Doctor insights on:
Hiv 2 Ab W Reflex To Immunoblot
Is 4th generation ag/ab conclusive for BOTH hiv-1 & hiv-2 after 6 months (& multiple tests before this) of unprotected sex? Is further testing needed?
Hiv infection is caused by a retrovirus....This retrovirus binds to CD4 cells (for the most part). You may detect the virus by several different methods. An elisa test (enzyme linked immunosorbent assay). You may also detect it by doing a test referred to as a western blot (a gel protein electrophoresis). Thirdly by pcr (polymerase chain reaction) which ...Read more
Will a 4th gen hiv test detect hiv-2 antigens? I had some exposures with an african man. Last test at 18 week ag/ab.When will hiv 2 be conclusive ?
Hi I had HIV-1 rna pcr @ 5 wks & 5 mths & HIV ag/ab DUO at 1, 2, 4 & 6 mths. Do I need further testing for HIV-2 or am I safe? I'm in metro Detroit.
Hi, had HIV-1 rna pcr @ 5 weeks & 5 months. and HIV ag/ab DUO at 1, 2, 4 & 6 months. Do I need further testing for HIV or do I need HIV-2 pcr or did the DUO rule it out?, or is it too rare to worry about in MI? I leave in Novi, MI. thank you
Depends on behavior: If you are in west africa and do not take protective measures and precautions pretty good chance to get infected. ...Read more
Different types: Hiv-1 and hiv-2 are different types of hiv. Hiv-1 comprises the majority of HIV infection in the world. Hiv-2 is usually found in africa, and rarely elsewhere. Both hiv-1 and hiv-2 can usually be detected through the usual hiv-1/2 antibody test. Hiv-2 is typically less aggressive/virulent and less transmissible (more difficult to pass from one person to another). ...Read moreSee 1 more doctor answer
Source of infection: Hiv-1 is the more common form of HIV in the usa/europe, while hiv-2 occurs predominantly in west african nations, and former portuguese colonies, such as angola, mozambique, and brazil, and in parts of india (goa, maharashtra). Many hiv1 medications are effective against hiv2. Usa cases of hiv2 are projected to be several hundred, although estimates vary. ...Read more
Immunoblot: Western blot is an antibody detection test. Viral antigens (the protein coat of hiv) are immobilized in a matrix (gel). These are then transferred to Cellulose membrane and a persons serum is exposed to it. Antibodies in the serum then bind to the proteins (ie gp120). Antibodies that do not attach are washed away. Chemicals are then applied to allow visualization of the bands. ...Read more
No, but depends: No, it is not necessarily true that homosexuals are more likely to transmit hiv-1 and hiv-2 sexually. It ultimately comes down to the risk behavior of the specific sexual act that leads to HIV infection. Unprotected anal intercourse is the most risky, but whether that occurs with two men or a man and woman, the risk is the same. Unprotected vaginal intercourse is less risky followed by oral sex. ...Read moreSee 2 more doctor answers
Can the inst hiv-1/hiv-2 antibody rapid test be reliable after 62 days to possible HIV exposure? Test results were negative. Could this be reliable?
HIV Testing: No, unfortunately. For the routine HIV antibody tests you need a minimum of three months or 90 days and a safe view of six months. However there is testing that is much more reliable. This is the HIV pcr dna testing. This test, if negative after 21 days post exposure is 100% accurate if negative. ...Read more
Is 30 day DUO conclusive or I have to wait for HIV-2 possibility. Also, I got a unprotected bj from a high risk partner, what are the chances of HIV?
It's conclusive...: ...and anyway there has never been a proved case of HIV transmission mouth to penis. You didn't need testing if that was your only potential exposure. But the DUO test is conclusive at 4+ weeks and covers HIV2 -- which is so rare in the US that it doesn't matter, with almost all cases in persons who caught it in Africa and their long-term sex partners. So no worries, don't have another test. ...Read more
Human immunodeficiency virus (HIV) is a lentivirus (a member of the retrovirus family) that causes acquired immunodeficiency syndrome (aids),  a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections ...Read more
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