Doctor insights on:
Hivid Nucleoside Reverse Transcriptase Inhibitor
If u get a steroid tendon inj & r taking a cyp450 3a4 inhibitor at the same time is it like getting 3 steroid injections?
No: It is still one steroid injection. Biotransformation in liver is important for drugs given trough mouth, im and IV since those effect depend on concentration of drug in blood. Liver (and p450 enzyme system) has relatively little effect on drugs injected in joints, epidural space, tendons, body cavities. ...Read more
Not enough amounts: Quantity and concentration related, and you get nasty foul smelling greasy stools. ...Read more
Maybe but for what?: All medications, prescription & otc, as well as all dietary supplements, have potential side effects. There is no free lunch, no side effect free pill, whether medication or supplement. Aromatase inhibitors are approved for use in breast cancer in which case the potential risk of liver damage, hypertension, etc probably outweighs risk of recurrent breast cancer. So talk to your doc re what's right. ...Read more
Severe Interaction: This combination phosphodiesterase inhibitor (pde5) + nitrate has been shown to cause a drastic drop in blood pressure ( hypotension) a medical emergence that can result to death. Really deaths have been reported with this combination. Pde5 (some drugs in this class include viagra, (sildenafil) cialis, levitra). ...Read more
TCA/SSRI: Both are, depending on what they are prescribed for. The difference is in tolerability & side-effects. ...Read more