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Doctor insights on: Hivid Nucleoside Reverse Transcriptase Inhibitor

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How can reverse transcriptase inhibitors work?

Reverse transcriptas: Great wikipedia question. Need much more room than we have here. But basically they inhibit reverse transcriptase by binding to an active site on RT. ...Read more

Dr. Stephen Scholand
3 doctors shared insights

Zalcitabine (Definition)

Zalcitabine is a nucleoside reverse transcriptase inhibitor which is a kind of drug used for HIV (anti-viral ...Read more


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Advice please patient is to recieve .750mcg of hivid every 8 hours, on hand I have hivid 0.375?

Advice please patient is to recieve .750mcg of hivid every 8 hours, on hand I have hivid 0.375?

Hivid: (Zalcitabine / dideoxycytidine) was an antiretroviral medication used for HIV infection. It's sale/ distribution ended in 2006. How many years old is this medication? Don't recommend use of expired medication. ...Read more

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If u get a steroid tendon inj & r taking a cyp450 3a4 inhibitor at the same time is it like getting 3 steroid injections?

If u get a steroid tendon inj & r taking a cyp450 3a4 inhibitor at the same time is it like getting 3 steroid injections?

No: It is still one steroid injection. Biotransformation in liver is important for drugs given trough mouth, im and IV since those effect depend on concentration of drug in blood. Liver (and p450 enzyme system) has relatively little effect on drugs injected in joints, epidural space, tendons, body cavities. ...Read more

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Can you tell me what the ACE inhibitor is?

Can you tell me what the ACE inhibitor is?

Type of BP med: An ace inhibitor, or angiotensin-converting enzyme inhibitor, is a type of blood pressure medication to control high blood pressure. ...Read more

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Why do lipase inhibitors not stop 100% of the fat?

Why do lipase inhibitors not stop 100% of the fat?

Not enough amounts: Quantity and concentration related, and you get nasty foul smelling greasy stools. ...Read more

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Are 'aromatase inhibitors' healthy to take regularly?

Are 'aromatase inhibitors' healthy to take regularly?

Maybe but for what?: All medications, prescription & otc, as well as all dietary supplements, have potential side effects. There is no free lunch, no side effect free pill, whether medication or supplement. Aromatase inhibitors are approved for use in breast cancer in which case the potential risk of liver damage, hypertension, etc probably outweighs risk of recurrent breast cancer. So talk to your doc re what's right. ...Read more

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Is the selective norepinephine reuptake inhibitor, reboxetine, effective ?

Is the selective norepinephine reuptake inhibitor, reboxetine, effective ?

Evidence says not: One meta-analysis* (a study pooling results from multiple other studies) suggested that reboxetine is ineffective & may be harmful. *(eyding d et.Al. "reboxetine for acute treatment of major depression: systematic review &meta-analysis of published &unpublished placebo &selective serotonin reuptake inhibitor controlled trials."bmj. 2010; 341:c4737). ...Read more

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Any over-the-counter aromatase inhibitors?

No: There are no over the counter aromatase inhibitors. They are only available by prescription. ...Read more

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Why pde5 inhibitor cannot taken with nitrate? Thanks

Why pde5 inhibitor cannot taken with nitrate? Thanks

Severe Interaction: This combination phosphodiesterase inhibitor (pde5) + nitrate has been shown to cause a drastic drop in blood pressure ( hypotension) a medical emergence that can result to death. Really deaths have been reported with this combination. Pde5 (some drugs in this class include viagra, (sildenafil) cialis, levitra). ...Read more

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When should someone take selective serotonin re-uptake inhibitors?

Depression: These medications are usually a first line medication for depression although they have other uses. ...Read more

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Which is more effective? Tricyclics or SSRIs (selective serotonin reuptake inhibitors)?

Which is more effective? Tricyclics or SSRIs (selective serotonin reuptake inhibitors)?

TCA/SSRI: Both are, depending on what they are prescribed for. The difference is in tolerability & side-effects. ...Read more

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What is an inhibitor for the cyp2c8 (mainly involved in actos (pioglitazone) metabolism)?

What is an inhibitor for the cyp2c8 (mainly involved in actos (pioglitazone) metabolism)?

Liver enzyme: The cyp2c8 enzyme contributes to the metabolism of many drugs. This enzyme consists of less than 10% of the total cytochrome components in the liver, though has also been found in other organs. Even if inhibited, other pathways are available to metabolize drugs which helps the body avoid toxic build- up of drug metabolites. ...Read more

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What are protein pump inhibitors?

What are protein pump inhibitors?

Acid reducers: These inhibit the stomach pumps that produce acid and reduce the acid. Commonly used as treatment for acid reflux and stomach problems. ...Read more

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Why do ACE inhibitors cause hyperkalemia?

Why do ACE inhibitors cause hyperkalemia?

Block aldosterone: The primary mechanism of action of a ace inhibitors is to interrupt the renin angiotensin system. One of the results is reduced aldosterone synthesis. Aldosterone is an important hormone responsible for regulating potassium excretion by the kidney. Thus blocking aldosterone reduces the capacity of the kidney to excrete potassium. ...Read more

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Which are better ACE inhibitors or arb's?

They are equal: Both are effective and safe, some people get a dry cough on the ace inhibitors, but otherwise, they are well tolerated. ...Read more

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How do ACE inhibitors reverse microalbuminuria?

How do ACE inhibitors reverse microalbuminuria?

Unclear: I don't believe that the mechanism is well understood but they do act on the renal glomerulus, improving membrane integrity, reducing protein leakage, and thus do help microalbumenuria. In addition, they also lower blood pressure which is also beneficial. ...Read more

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How does a protease inhibitor work to treat hiv?

How does a protease inhibitor work to treat hiv?

Enzyme inhibitor: Protease is an enzyme used by the virus in its multiplication sequences of events. Inhibition of this protease makes it more difficult for the virus to multiply in the infected cell. ...Read more

Dr. Heidi Fowler
1 doctor shared a insight

Hivid (Definition)

Hivid is a nucleoside reverse transcriptase inhibitor which is a kind of drug used for HIV (anti-viral ...Read more