Doctor insights on:
High Vitamin B6 Blood Levels
I have neurological symptoms, 30 lesions on a brain mri, and high vitamin B6 blood levels (86ng). Can high B6 levels cause brain lesions?
Not a problem: I presume that this is because you are ingesting a large amount of b6, probably through supplements but perhaps via diet. B6 is not hazardous unless you take large amounts for a long time, generally 250 mg/day or more, or it may cause neuropathy. High levels just mean you have more than most people but is not dangerous. ...Read more
Why did you test for it? And why did you start it?
It is a water soluble vitamin so you can reduce the dose to normal range. ...Read more
I am 33 weeks pregnant and my routine blood work showed very low levels of Vitamin B6 (Pyridoxal 5-Phosphate: 12.8 nmol/L). VitB12 & Folate were within normal range. Is this dangerous for my baby? Is the result reliable? I haven't spoken to my OB yet...
Probably not: Folate (folic acid) and Vit B12 deficiency is associated with more serious complications likeneural tube defects and spina bifida etc. While B6 is an important vessential vitamin, its effect on pregnancy is not as dramatic and usual prenatal supplement should satisfy its requirement. ...Read more
35 yr-old started with paresthesias 4 yrs ago, that generalized to include autonomic symptoms and gastroparesis, looking for effective treatment.....?
Neuro exam?: Interesting case, but I'd like to know about her neuro exam. By the history, her symptoms haven't progressed in a length-dependent manner (especially given the facial sensory involvement) and this points me toward a sensory neuronopathy aka sensory ganglionopathy. These patients would be expected to have proprioceptive impairment-- if she is still a dance instructor, I doubt her proprioception is impaired. If her neuro exam and nerve conduction study are truly normal, I suspect any additional testing will be normal as well. ...Read more
Could a Vitamin B6 level of 58 have cause my polyneuropathy and severe pain? I don't take an supplements and don't know how it could be so high.
I have high levels of vitamin B6 and b1. I don't take vitamin b supplements and my multi vit has 3.2mg of B6 in it. Suggestions on why it's high?
Check your diet: Some foods conatin high level of vitamins b6 and b1. Cod, salmon, halibut, trout, tuna and snapper; chicken, turkey, beef, and pork; bell peppers, spinach, baked potatoes (skin included), green peas, yams, broccoli, asparagus and turnip greens are just some examples of fish which contain high levels of b6. Eating vitamin b2-enriched cereals, red meats or leafy vegetables, you can get vitamin b2. ...Read more
Many thanks for your helpful response yesterday. I did have neck& thoracic mris– negative. Should I still get a dir? Also, could there be a tie btw mri, symptoms & high vitamin B6 levels?
Don't know: You need to see a doctor and have them fully evaluate you with history, physical and allowing you to explore issues with any questions you may have. You sound quite intelligent, and they should be able to provide you with good responses. Good luck and hope this all gets worked out. ...Read more
56 year-old woman notices radicular pain after taking vitamin B6 supplement for three years.....?
B6 toxicity is well recognized:
There are a few questions that need to be asked in this case. Exactly how much B6 was the patient taking? According to recommended standards 200mg daily is the limit. Toxicity is thought to occur at levels of 1000mg. Daily and above though much lower have been reported on rare occasions (100-300mg). Secondly, what exactly was the quality of her pain? Described symptoms of neural toxicity involves sensory neuropathy described mainly as burning dysesthesias and numbness. The case talks about a RADICULOPATHY. That is typically not the same type of pain as we find in chemical toxicities. Pain in the feet could very well be dysesthesias but the history could be a bit more specific there in order to attach more positive points for B6 sequelae.
http://www. Ncbi. Nlm. Nih. Gov/pubmed/16320662 ...Read more
Many things: Ebv positive can just mean past exposure. A low vit d 3 indicates a need for vit d3 but one should look for stressors that increase free cadmium that breaks down 25-oh vit d3. A high level of vit b6 may just mean that one took a supplement with b-6 close to the time the blood was drawn. Develop a healthy life style, avoid dairy, wheat, and sugar which can cause diarrhea and yeast overgrowth. ...Read more
How do you that it:
Is due to B6 deficiency. You ought consult a neurologist to determine the cause of peripheral neuropathy and treat the cause. Excess of B6 can itself cause neuropathy. You may visit these two sites for information and then discuss the matter with your doctor.
http://www. Mayoclinic. Org/drugs-supplements/vitamin-b6/background/HRB-20058788
https://www. Ncbi. Nlm. Nih. Gov/pubmed/16320662 ...Read more
Can Vitamin B2 high intake (400mg daily) causes Vitamin B6 deficiency? I have muscle twitching in legs and I suspect vitamin b6 deficiency
No: No it cannot and it is highly unlikely B6 is related to your symptoms. ...Read more
Could schistosomiasis be related to carcinoid sy? Why carcinoid tumor produce elevated serotonin? How does it impact vitamin B6 as well as b3? Ty
No: Most stones are caused by crystallization of calcium oxalate. The most common antidote is magnesium. Uric acid actually comes from the metabolism of sugar and vitamin b1, which works closely with magnesium would be more likely to help rather than b6. Avoidance of sugar may be a key factor. ...Read more
Possibly: The research was done in 1972 on animals. Other nutrients may be even more important. The goal is to prevent deficiencies. Zinc is very important for the production of Progesterone and vital for the developing fetus. Vitamin d deficiency is very common and restoring vitamin d to normal levels increases successful pregnancies. Eat healthy, sleep well, de-stress and move frequently. ...Read more
From excessive doses: In general, vitamin b6 is extremely safe and well-tolerated, though it may cause stomach upset in some (esp. If taken without food. However, taking high doses of b6 daily for months (usually at least 1000 mg but in some as low as 200 mg) can cause toxicity symptoms, most commonly peripheral neuropathy (tingling & numbness) also headaches, fatigue & irritability, which will dissipate upon stopping b6. ...Read more
100 mg/day for adult: Chronic administration of 1–6 g oral pyridoxine (vitamin b6) per day for 12–40 months can cause severe and progressive sensory neuropathy characterized by ataxia (loss of control of bodily movements). Nevertheless, an upper limit of 100 mg/day for adults is considered safe. ...Read more
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