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Doctor insights on: Hiv Ag Ab

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Hi can HIV stay Dormant for 30 months and not be detected on HIV ag/ab combo testing?

Hi can HIV stay Dormant for 30 months and not be detected on HIV ag/ab combo testing?

In Theory: I suppose anything is possible but it is highly unlikely for someone with HIV to not react positive for 30 months - assuming the person is being tested regularly (every 6 months or so). HIV generally will show up on the ag/ab test within 6 months of it being contracted. ...Read more

Dr. Michael Kleerekoper
16 Doctors shared insights

Hiv (Definition)

Hiv infection is caused by a retrovirus....This retrovirus binds to CD4 cells (for the most part). You may detect the virus by several different methods. An elisa test (enzyme linked immunosorbent assay). You may also detect it by doing a test referred to as a western blot (a gel protein electrophoresis). Thirdly by pcr (polymerase chain reaction) which ...Read more


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Which HIV tests promise earlier results? Is the HIV ag/ab 4th gen test not one of them?

Which HIV tests promise earlier results? Is the HIV ag/ab 4th gen test not one of them?

Rapid results: There are mini ELISA kits available with results in 15 minutes. And they are good! You could also go to your local health department to be tested or doctors office. If you ask me though. Don't be concerned with the rapidity that you get the results back because you may sacrifice accuracy. Just go to your doctor and have them run a Western Blot or conventional HIV screening test on your serum. ...Read more

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I had a hiv ag ab combo 4th gen test done at 3 weeks 6 weeks and 19 weeks are they conclusive still very scared?

I had a hiv ag ab combo 4th gen test done at 3 weeks 6 weeks and 19 weeks are they conclusive still very scared?

4th gen HIV tests...: ...are 100% conclusive any time 4 weeks or more after exposure. There is no basis for continuing to be frightened you have HIV. Assuming you haven't been reexposed more recently, your 6 week result was conclusive and your 19 week test unnecessary. Stop testing and do your best to move on without worry. Also test for gonorrhea, chlamydia, and syphilis if not done, much higher risk than HIV. ...Read more

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Hiv ag/ab combo : non reactive, patient s/co: 0.23 (ref : reactive >=1.0 s/co). What does this mean. After 1 year of exposure.

Hiv ag/ab combo : non reactive, patient s/co: 0.23 (ref : reactive >=1.0 s/co). What does this mean. After 1 year of exposure.

Not infected: S/co is a way of saying that your value is 23% of the cutoff that would make it positive. This does not mean you have a little bit of the virus, it's just the way that the test works in today's age of molecular medicine. ...Read more

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I was wondering is it possible to have HIV and not be detected in the HIV ag/ab combo testing? Is there a dormant phase? And for how long of dormancy?

I was wondering is it possible to have HIV and not be detected in the HIV ag/ab combo testing? Is there a dormant phase? And for how long of dormancy?

It depends...: The HIV antibody-antigen combo or duo test ("4th generation" test) is always positive by 4 weeks. If it has been that long or more since your last possible exposure, it is not realistically possible that you have HIV. Most people with HIV remain outwardly healthy for years, so it seems dormant. But not really. The virus is active, damaging the immune system and leading toward death if not treated. ...Read more

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I recently had a neg HIV AG/AB 4th GEN RFL blood test. Why does it say that a nonreactive result does not exclude it?

I recently had a neg HIV AG/AB 4th GEN RFL blood test. Why does it say that a nonreactive result does not exclude it?

Could be too early: Because the test doesn't become reliably positive until 4 weeks after exposure. Before that time, a nonreactive test result doesn't prove someone doesn't have HIV. But after 4 weeks, a negative 4th generation test is conclusive proof. ...Read more

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Wondering in 2012 I did a HIV 1/2ab test came back negative, in 2014 I did a HIV ag/ab test combo came out negative do I need retest monogamous 3 yrs?

You decide: This depends on how monogamous you believe your partner is. Nowadays for young adults, HIV testing is often something we simply do yearly, risk or no. ...Read more

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I tested negat 4 wks. Maybe more than 4wk w/ HIV ag/ab test and oraquick at home. I plan on getting testing again at 3 mo. Is this a good indication?

Can't tell: One cannot firmly diagnose HIV with blood test until around 3 months after the exposure although there are some tests promising earlier results. ...Read more

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Can low lymphocyte count 1477 18% affect a neg HIV Ag/Ab test done after 4 mths. I read on the net abt people with low imunity that need six mths. Plz h?

Can low lymphocyte count 1477 18% affect a neg HIV Ag/Ab test done after 4 mths. I read on the net abt people with low imunity that need six mths. Plz h?

Your test is valid: That advice is for the older generations of HIV testing. You are not HIV positive. If you doubt this, then you owe it to yourself to get a HIV RNA test and look directly for the virus and not any more antibody testing. ...Read more

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Is a HIV ag/ab eia and a hiv-1 Rna test conclusive at 5 months? I also had a 4th gen test 3 months ago both negative. Blood was cold if that matters

HIV negative: If your fourth generation test and RNA tests are both negative at 5 months after an HIV exposure, as long as you haven't had any other exposures in the meantime, then yes you would be considered HIV-negative. ...Read more

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With todays ultra sensitive modern ELISA tests, what use is the western blot for hiv? A few months ago I received a weakly reactive cmia HIV ag/ab test, a 4th generation HIV combo test, and this was followed by a negative western blot and a negative p24 t

False-positives: Screening tests are designed to be highly sensitive so they don't miss anyone with the disease. However, they can be so sensitive that they occasionally give a false-positive result. That is, the test appears positive for someone without the disease. The western blot, being time consuming and extra cost, is only used to make sure a positive is really a positive. Talk with your doc for more info. ...Read more

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Hi, had HIV-1 rna pcr @ 5 weeks & 5 months. And HIV ag/ab DUO at 1, 2, 4 & 6 months. Do I need further testing for HIV or do I need HIV-2 pcr or did the DUO rule it out?, or is it too rare to worry about in MI? I leave in Novi, MI. Thank you

HIV: Assuming what you have described is accurate, you do not have HIV infection and do not need further testing unless there have been subsequent exposures. Good luck and be careful out there. ...Read more

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Hiv p24 ag ab combo test at 28 days, 42 days and 62 days, some are negative. Quanto to be safe after 62 days?

Not a good test: P24 antigen testing is not the best way to rule out infection. The most sensitive test is a qualitative viral dna test, not usually performed. At 62 days HIV elisa may well be positive, if you were infected. Because sometimes antibodies are not formed until 90 days, you can complement by HIV RNA test that can detect down to 20 copies per ml of blood. ...Read more

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Hello, I did 2 times hiv test (ab+ag) roche method. 1) 2 weeks I got 0.157 2) 5 weeks I got 0.251 Must I redo or is conclusive?

Nucleic acid test: Get a HIV nucleic acid test. If the result is negative, repeat the test in 6 months. See a doctor for a proper evaluation. ...Read more

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What does a nonreactive/neg HIV 1/2 AG/AB 4th GEN/RFL mean? Why does it say it does not exclude HIV and that seroconversion is variable?

For the lawyers: Nobody knows how often the new HIV tests turn positive "late" because nobody really knows who's done what other risky stuff and not told about it. I'd accept negative / nonreactive results if the usual time frame for the test has lapsed, be thankful for good health, love safely from now on, and share the memory of whatever happened as something to be treasured. ...Read more

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Hello I had hiv 1and2 test at 6 months after exposure and hiv ab/ag at 3 months both negative and I have type 1 diabetes can diabetes change hivresult?

No: However, to be sure, you should get a HIV nucleic acid test, if that is negative, you would be free of HIV.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex, if you have sex. ...Read more

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Hello. Can type 1 diabetes cause a false negative hiv test I tested for hiv ab/ag at 3 months negative and hiv1, 2 at 6mnths negative Is it conclusive?

No and yes: HIV test is not affected by other disease conditions. A negative test at 6 months tells you that you didn't have the infection from that encounter. However it would not have ruled out HIV if you had been exposed to HIV infected blood or secretion subsequently. ...Read more

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Will acute or past infection of aids/HIV be detected by an HIV 1/2 AG/AB 4th GEN/RFL blood test?

Will acute or past infection of aids/HIV be detected by an HIV 1/2 AG/AB 4th GEN/RFL blood test?

Yes: If your last exposure was more than about a month ago. Whatever the result, love safely and live carefully from now on, and be a gentleman. ...Read more

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Iam male received oral and rubbing 95% of time was protected there were fungal infection and some scratches on thigh and testicles, after 50 days hiv ab/ag negative result took 24 hours only, is it accurate or it was rushed with cheap testing method?

Iam male received oral and rubbing 95% of time was protected there were fungal infection and some scratches on thigh and testicles, after 50 days hiv ab/ag negative result took 24 hours only, is it accurate or it was rushed with cheap testing method?

Low risk, valid test: There is no such thing as a "cheap" Ag/Ab test that is less reliable than others. And all the HIV blood tests are highly automated; they are almost impossible to screw up by lab error. Anyway, you had a zero risk exposure. You definitely did not catch HIV. ...Read more

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I took a 5th gen Ag/Ab HIV test 39 days post possible exposure. Result was non-reactive. Am I ok?

Conclusive HIV test: "Fifth generation" for an HIV test is marketing hype -- the manufacturer calls their new test 5th gen, but it's still bacially the same as all other 4th generation tests. Results of 4th gen HIV tests are usually conclusive after 4 weeks and always by 6 weeks (42 days). But 39 days is close enough; for sure you didn't catch HIV. ...Read more

Dr. Ed Friedlander
1,489 Doctors shared insights

Human Immunodeficiency Virus (Definition)

Human immunodeficiency virus (HIV) is a lentivirus (a member of the retrovirus family) that causes acquired immunodeficiency syndrome (aids), [1][2] a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections ...Read more


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