Doctor insights on:
Hivid Nucleoside Reverse Transcriptase Inhibitor
Azd 6244- mek inhibitor- a selective mitogen-activated protein kinase (mek) inhibitor. Mk 2206- akt inhibitor. Why prescription for me? It ? Nsclc/mets
Molecular targeting: These agents are designed to selectively knock out key pathways your tumor may use to grow. Presumably you already had your tumor tested for these different mutations. Ask the doctor offering these options to explain their rationale. These are investigational studies and many of the treatment costs may be covered-ask. ...Read more
Yes: The HIV mutates frequently, and when a mutation produces resistance to protease inhibitors this will allow that form of the virus to multiply over other forms which are sensitive. That is one of the reasons for a drug combination which makes single mutational changes less likely to be favorable to the virus. ...Read more
ACE-I: read this: http://circ.ahajournals.org/content/108/3/e16.fullGet a more detailed answer ›
Biochemistry enzymes: One induces and other inhibits action of enzyme. Great Wikipedia question. If you have never heard of it always go there first before coming here. ...Read more
Elevated EBV ab VCA IgG <8 and EBV nucleaer antigen ab IgG test 4.2. & anti-dna(ss)igg ab qn ( 119)& c react protien(5.6) what are implications?
Nothing.: Ebv antibodies indicate you had a previous infection, but not active. The c-reactive protein needs a units indicator - that is either normal or somewhat elevated. The anti ss dna is extremely nonspecific and very rarely indicated; I have no idea why that was ordered, discuss with your doctor. ...Read more
Why are viruses that code for their own kinase enzymes easier to target with nucleoside analogue drugs?
Diagnoged with cutaneous tcell lymphoma nhl.Treated with eletron beam.Interferon, gemcitabine, anthracycline, etoposide, procarbazine.Nodules over body .?
Could taking certain medication (Albuterol, Flovent, Buspar) effect Syphilis Serology test results?
Highly unlikely: The initial tests for syphilis are screening tests which are quite sensitive but may be non-specific. If these are negative it is not going to be from medications you are taking. If positive they are almost always followed up with more specific testing to be sure that they were not biologically false-positive results. ...Read more
Usually well-tolerated.: Heptovir is the generic name for lamivudine, a hepatitis B drug. For the most part, it is usually well-tolerated. Anyone could have side effects from the medications, however. Contact your doctor immediately if you have severe muscle pain or cramping, a sign of an allergic reaction, or severe abdominal pain. Good luck. ...Read more
If avodart & flomax are cy3a4 substrates & sprycel (dasatinib) is an inhibitor, why do interaction checkers show a prob. With sprycel (dasatinib) & avodart but not w/flomax?
Good Question: Avodart (dutasteride) is extensively metabolized in humans by the cyp3a4 and cyp3a5 isoenzymes. Flomax (tamsulosin) is extensively metabolized, mainly by cyp3a4 and cyp2d6 isoenzymes. Sprycel (dasatinib) is also extensively metabolized by the cyp3a4 isoenzyme but is also a weak time-dependent inhibitor of cyp3a4 and may therefore potentially increase the concentrations of Avodart and flomax. ...Read more