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Doctor insights on: Histology Of Lymphoid Tissue

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Weakly prolif. Endo. W foci of stromal and glandular breakdown. Rare lymphoid aggregates found in portions of biopsy in context to myxoid stroma seen ?

Weakly prolif. Endo. W foci of stromal and glandular breakdown. Rare lymphoid aggregates found in portions of biopsy in context to myxoid stroma seen ?

No ovulation: This is a description of endometrium that has been in the proliferative (growing or recovery) phase for too long. That is the phase which normally preceeds ovulation. After ovulation, the endometrium moves into the secretory phase during which an embryo can be received if pregnancy takes place; otherwise a normal menstrual phase (period) begins. Hormonal treatment may be necessary if out of order. ...Read more

Tissue (Definition)

The body is composed of tissue that are classically described as beiing derived from three basic embyonic layers known as the endoderm, mesoderm and ectoderm that then differentiate into the structures that compose the body such as skin, soft tissues, bone, muscle, organs, etc. Stem cells are not differentiated and have the potential to ...Read more


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Mesothelioma biopsy says 'portions of fibrous tissue infiltrated by malignant cells forming nests. tumor cells +'ve for CK7 and calretinin. prognosis?

Mesothelioma biopsy says 'portions of fibrous tissue infiltrated by malignant cells forming nests. tumor cells +'ve for CK7 and calretinin. prognosis?

Marker not prognosis: CK7 and calretinin are used to verify that the tumor is mesothelial in origin (versus adenocarcinoma of the lung). It does not provide information about prognosis. Factors associated with pleural mesothelioma prognosis include: functional status, blood counts, histology (epithelial best vs fibrosarcomatous poorest), and tumor size (degree of involvement of pleural cavity). Several new trials. ...Read more

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Fragments of hyperplastic squamous epithelium with basal zone hyperplasia. Underlying stroma moderate infiltrate of chronic inflammatory cells. Bad?

Fragments of hyperplastic squamous epithelium with basal zone hyperplasia. Underlying stroma moderate infiltrate of chronic inflammatory cells. Bad?

Not cancer: Nothing in this dscription says 'cancer'. In fact, nothing in this description says it's other than just a palce where you scratched for a week or so because it itched. The key is the clinical correlation. ...Read more

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What are characteristics of soft tissue sarcomas?

What are characteristics of soft tissue sarcomas?

Wildly variable: "soft tissue sarcomas" encompass over 100 different types of cancers, depending on what tissue it started in (fat, supporting tissue, muscle, bone, guts, etc.); within each tissue type, there are dozens of different cancers. In general, they are lumps under the skin, sometimes with overlying skin color or contour changes. Often neglected because not painful. See a good surgeon, and good luck! ...Read more

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What does increase cellularity of lamina propria w eosin, lymphoid nod, and paneth cell metaplasia mean in colonic biopsy of terminal ileum?

What does increase cellularity of lamina propria w eosin, lymphoid nod, and paneth cell metaplasia mean in colonic biopsy of terminal ileum?

Chronic inflammation: Paneth cell metaplasia occurs when the bowel mucosa undergoes chronic inflammatory damage and then regenerates. The findings are commonly seen in association with inflammatory bowel disease (ulcerative colitis or crohn's). ...Read more

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Biopsy report of buccal mucosa: infiltrating moderately differentiated keratinizing squamous cell carcinoma. What does this means.?

Biopsy report of buccal mucosa: infiltrating moderately differentiated keratinizing squamous cell carcinoma.  What does this means.?

Needs treatment: Means you have cancer of oral cavity ( buccal mucosa ) from your description appear to be localised you will have good prognosis needs further work up for staging &care , by surgical excision for localized small area, or chemo radiation , discuss with your physicians and please do not delay . Good luck. ...Read more

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Histological section shows mainly decidualised endometrial tissue with hyperplastic glandular component specimen: uterine evacuation?

Histological section shows mainly decidualised endometrial tissue with hyperplastic glandular component

specimen: uterine evacuation?

Hyperplasia: The sample you describe is suggestive of overgrowth of tissue in the uterus due to irregular menstrual cycles. It is seen in women who go for > 6 months without bleeding and suggests overstimulation due to estrogen effect. If left untreated, it could lead to endometrial cancer. Still, it is very slow growing but needs to be monitored. ...Read more

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Rare lymphoid aggregates found in myxoid stroma. What does this mean? Endo biopsy

Rare lymphoid aggregates found in myxoid stroma. What does this mean? Endo biopsy

Nothing by itself: If this is included in a description of a tumor, then the full diagnosis of the tumor needs to be included. If this is a description of a non-neoplastic mucosa, it requires a non-tumor diagnosis. This is only a part of a pathology report, meaningless without the larger picture. You have a right to a full explanation from your caregiver, who has a "path" course in med school. Best wishes. ...Read more

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Dear Sir FNAC result "Smear consists of fibrofatty tissue with few lymphocytes and polymorphs suggestive of inflammed lipomatous lesion"?

Dear Sir
 FNAC  result  "Smear consists of fibrofatty tissue with few lymphocytes and polymorphs suggestive of inflammed lipomatous lesion"?

May need core biopsy: FNAC is often inadequate to make a proper diagnosis, especially if you suspect cancer. if you have a tumor, you should go and see a good surgeon who deals with cancer. He may do a core biopsy which gives more tissue than a FNAC. I am afraad you will need a repeat biopsy but seek a second opinion for finding out what you have wrong ...Read more

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What distinguishes cancer cells from the cells of benign neoplasms?

What distinguishes cancer cells from the cells of benign neoplasms?

Disordered growth: Benign tumors grow locally and do not spread. Under the microscope, the cells look like the gland they are from and they are not invading. Cancer cells have disordered growth, frequently do not look like the originating gland and show invasion. ...Read more

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Neoplasm of lymphoid tissue, what is the medical term?

Neoplasm of lymphoid tissue, what is the medical term?

Lymphomas/Leukemias: Lymphomas like Hodgkin's/Non Hodgkin's Lymphoma OR some Leukemia of lymphoid cell lines like CLL(chr lymphocytic leukemia] , ALL/acute lymphoblastic leukemia etc ...Read more

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Which distinguishes cancer cells from the cells of benign neoplasms?

Which distinguishes cancer cells from the cells of benign neoplasms?

Genome destabilized: The key to cancer is that enough mutations have accumulated to render the genome itself unstable. Eventually a clone will acquire the ability to invade and spread. We can pick this up using molecular biology techniques. They also look different, but it takes a pathologist several years to learn to tell all the subtleties. ...Read more

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Endometrium is tubular to elongated endometrial glands, separated by dense stroma, and focal crowding of stroma with areas of hemorrhage, nonsecretory?

Endometrium is tubular to elongated endometrial glands, separated by dense stroma, and focal crowding of stroma with areas of hemorrhage, nonsecretory?

Abnormal bleeding: The biopsy you described suggests that you are not having regular cycles and your doctor wanted to confirm that there was not a precancerous condition in your uterus. If you go for long periods of time without a menstrual cycle and still have a thick endometrium, it can become precancerous. You may need to take medications to regulate your cycles to prevent these changes. ...Read more

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What is the difference between a histology and a pathology report?

What is the difference between a histology and a pathology report?

Unclear question: Histology usually refers to microscopic features of a tissue. Pathology report has interpretation of the findings and is usually more than just histology. Pathology reports also deal with blood tests, microbial cultures and genetic tests. ...Read more

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