Doctor insights on:
High Igm And High Esr
I am being tested for Lupus my APTT ratio was 1.16 slightly raised and my cardiolipin IGM was 102ug/l ESR raised but ANA was normal.
Need more data: This will depend on more information that I have at this point. Then ANA could be negative if only a binding essay was used rather than an immunofluorescent assay. You may fulfill criteria for lupus anticoagulant. You will need to have your physician clarify these tests which Lab did them and how accurate they are. ...Read more
72mg/l urine protein then came back 60mg/l (not 24hr) gp refusing to do a 24hr collection or ultrasound! IgM 133/ IgA 4.86/crp12.86, mchc 310/esr 23.
Lab data: Without a full history, physical exam and all labs cannot possibly provide further advice about this. Labs without a clinical basis for assessment are seldom of much value. ...Read more
This is my first pregnancy. Found rubella igg-55 iu/ml and igm-10 and ESR -27 mm/hr and pcv - 34.50%, mch-25.70 pg, mcv-75.80 fl, rdw-16.80%.?
Low C3 level, low hct, little low red blood count, everything else is normal (c4, iga, igb, igm, esr, ssa, ssb, ana, urinalysis) what could this be?
Why the tests?: You need to give some history on yourself since no lab test can truly diagnose a disease. Anemia appears to be the most important issue and with the low C3, you may possibly have an autoimmune type of hemolytic anemia. However this is an open issue and you should consult a hematologist to do further testing. ...Read more
72mg/l urine protein normal? I thought any protein in the urine was bad! IgM 133u/ml IgA 4.86g/l CRP 12.86, mchc 310g/l ESR 23 recurrent uti's &fatigue
Not true: 24 hour urine protein up to 150 mg is normal. ...Read more
72mg/l urine protein is this normal? (not a 24hr sample) IgM 133u/ml IgA 4.86g/l CRP 12.86, mchc 310g/l ESR 23 chest pain + recurrent uti's &fatigue
High white cell?: Low IgM per se is unlikely to be of major clinical importance but a persistently high WBC requires further evaluation by a hematologist in the absence of an acute or chronic infection. On the other hand, a transiently elevated WBC (no more than a week duration) is likely from an acute infection be it viral or bacterial. ...Read more
Probably nothing: Elevated IgM can be a sign if hyper IgM syndrome an immunodeficient disease. Howerver most elevations are inconsequential. ...Read more
EB VCA IGM < 36 (0-35.9 range), EB EA IGG < 9 (0-8.9 range), EB VCA IGG 300 (0-17.9 range), EB NUC AGAB IGG 454 (0.0-17.9 range). last 2 too high?
Can rnp:1.6 (normal<1.0) be from high vcaigg? My u1rnp is >0.2 and all ena- panel >0.2. My ebna:0.8, vca-igm:<0.2, ea-d:0, vca-igg:5.8 (normal >1.0).
See below: More than likely this will be a false positive lab. When in doubt consult with a rheumatologist. ...Read more
My PT result is 7.4 secs, it says normal is 9.5-13.5 secs. IgM below base level. Very High Eosiphils count GP said ALL no consequence. Any ideas2 help?
See allergist: Very high eosinophil count (>1500) when persistent may cause organ damages and even death depending on the cause. If this is a one time finding, get the test repeated in 30 days and see if these abnormalities persist. If yes, then consult an allergist. If you had recently traveled to a developing country, parasite is one thing to rule out. ...Read more
It depends: It depends on how high the level is. Normal igm levels vary depending on age. A high igm level at one age may be normal at another age. If the level is borderline elevated I would not be concerned. If it is 5 times the upper limit of normal then I would go to a hematologist. ...Read more
IgM levels: Elevated IgM levels to what?? Igm elevation usually means an active infection or a recent immunization. These levels are specific, though. For instance, if you contracted measles, the IgM level to measles rises over the first few weeks, and then usually disappears by 6-8 weeks after illness. So if child had shots or was recently sick, I'd want to see IgM levels rise for that specifically ...Read more
Remote infection: Igm is the first class of antibody made to a microbe and after several months the immune system starts to make igg class of antibodies and then the immune system stops making igm. If all that is found is igg to a particular microbe it means that you were infected over about 6 months to many years previously. ...Read more
Blood Clots too much: Beta-2 glycoprotein 1 antibody tests are used to help find the cause of unexplained blood clots (thrombotic episodes) or recurrent miscarriages. Also used to diagnose antiphospholipid syndrome (APS), or to detect the autoantibodies in someone with another autoimmune disorder. Sometimes may be ordered with cardiolipin antibody and lupus anticoagulant testing. IgG, IgM or IgA may be elevated. ...Read more
Can't tell: Isolated labs are not how doctors make diagnoses. History is the most important part of a medical evaluation. Why were the labs performed? The mpv is a measure of average platelet size; it is only meaningful if platelets are decreased. Mildly elevated igm levels can indicate infection or immune dysregulation. The RDW and MCHC are red blood cell properties. Many healthy people have these results. ...Read more
I have cmv with igg =500, igm = 1.02, avidity = 90% (high avidity) with this shall I try for a baby?
Yes: Your IgG level indicates a remote infection and your IgM level is low indicating no recent infection. All the best. ...Read more
Dr said I had mono this summer. Igg was 4.44 which still showed high. Early IgM was o.28 and nuclear was 8.43. By aug my IgG IgM increased?
Mono and antibodies: Check with your doctor to ensure you are no longer in the active phase. Usually the igm levels are high then the igg levels will rise showing that you no longer are in the active phase. Good luck. ...Read more
Depends: The "normal ranges" for all lab tests include 95% of the "normal" population; thus, 2.5% of people are above the upper limit, and 2.5% are below the lower limit. There's nothing to worry about if your values are a little bit above the normal range, but a very elevated IgM could be a sign of a problem. You need to check with the physician who ordered the tests to interpret your results. ...Read more
Antiphospholipids: Autoimmune antibodies can be formed against natural (normal) cell surface proteins. When this happens, adverse effects can occur. Anti-cardiolipin antibodies have been associated with abnormal blood clotting events and recurrent spontaneous miscarrages. See a hematology specialist for advice on this problem. ...Read more
OskarD071: This means that you have allergic tendencies but it doesn't tell you to what. ...Read more
I have trouble interpreting HSV 1.2 Combo test. Super worried. Negative for IgM but super high positive 185.8 for IgG?
Means past infection: A person whose lab test result says HSV IgG positive means the person had caught HSV sometime in the past, but there is no way to tell exactly how far back in the past. The positive result does not tell which part of the body is involved in the infection, because HSV affecting any part of the body will give a positive test result. The majority of adults have Herpes type 1 and are positive for HSV. ...Read more
My t-igm is positive and t-igg is negative? What does that signify? And what's the reason for wbcs being high? Any further tests?
Phases of infection: Igm is the antibody that is 1st to rev up in early phases of infection. Then as the body begins to fight infection it produces more igg antibodies. The body keeps igg around as a "memory" so it can respond more quickly and vigorously if it sees that infection again. The duration and efficacy of the memory is variable. This is also how vaccinations work. ...Read more