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Doctor insights on: Hiv 2 Proviral Dna Qual Pcr

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I had unprotected oral sex on me I saw no blood I have no sores I am circumsized I have tooken a HIV dna pcr test at 18 days and a 46 also a 4 week and 6 week duo test and a 8 week rapid test am I ok?

I had unprotected oral sex  on me I saw no blood I have no sores I am circumsized I have tooken a HIV dna pcr test at 18 days and a 46 also a 4 week and 6 week duo test and a 8 week rapid test am I ok?

You're OK: Oral sex is safe sex for HIV, with no proved transmissions by fellatio from mouth to penis, only rare ones penis to oral. You didn't need testing on account of this event and for sure not the multiple expensive ones you had. But the results from that combination of tests are conclusive. For sure you didn't catch HIV during that exposure and no further testing is needed. Best wishes and stay safe! ...Read more

Polymerase Chain Reaction (Definition)

Polymerase chain reaction is a method of finding a specific piece of dna and copying it over and over again until there is enough to study. The technique allows a scientist to detect very small amounts of dna in a swab sample then reproduce enough of it to study it. It is very sensisitive for detecting the presence of certain bacteria and is also used in doing other ...Read more


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Is my 8 wks 2 day PCR RNA + 4th Gen test negative conclusive for HIV infection after vaginal exp? Or do i need to test after 12 wks or it has to be after 13 wks? Pls answer, Thanks for any response

Is my 8 wks 2 day PCR RNA + 4th Gen test negative conclusive for HIV infection after vaginal exp? Or do i need to test after 12 wks or it has to be after 13 wks? Pls answer, Thanks for any response

Relax, Mike: I understand that you're a man worried about HIV after an unprotected episode of intercourse with a woman. The nucleic acid tests are almost always positive by this time -- we can't even estimate the frequency of their turning positive only at 12 weeks because history isn't always accurate. Retest only if you or someone close to you is obsessed over it. Love wisely and well from now on. Cheers. ...Read more

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Does NAT test accurate for detecting HIV-2? is there a PCR specific for HIV2 or Hiv PCR detect both as I was told by my HP there is none specific

Does NAT test accurate for detecting HIV-2?
is there a PCR specific for HIV2 or Hiv PCR detect both as I was told by my HP there is none specific

HIV is a virus, thus: no test is perfectly accurate. Study: http://www.questdiagnostics.com/testcenter/testguide.action%3Fdc%3DTG_HIV_Management & https://www.google.com/#q=HIV%20testing for reasonable information on current clinically available technology. You are on the right track to study the issues yourself. You have the most vested interest & are your own primary medical decision maker (physician if you will). ...Read more

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A friend had hiv test at 6 months last exposure negative,now he had a pos for hiv-2 at 7 months.He also did a pcr at 4 months.can it be false positive?

A friend had hiv test at 6 months last exposure negative,now he had a pos for hiv-2 at 7 months.He also did a pcr at 4 months.can it be false positive?

Probably false pos: HIV-2 is very rare outslide the area of west Africa where it originated (Cameroon), although I don't know about Albania for sure. The PCR should have picked up HIV-2 as well as HIV-1. So your freind's HIV-2 test probably is false positive. He should see an infectious diseases or HIV expert to sort it out. ...Read more

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Can hiv-1 RNA PCR detect hiv-2 at some point or can not detect?If you consider Poland, can you exclude HIV possibility with hiv-1 RNA PCR test only?

Can hiv-1 RNA PCR detect hiv-2 at some point or can not detect?If you consider Poland, can you exclude HIV possibility with hiv-1 RNA PCR test only?

HIV Online: We are very experienced here with what we call HIV panic. There is little we will say that will ease your panic. HIV 1 in the disease you are at risk for in Poland in general. Your HIV RNA test is negative. If you cannot get past this worry then go get an HIV 1/2 antibody test with the P24 antigen test as well. Then test every twelve weeks. And if you are at risk get on Truvada (emtricitabine and tenofovir) to prevent. ...Read more

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Hi, had HIV-1 rna pcr @ 5 weeks & 5 months. and HIV ag/ab DUO at 1, 2, 4 & 6 months. Do I need further testing for HIV or do I need HIV-2 pcr or did the DUO rule it out?, or is it too rare to worry about in MI? I leave in Novi, MI. thank you

HIV: Assuming what you have described is accurate, you do not have HIV infection and do not need further testing unless there have been subsequent exposures. Good luck and be careful out there. ...Read more

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Hiv-1 RNA PCR result is undetected,worried about hiv-2 in Germany. Dr didnt see necessary to take antibody test even at w12.What should I do?

Hiv-1 RNA PCR result is undetected,worried about hiv-2 in Germany. Dr didnt see necessary to take antibody test even at w12.What should I do?

Wait: You must wait. Or get an HIV 1/2 antibody test but know you will have to repeat it in the future. At twelve weeks it cannot be 100% accurate. in the future if you have a high risk exposure there is a treatment to prevent infection if started within 72 hours. If you have repeated high risk exposures there is a treatment to take before exposure to prevent infection. ...Read more

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I had unprotected oral sex 8 week ago I had 2 HIV DNA PCR test at 18 days and 46 days negative and 2 fourth generation test at 28 days and 42 days neg?

I had unprotected oral sex 8 week ago I had 2 HIV DNA PCR test at 18 days and 46 days negative and 2 fourth generation test at 28 days and 42 days neg?

HIV: The overwhelming probability is that you did not get HIV infection. You do not say whether the oral sex was done to you (in which case you were not in any significant risk), or whether you did it to a woman (not a risk). If you did to another man and semen hit the back of your throat that is a good way to become infected so in the future make sure he has a condom on. You are going to be fine. ...Read more

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Can a quantitative HIV DNA test that looks for the virus differentiate HIV 1 from HIV 2 ?

No: This is determined predominantly by antibody testing rather than by PCR for HIV RNA (This is an RNA virus). The latter test does not differentiate serotypes. Type 2 is very rare outside of Africa and seems more difficult to transmit. There are also numerous subtypes of both Types 1 & 2 and this becomes quite complex since this virus mutates continuously. ...Read more

Dr. Marvin Ott
16 doctors shared insights

Hiv (Definition)

Hiv infection is caused by a retrovirus....This retrovirus binds to CD4 cells (for the most part). You may detect the virus by several different methods. An elisa test (enzyme linked immunosorbent assay). You may also detect it by doing a test referred to as a western blot (a gel protein electrophoresis). Thirdly by pcr (polymerase chain reaction) which ...Read more


Dr. Ed Friedlander
1,461 doctors shared insights

Human Immunodeficiency Virus (Definition)

Human immunodeficiency virus (HIV) is a lentivirus (a member of the retrovirus family) that causes acquired immunodeficiency syndrome (aids), [1][2] a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections ...Read more