does it mean?

I'm a hept b carrier. 
Recent blood test shows hbe ag reactive. 
What does it mean?

You are infecitous: Having the "e" antigen on board in your blood is a marker that your blood is especially dangerous to others. This is true of some other body fluids as well. Make your decisions accordingly, be responsible, take medicines if your physician suggests it, and perhaps someday we will have a way to cure this. ...Read more

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Results: Hep C quant. : 2,802,680 HCV log10: 6.448. Reflex to genotype was unable to determine genotype even though there was sufficient HCV RNA?

Results: Hep C quant. : 2,802,680 
HCV log10: 6.448. Reflex to genotype was unable to determine genotype even though there was sufficient HCV RNA?

Hepatitis C virus: Sometimes it's not possible to determine the genotype of this virus, which thus makes the expected response to treatment more uncertain. This is a 'slippery virus' -there are 11 major genotypes (designated 1-11), and many subtypes (a, b, c, etc.) A hepatologist (GI subspecialist) or an ID doctor who works with Hep C patients can help you. You'll need an established relationship for treatment... ...Read more

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IDA? RBC 4.880 HGB 13.70 HCT 45.0 MCV 92.20 MCH 28.10 MCHC 30.40 RDW 14.50 PLT 368 Serum Iron, 178 Ferritin, 10.6 TIBC, 470 UIBC 292 Saturation 38%

IDA? 
RBC 4.880
HGB 13.70
HCT 45.0
MCV 92.20
MCH 28.10
MCHC 30.40
RDW 14.50
PLT 368
Serum Iron, 178
Ferritin, 10.6
TIBC, 470
UIBC  292
Saturation 38%

This looks good: I'm not sure what your question is here, but overall this information regarding your blood counts looks good. You don't look anemic, the platelets that clot your blood are in good levels, and your infection fighting WBC's are at a good level. Have a great evening! ...Read more

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I am 23 bilatral mild kne tendernes 1 year.Rib , hip , tendernes on and of.Uric acid 6.4:hct62.5% RA , anti ccp negativ.Wbc 9000 one kidney gone .P.U.V?

I am 23 bilatral mild kne tendernes 1 year.Rib , hip , tendernes on and of.Uric acid 6.4:hct62.5% RA , anti ccp negativ.Wbc 9000 one kidney gone .P.U.V?

Hematologist needed!: If you are a non-smoker, the hct of 62.5% strongly indicates a "myeloproliferative" disorder of which polycythemia vera is a variant and can give bone pain, especially if there is a high viscosity that limits blood flow and tissue oxygen delivery. The uric acid is not significantly elevated and not playing a role in your symptoms, but ongoing monitoring is required with blood disorders. ...Read more

Antigen (Definition)

Antigens are chemicals which upon exposure to the surface or inside of the body, will cause a reaction term allergic. Many substances will do this and allergic response is the basis for immunological protection for ...Read more