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Doctor insights on: Hiv Pcr Test Accuracy

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I had unprotected oral sex on me I saw no blood I have no sores I am circumsized I have tooken a HIV dna pcr test at 18 days and a 46 also a 4 week and 6 week duo test and a 8 week rapid test am I ok?

I had unprotected oral sex  on me I saw no blood I have no sores I am circumsized I have tooken a HIV dna pcr test at 18 days and a 46 also a 4 week and 6 week duo test and a 8 week rapid test am I ok?

You're OK: Oral sex is safe sex for HIV, with no proved transmissions by fellatio from mouth to penis, only rare ones penis to oral. You didn't need testing on account of this event and for sure not the multiple expensive ones you had. But the results from that combination of tests are conclusive. For sure you didn't catch HIV during that exposure and no further testing is needed. Best wishes and stay safe! ...Read more

Polymerase Chain Reaction (Definition)

Polymerase chain reaction is a method of finding a specific piece of dna and copying it over and over again until there is enough to study. The technique allows a scientist to detect very small amounts of dna in a swab sample then reproduce enough of it to study it. It is very sensisitive for detecting the presence of certain bacteria and is also used in doing other ...Read more


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What is the window period for p42 antigen/ antibody dual 4th gen HIV test? And the window period for HIV RNA PCR test? When can it be conclusive?

What is the window period for p42 antigen/ antibody dual 4th gen HIV test? And the window period for HIV RNA PCR test? When can it be conclusive?

See below: Please consult this site for a detailed answer. Nucleic acid tests are conclusive about a month after acquiring infection. http://www.sfaf.org/hiv-info/testing/hiv-test-window-periods.html ...Read more

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Does hcv coinfection expand only window period for antibody tests of hiv? Or does it have any affection to window period or accuracy of hiv pcr test?

Does hcv coinfection expand only window period for antibody tests of hiv? Or does it have any affection to  window period or accuracy of hiv pcr test?

Worse outcome: Coinfection with Hep C and HIV is worse than either infection alone. Window period is a minor issue compared to severity of disease. Window period can be addressed by nucleic acid tests rather than relying in antibodies. ...Read more

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Prednisone for 2 weeks can affect hiv rna pcr test and antibody test? So please tell which test to do for accuracy? Recently diagnosed with Bell's palsy

Prednisone for 2 weeks can affect hiv rna pcr test and antibody test? So please tell which test to do for accuracy? Recently diagnosed with Bell's palsy

No: Prednisone is the average dose will not affect any of the tests. Potentially massive doses (over 60 mg) taken for many months may marginally affect the tests but the difference will likely be unimportant. ...Read more

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Is there any possibility to have pcr(-) test results but still have hiv?

Is there any possibility to have pcr(-) test results but still have hiv?

Maybe: There may be a brief period between initial infection and producing enough virus to be detectable by pcr. ...Read more

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How accurate can be the results of an HIV PCR test if it was taken 10 and 20 hours after possible exposure?

How accurate can be the results of an HIV PCR test if it was taken 10 and 20 hours after possible exposure?

Too soon to test: At 10 hours after exposure, if would have been much better to take post-exposure prophylaxis rather than testing. You should still consult a doctor if you may benefit from post-exposure prophylaxis, the sooner the better. HIV PCR test, if negative at 12 weeks after exposure, would rule out HIV infection. ...Read more

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Were can I get HIV RNA PCR test?

Were can I get HIV RNA PCR test?

Almost anywhere: Any doctor can order this, but if there is an std or HIV clinic near you that is a good place to go. Some commercial laboratories may do this without a doctor's order. Call and ask. Good luck and hope this is negative. ...Read more

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Is the HIV DNA PCR test accurate enough for early diagnosis?

Yes: The PCR is highly accurate and sensitive. It may take 6 weeks to 6 months for the elisa and western blot antibody tests to be positive. Since the PCR tests for the virus itself, it is detectable earlier, before an immune response has been initiated, but at a much higher price. ...Read more

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Is an Hiv Pcr test result reliable if taken 10 days and 20 hours (almost 11)after the exposure?? Thank you

Very good, not 100%: Around 95% of newly infected people have positive PCR tests by 10-11 days. So your result is very reassuring, but for conclusive testing also have an antibody test (or duo test, i.e. antibody + p24 antigen) at 4 weeks. In the meantime, you can relax, especially if your exposure was not particularly high risk, e.g. unprotected anal sex with an infected or high risk male partner. ...Read more

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Does an HIV dna/pcr test become more or less sensitive and conclusive after the 1 month mark? After 3 or 5 months?

No: Not sure of your question, but the test is sensitive and specific each time it is performed, at the same level when testing for the hiv. ...Read more

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Hiv has many types and subtypes.so can an HIV DNA PCR test after 21 days of possible exposure rule out HIV completely?

Hiv has many types and subtypes.so can an HIV DNA PCR test after 21 days of possible exposure rule out HIV completely?

HIV testing: Certainly possible exposure to HIV is worrisome. Rest assured however that HIV testing is extremely good. The standard PCR test is used when a patient might be in the "window period"- that is between the time from infection until an antibody response is registered by the body. Your doc ordered the right test & u can breathe a sigh of relief. Please be careful next time tho-- this & other STDs suck ...Read more

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Hi. Just wanted to know how accurate is a HIV DNA PCR test at 6 and 21 days after exposure. Both tests came back as not detected.?

Hi. Just wanted to know how accurate is a HIV DNA PCR test at 6 and 21 days after exposure. Both tests came back as not detected.?

Negative: The overwhelming probability is that you are negative. This is a very accurate test and rapidly becomes positive in infected individuals. The test actually measures rna. This virus is call a retrovirus because in the cell it is converted to dna and then intercalated into the cell genome. ...Read more

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Is a four week negative HIV antibody test / negative PCR test reliable?

Is a four week negative HIV antibody test / negative PCR test reliable?

HIV diagnosis: Antibody titers have been reported to be delayed as long as six months, but this is very unusual. A negative pcr for viral RNA is virtually determinative of the absence of infection. ...Read more

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Is HIV DNA PCR test effective at three weeks of exposure while under pep ?

Is HIV DNA PCR test effective at three weeks of exposure while under pep ?

Asked and Answered: I believe this has been answered. Hiv pcr testing while on pep is not in any way appropriate to diagnose HIV infection. Once pep is stopped then HIV pcr testing is absolutely accurate three weeks after stopping the treatment. ...Read more

Dr. Sheila Smith
16 doctors shared insights

Hiv (Definition)

Hiv infection is caused by a retrovirus....This retrovirus binds to CD4 cells (for the most part). You may detect the virus by several different methods. An elisa test (enzyme linked immunosorbent assay). You may also detect it by doing a test referred to as a western blot (a gel protein electrophoresis). Thirdly by pcr (polymerase chain reaction) which ...Read more


Dr. Ed Friedlander
1,461 doctors shared insights

Human Immunodeficiency Virus (Definition)

Human immunodeficiency virus (HIV) is a lentivirus (a member of the retrovirus family) that causes acquired immunodeficiency syndrome (aids), [1][2] a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections ...Read more