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Doctor insights on: High Sgot And Sgpt Levels And Methotrexate

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Sgot 66 &sgpt 55 how can it be reduced? And how to protect the liver? Since am taking 20 mg methotrexate and 5 mg folic acid!

Sgot 66 &sgpt 55 how can it be reduced? And how to protect the liver? Since am taking 20 mg methotrexate and 5 mg folic acid!

Se details: Elevated liver tests suggest Methotrexate toxicity. The only treatment is to reduce the dose of methotrexate. The use of leucovorin the day after the Methotrexate may also help if the Methotrexate dose cannot be reduced. Speak with your doctor. ...Read more

Methotrexate (Definition)

Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more


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Sgot 22 and sgpt 32 I have RA and taking 15 mg of methotrexate every saturday and folic acid every sunday. Should i be concerned about my liver?

Sgot 22 and sgpt 32 I have RA and taking 15 mg of methotrexate every saturday and folic acid every sunday. Should i be concerned about my liver?

Methotrexate: Methotrexate has many complications. It can affect the lung, liver, and bone marrow. Initial period required close monitoring for bone marrow suppression, liver injury. Previously, this medication was recommended to have periodic liver biopsy to assure patients can handle it. Nowadays, some questioned this approach. With periodic lft (liver lab work) and ultrasound might be sufficed. ...Read more

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I have high sgot and sgpt levels. 180 iu/l and 372 iu/l respectively. Please advice.

I have high sgot and sgpt levels.
180 iu/l and 372 iu/l respectively.
Please advice.

Workup: If two weeks off med and alcohol doesn't drop them to normal, you should be screened for hepatitis b and c, hemochromatosis, wilson's, antitrypsin deficiency, and autoimmune hepatitis. All are treatable and are likely to kill you if missed. If none are present, a new lifestyle focused on aerobic fitness may be just the thing to make you feel fantastic and get those liver enzymes in the good range. ...Read more

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Is livogen xt 100 mg once a day safe in 33 weeks pregnancy.? My Tlc is as high as 12,400 & my Sgot and sgpt levels are also high, is my baby at risk

Is livogen xt 100 mg once a day safe in 33 weeks pregnancy.?
My Tlc is as high as 12,400 & my Sgot and sgpt levels are also high, is my baby at risk

Depends: Livigen is iron and frolic acid and would be fine in a normal pregnancy. The abnormal lab values are concerning and I would need to know why they are elevated to say for sure that anything is safe. Good luck. ...Read more

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What is the cure for high sgpt and sgot levels?

Elevated liver funct: I can't say there is a cure for elevated liver functions , but we can treat the condition. First of all we need to find out the cause. You need to see your physician for a comprehensive history and physical exam , history of exposure to toxin, infections, drug history, diet history. You may need to have a liver US and maybe a fallow up liver CT. ...Read more

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My father is having high sgpt and sgot level please let me know what can be the causes and what can be the cure?

Liver issues: Those are liver enzymes. It's elevation has many possible reasons: infection, drug-induced, excessive alcohol consumption, mechanical obstruction, tumor, to name a few. ...Read more

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Can you tell me is high sgpt and sgot level fatal?

Liver disease: The higher the level sicker the liver as a rule, but what is more concerning is if the prothrombin time elevates. This is caused by a liver that is unable to produce clotting proteins and is a very concerning sign for liver failure. ...Read more

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I have high levels of triglycerid and ALT (sgpt) and AST (sgot). What does this mean?

I have high levels of triglycerid and ALT (sgpt) and AST (sgot). What does this mean?

Possibly fatty liver: Triglycerides are very long chains of repeated fatty acid molecules, that are intermediary products of fat and carbohydrate metabolism. They function as building blocks for various parts of the cell. When they are elevated, it may be genetics, diet, fat intake, or overweight condition all at play. Alt & ast are liver enzymes. In this case, the most likely meaning is fatty liver. ...Read more

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Hi i am 28 year old male my sgpt level is 108,and sgot 48,all other LFT values are normal,and have slightly high cholesterol. for the past 5 months i ?

Hi i am 28 year old male
my sgpt level is 108,and sgot 48,all other LFT values are normal,and have slightly high cholesterol. for the past 5 months i ?

Unfortunately we: cannot guess what you might be asking. Try rephrasing your question and asking again. It might be more efficient to consider an in-box consultation as more information can be transmitted and a discussion can occur between you and a provider. ...Read more

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My sgpt and sgot level are high 83 & 75 respectively. What should be my diet i m indian vegiterian person?

My sgpt and sgot level are high 83 & 75 respectively. What should be my diet i m indian vegiterian person?

Do you drink?: Your enzyme levels are only mildly elevated. If you take alcohol, stop for three months and retest. If you do not drink, you may wish to get tested for hepatitis virus infection. If all of these are negative, try a high protein diet and vitamin supplements. ...Read more

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My wife (28) is 33 week pregnant have elevated level of sgpt and sgot , is there any complications?

Liver enzymes: SGOT and SGPT are liver enzymes that can indicate liver cell lysis (rupture) when significantly elevated. Her OB MD is probably monitoring this condition which can occur in pregnancy when the gall bladder and bile system drainage is impaired. ...Read more

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I have fatty liver, diabetis and high sgpt and sgot levels...I am worried.watvshoukd I do?

I have fatty liver, diabetis and high sgpt and sgot levels...I am worried.watvshoukd I do?

Follow Doctor's: Instructions for diet, exercise, weight loss and medications. Your problem is treatable but will require your cooperation and effort to improve your health. Thanks for trusting HealthTap! ...Read more

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What will be the consequences of elevated sgpt and sgot levels?

Depends on cause: Elevated liver enzymes reflect liver cell injury and the consquences depend on the cause. It may due to self-limited viral infection, alochol intake, side effect of drugs, result of chronic hepatitis etc. See this site for more info.
http://www.mayoclinic.com/health/liver-problems/ds01133. ...Read more

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My sgot level is 64 and sgpt level is 84.i hv taken painkillers as had a minor accident and a typhoid medication.is the high levels is due to this.

Yes: The elevation in SGOT and SGPT are most likely due to acetaminophin containing pain killers, and not typhoid antibiotic therapy. Any history of Hepatitis, and comparison to previous SGOT/SGPT levels are most helpful in diagnosis. ...Read more

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I have elevated levels of ALT (sgpt) and AST (sgot). What does that mean?

Liver function tests: Alt and ast, prior noted as SGOT and sgpt, are part of a group of enzyme known as transaminases. They rise if something is inflaming the liver, such as a viral illness, mononucleosis, alcohol toxic effects, obesity or diabetes causing fatty infiltration in liver, adverse drug effects from a variety of medications... ...Read more

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Sir which high enzyme levels indicate significant liver damage due to alcohol? GGT levels or SGPT or SGOT levels.

SGOT / SGPT: These are better markers for damage. SGPT 38, SGOT 28 are not concerning though they're higher than most young men's. Some men run a high GGT even if they don't drink and this shouldn't be taken as proving anything. If you're drinking daily, this might be a good time to cut way back -- who really needs to be doing this? ...Read more

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74yr old, heart ejection fraction 40%. Hep c n liver cirohsis. Enzyme level high! Sgot is 169 n sgpt is 96. Albumin is 2.52. Pl advice?

74yr old, heart ejection fraction 40%. Hep c n liver cirohsis. Enzyme level high! Sgot is 169 n sgpt is 96. Albumin is 2.52. Pl advice?

What is the problem?: The numbers given need to have a context for evaluation; what symptoms do you have? Are these new fluctuations in the numbers, or are they stable? ...Read more

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What type of treatment is given to patients with elevated levels of sgot, sgpt and alkaline phosphatase?

Depends on the cause: We do not treat the tests but what is the reason for the abnormal tests
it may be due to gall bladder disease, or liver condition and the underlying condition has to be addressed and treated. ...Read more

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I have alkaline phosphatase elevated (450u/l) as well as (sgpt), (sgot), and ama test is positive, age 37y (woman), have anaemia and low level of iron?

Sort this out: You need to be told straight-up whether you are going to be diagnosed with & treated for primary biliary cirrhosis. If you also have iron deficiency anemia, the cause needs to be found. I hope you are not a non-supplementing vegetarian & that a search for possible sources of blood loss is underway. Be proactive & insist on answers. Good luck. ...Read more

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Is salmon omega 3 capsules useful in elevated sgpt, sgot, bilirubin's and triglyceride levels?

Don't treat labs: Omega-3's have been a massive disappointment in most areas when subjected to scientific testing. Most important is finding WHY these liver tests are up. If its chronic hepatitis B or C, hemochromatosis, Wilson's, or autoimmune hepatitis, you're going to die if you're not diagnosed & Rx'd. If this is non-alcoholic steatohepatitis, nothing will help as much as getting aerobically fit. ...Read more

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Are sgot and sgpt levels helpful in diagnosis of hep c. How do they alter in hep c?

Are sgot and sgpt levels helpful in diagnosis of hep c. How do they alter in hep c?

Yes: Usually they are up in hepatitis c, both acute and chronic, and are typically the first warning. There are other causes of their being elevated. ...Read more

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I am 24 years old and 36 weeks pregnant and My Enzyme is high SGOT and SGPT is 147 and 133?

See your doc soon.: Probably benign, but could be serious. Need screening to eliminate routine culprits of Hepatitis A/B/C, fatty liver, autoimmune hepatitis, benign cholestasis, gallbladder and pancreatic disease. Most serious concern could be HELLP syndrome or preeclampsia. ...Read more

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My sgot and sgpt is high. I m not alcolic... Pecribe medicine?

Find cause: Your need to be worked up for chronic hepatitis b and c, hemochromatosis, autoimmune hepatitis, wilson's, and non-alcoholic fatty liver. Every one of these can kill you if neglected but is manageable. Treat the cause, not the lab value. ...Read more

Sgpt (Definition)

Liver enzyme that has a metabolic function, its elevated when ...Read more


Sgot (Definition)

Has metabolic function, elevated if ...Read more