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Doctor insights on: Histamine Itchy Allergy Response

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Histamine (Definition)

Histamine is an organic nitrogen compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. Histamine triggers the inflammatory response. As part of an immune response to foreign pathogens, histamine is produced by basophils and by mast cells found ...Read more


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2 days ago got tested for allergies (scratch test) only spots w/reaction were histamine+mold. Now there are red spots (not the pricks) itchy, causes?

2 days ago got tested for allergies (scratch test) only spots w/reaction were histamine+mold. Now there are red spots (not the pricks) itchy, causes?

ST reaction: The skin test response to allergen may start within minutes followed by a delayed response from 2-8 hrs later. The delayed reaction may linger for a few days. However the reaction consists usually of a raised wheal and not just redness. Are your red spots raised or flat? ...Read more

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Which is the best anti-histamine to buy for itchy watery eyes from allergies?

Which is the best anti-histamine to buy for itchy watery eyes from allergies?

Several: There are several to choose from, but the most effective are Cetirizine (zyrtec) and fexofenadene (allegra). You might also consider an over the counter antihistamine eye drop such as ketotifen. ...Read more

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Red itchy hands that are peeling. No response to benedryl. No known allergies. What could it be?

Red itchy hands that are peeling. No response to benedryl. No known allergies. What could it be?

? Contact dermatitis: benadryl (diphenhydramine) won't help, keep your hands well hydrated and moisturized, OTC anti itch cream, if that doesn't help please see your doctor ...Read more

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If I'm super itchy, will anti-histamines work?

If I'm super itchy, will anti-histamines work?

Depends: Most itchy skin rash are not mediated by histamine and thus whether it would respond to histamine or not would depend on the mechanism causing it. There is no harm in trying antihistamine even up to 4x the usual dose. The sedating ones tend to work better on itching due to sedating effect. Consult your doctor if antihistamine does not work. ...Read more

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Some kind of allergy on skin. Very itchy?

Some kind of allergy on skin. Very itchy?

See dr.: Rashes are tough to DX over the computer, try Benadryl (diphenhydramine) to start for the itch and get it evaluated for a dx. ...Read more

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Could i be itchy all over due to pet allergies?

Could i be itchy all over due to pet allergies?

Possible: The only doctor that could answer this is an allergist. You could possibly have dry skin from using too much soap, taking too many hot showers and not using moisturizer. ...Read more

Dr. John Chiu
2,479 doctors shared insights

Allergies (Definition)

Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more