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Doctor insights on: Hiv Rna Test Accuracy

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Dr. Jeffrey Wint
16 doctors shared insights

Hiv (Definition)

Hiv infection is caused by a retrovirus....This retrovirus binds to CD4 cells (for the most part). You may detect the virus by several different methods. An elisa test (enzyme linked immunosorbent assay). You may also detect it by doing a test referred to as a western blot (a gel protein electrophoresis). Thirdly by pcr (polymerase chain reaction) which ...Read more


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Is my 8 wks 2 day PCR RNA + 4th Gen test negative conclusive for HIV infection after vaginal exp? Or do i need to test after 12 wks or it has to be after 13 wks? Pls answer, Thanks for any response

Is my 8 wks 2 day PCR RNA + 4th Gen test negative conclusive for HIV infection after vaginal exp? Or do i need to test after 12 wks or it has to be after 13 wks? Pls answer, Thanks for any response

Relax, Mike: I understand that you're a man worried about HIV after an unprotected episode of intercourse with a woman. The nucleic acid tests are almost always positive by this time -- we can't even estimate the frequency of their turning positive only at 12 weeks because history isn't always accurate. Retest only if you or someone close to you is obsessed over it. Love wisely and well from now on. Cheers. ...Read more

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What is the window period for p42 antigen/ antibody dual 4th gen HIV test? And the window period for HIV RNA PCR test? When can it be conclusive?

What is the window period for p42 antigen/ antibody dual 4th gen HIV test? And the window period for HIV RNA PCR test? When can it be conclusive?

See below: Please consult this site for a detailed answer. Nucleic acid tests are conclusive about a month after acquiring infection. http://www.sfaf.org/hiv-info/testing/hiv-test-window-periods.html ...Read more

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What is the accuracy of the RNA HIV test?

What is the accuracy of the RNA HIV test?

Not for diagnosis: It's very useful for monitoring the response to hiv, and it's accurate to diagnose or rule out acute HIV infection in someone with symptoms, but for simply diagnosing HIV infection, the HIV serology (antibody test) is better. That's because people who aren't infected can have false positive RNA tests, and people who are positive can have false negative RNA test. ...Read more

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What is the accuracy of the FDA approved RNA test for HIV at 18 days POST PEP?

Uncertain...: There has been little or no research on the extent to which PEP, if unsuccessful in preventing HIV, delays diagnostic test conversion. Probably a negative RNA test 18 days after completing PEP is close to 100% reliable, but nobody knows for sure. Some experts continue testing for 3-6 months after PEP. That's one of its disadvantages: prolongation of the period of uncertainty and anxiety. ...Read more

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What is the accuracy of HIV testing (antibody and antigen) 6 weeks post PEP? I had all tests (Neg) including the pcr rna test at 22 days post pep.

What is the accuracy of HIV testing (antibody and antigen) 6 weeks post PEP? I had all tests (Neg) including the pcr rna test at 22 days post pep.

HIV testing & RNA: Read the CDC updated recommendations on HIV testing. The rationale for this test being available is that HIV RNA is detectable in plasma before antibodies. A safe approach is to be tested after the eclipse period after potential exposure when no RNA nor antibodies to HIV can be detected. The RNA test is effective around 10 days after infection but seroconversion to antibodies may take 3 months. ...Read more

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Prednisone for 2 weeks can affect hiv rna pcr test and antibody test? So please tell which test to do for accuracy? Recently diagnosed with Bell's palsy

Prednisone for 2 weeks can affect hiv rna pcr test and antibody test? So please tell which test to do for accuracy? Recently diagnosed with Bell's palsy

No: Prednisone is the average dose will not affect any of the tests. Potentially massive doses (over 60 mg) taken for many months may marginally affect the tests but the difference will likely be unimportant. ...Read more

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When is a hiv rna test conclusive?

When is a hiv rna test conclusive?

Timing of test: HIV RNA test at 3 months or more after exposure is conclusive. Test may turn positive sooner, but for a negative result to be conclusive it needs to be about 3 months or more after exposure. ...Read more

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Is an HIV RNA test after 12 days accurate?

Is an HIV RNA test after 12 days accurate?

About 95%: RNA testing for HIV isn't usually recommended excapt in very high risk situations, like unprotected sex with a known-infected partner. But a negative result at 12 days probably is around 95% conclusive. For 100%, also have an HIV antibody blood test at 4 weeks. The combination of those two negative results will be conclusive. In the meantime, you can be very confident you weren't infected. ...Read more

Dr. Ed Friedlander
1,417 doctors shared insights

Human Immunodeficiency Virus (Definition)

Human immunodeficiency virus (HIV) is a lentivirus (a member of the retrovirus family) that causes acquired immunodeficiency syndrome (aids), [1][2] a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections ...Read more


Rna (Definition)

This is a building block for dna. Rna is what makes up the double helix and ...Read more