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Doctor insights on: High Wbc Low Platelets

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Low Platelets (Definition)

In the blood. They "bud" ie break off from cells in the bone marrow called megakaryocytes. A normal platelet count is 140-400. Platelets are the first line of defense in blood vessel bleeding. They "plug holes" until the coagulation proteins can begin ...Read more


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Several blood tests came back abnormal. High wbc-12, 000, low platelet-110, but RBC normal-15. Thyroid and several other tests abnormal. What is wrong?

Several blood tests came back abnormal. High wbc-12, 000, low platelet-110, but RBC normal-15. Thyroid and several other tests abnormal. What is wrong?

Unanswerable: There is not enough data here to give you any real or valid answer. You are not well. You may have several conditions at once. I would be staying real close to your physician and following all advice and treatment plans. ...Read more

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5 year old with normocytic anemia. Normal reticulocyte and ferritin. High WBC and platelets. Low hemoglobin. What could be the cause?

5 year old with normocytic anemia. Normal reticulocyte and ferritin. High WBC and platelets. Low hemoglobin. What could be the cause?

Sketchy picture: how is your child doing apart from those figures? can be just common iron deficiency anemia, and how high are the platelets or the WBCs? also common to have some elevations with any concurrent infection. If your child is doing fine otherwise, disregard those numbers and trust your doctor, we treat patients not lab results, best wishes for yourself and your child ...Read more

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5 year old has persistent normocytic anemia. High WBC, platelets, low RBC and hemoglobin. Normal MCV, MCH, ferritin and reticulocyte. What's the cause?

5 year old has persistent normocytic anemia. High WBC, platelets, low RBC and hemoglobin. Normal MCV, MCH, ferritin and reticulocyte. What's the cause?

Need more tests,,,: This is hard to determine as this is the case of a child. Other tests like a peripheral blood smear might help to find the cause. It would be best to see the doctor, preferably a pediatrician, for more tests and an exam. Best of luck. ...Read more

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What conditions could cause high monocytes, lymphs, bezors, low wbc and low platelets? Also fluctuations?

What conditions could cause high monocytes, lymphs, bezors, low wbc and low platelets? Also fluctuations?

Abnormal blood cell: Bezors probably has nothing to do with mono/ lymphocytosis. Having said that it is inadequate information to connect the dots. Detailed history and examination is required otherwise it would be a case handled by GOOGLE doctor. Have it evaluated by a physician with complete history and physical ...Read more

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Low platelets, high SEG, low lymphocytes, normal WBC. Feel unwell. History of Lyme. Recent new tick bite. Reinfection? Symptoms similar to before.

Low platelets, high SEG, low lymphocytes, normal WBC. Feel unwell. History of Lyme. Recent new tick bite. Reinfection?  Symptoms similar to before.

Lyme disease: You do not say what your prior symptoms were or whether or not the diagnosis was ever confirmed. If you have had a typical rash, have symptoms of cardiac, neurological or arthritic nature you should be seen by a doctor familiar with this disease and evaluated before being treated. ...Read more

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Slightly low WBC, low platelets, low neutrophils ,no baso's. Elevated lymph's and mono's. Does that mean bone sarcoidosis is back and active?

Slightly low WBC, low platelets, low neutrophils ,no  baso's. Elevated lymph's and mono's. Does that mean bone sarcoidosis is back and active?

Give us the numbers: Medicine is quantitative....actual numbers are essential to make any diagnosis. Slight changes mean very little. They can be misleading at best. So send us the exact numbers of your blood counts, then we can help you to interpret their meaning. Also tell us more about the past history of Sarcoidosis that you have mentioned ...Read more

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I have mildly low WBC and mildly low platelets. My platelets (auto) are 135 on a range of 143-398. My WBC is 3.90 (range 4.16-9.95). What is cause?

Low platelets, WBC: There are many possible causes of low platelets and low WBC. Some medications can do this, some viral infections and many other causes. It is best to see your doctor regularly to follow up on these tests to make sure they are not decreasing to a serious level. Then, you may need more extensive testing. ...Read more

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Recent labs came back with low platelets 115k and WBC 3.55 (scale 3.70-11.0). I was feeling weak that day. Other labs ok. Should i worry of cancer?

Recent labs came back with low platelets 115k and WBC 3.55 (scale 3.70-11.0). I was feeling weak that day. Other labs ok. Should i worry of cancer?

No: Why you worry about cancer? These result could be due to recent viral infection or after "cold" and just have temporary effect. Give yourself few days of rest and see what happen. Be well. ...Read more

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CBC/Diff Ambiguous Default WBC 3.0 Low,Platelets 100 Alert and Neutrophils ( Absolute ) 1.3 Low what to do and from what is the cause please?

CBC/Diff Ambiguous Default WBC 3.0 Low,Platelets 100 Alert and Neutrophils ( Absolute ) 1.3 Low what to do  and from what is the cause please?

Multiple poss: Older labs and why done would help. This can be something as simple as lab error which is very common. The next most common cause would be a viral illness causing borderline labs. This can also be a sign of an early serious infection or bone marrow problem. These labs should be repeated in a few days to see if changing. If signs if infection, fever or bleeding see doctor or go to ER immediately. ...Read more

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Are borderline low platelets (174x10E3/ul) and 2 petechiae on abdomen suggestive of leukemia? WBC, RBC, differential all normal and feel fine. Thanks!

Are borderline low platelets (174x10E3/ul) and 2 petechiae on abdomen suggestive of leukemia? WBC, RBC, differential all normal and feel fine. Thanks!

Not leukemia: Petechiae due to low platelets would require a much lower platelet count, under 20,000 or so and often lower than that. So whatever the marks on your abdomen, they aren't petechiae due to low platelets. And with the rest of your blood counts normal, leukemia should not be on your mind. See your doctor if you remain concerned, but I see no reason for worry. ...Read more

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I h2ad a CBC test done and I had low WBC and platelets. My platelets were 137. Is it dangerous to be on Coumadin (warfarin) with such low platelets?

I h2ad a CBC test done and I had low WBC and platelets. My platelets were 137. Is it dangerous to be on Coumadin (warfarin) with such low platelets?

Nit necessarily: Usually plarelet counts over 100,000 are not associated with abnormal. bleeding The bigger question is why you are on coumadin (warfarin) Talk ti your doctor for concerns ...Read more

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Few months ago CBC with low rbc, wbc, hemoglobin, hematocrit, platelets. Since then CBC normal, but some low platelets. Often feel achy, could be hiv?

Few months ago CBC with low rbc, wbc, hemoglobin, hematocrit, platelets. Since then CBC normal, but some low platelets. Often feel achy, could be hiv?

HIV does not Hide: If you are worried about an HIV infection then you go get an HIV test. HIV is diagnosable by testing from seven days after exposure onwards with the correct tests. It does not hide and we no longer need to worry about ambiguous symptoms. If your HIV tests are negative then I do not understand the concern. There is nothing in a CBC test that would represent an early HIV infection. ...Read more

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Pediatric cancer? low RBC, low WBC, low platelets, low IGM, high MCV, low neutrophils, low monocytes and low eosinophils, occasional myelocytes,

Pediatric cancer? low RBC, low WBC, low platelets, low IGM, high MCV, low neutrophils, low monocytes and low eosinophils, occasional myelocytes,

Tough set of labs: Suppression of multiple cell lines certainly is a concerning finding on a CBC. Yes, there are pediatric cancers that may present with this type of blood test results. Talking to your heme/onc specialist as soon as possible would be advisable! But don't jump to conclusions because a specialist with the "whole picture" may give you a very surprising answer! ...Read more

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I'm a 37m. I have a constant high bilirubin (~2.1mg/dl), and for several years, high mpv (~13.4fl), and low platelets(140-160k). What does this mean?

I'm a 37m. I have a constant high bilirubin (~2.1mg/dl), and for several years, high mpv (~13.4fl), and low platelets(140-160k). What does this mean?

Probably nothing: I'm going to assume you are not taking any medications that will raise your bilirubin, and do not have a mild birth defect causing hemolysis. You probably have gilbert's non-disease. Your physician knows the workup, which is simple -- if you turn a bit more yellow if you skip a few meals, you're basically got the diagnosis. I would not be worried about the platelets, but monitor them. ...Read more

Dr. Liawaty Ho
1,055 doctors shared insights

Thrombocytopenia (Definition)

deficiency of platelets in the blood. This causes bleeding into the tissues, bruising, and slow ...Read more


White Blood Cell (Definition)

Body blood cell that responds to inflamation or infection or ...Read more