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Doctor insights on: High Hcg Levels Down Syndrome

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Why are high hCG levels an indicator of down syndrome?

Why are high hCG levels an indicator of down syndrome?

See below: As tests were developed to assess the fetal health it was noted that a fetus with down's syndrome had higher maternal HCG levels that a normal child. This came to be part of the test, along with maternal age and ultrasound examination, to asses the risk of having a down's child. ...Read more

Dr. Tonya Kozminski
448 Doctors shared insights

Hcg Level (Definition)

Beta-HCG is a pregnancy hormone. It is expected to double every 2 days in a normal pregnancy. If the level rises too slowly, it may indicate an ectopic pregnancy. If it drops, it usually means ...Read more


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My LMP is 27apr14 and my beta hCG level on 28may14 found 6805.93mIU/mL and on 30may14 is 14798.49mIU/mL. Is it normal or doubt of down syndrome?

My LMP is 27apr14 and my beta hCG level on 28may14 found 6805.93mIU/mL and on 30may14 is 14798.49mIU/mL. Is it normal or doubt of down syndrome?

Normal: Your HCG levels have appropriately doubled. It is a good sign of a healthy pregnancy. If you are concerned about Down's syndrome, please speak with your doctor regarding early blood tests that will help with diagnosing an abnormal pregnancy like integrated screening or verifi prenatal test. Good Luck! ...Read more

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Could high levels of hCG point to down syndrome? Mine were around 245, 000 at 9.2 weeks. Have had ultrasound and only one baby.

Could high levels of hCG point to down syndrome? Mine were around 245, 000 at 9.2 weeks. Have had ultrasound and only one baby.

Range for normal HCG: Levels at 9-12 weeks LMP is 25, 700 – 288, 000 miu/ml, so yours is ok. At 11-14 weeks, a skilled ultrasonographer can determine if there is increased fluid under the skin at the base of the fetus' neck, a sign that other screens or diagnostic tests for ds are neeeded. A "quad" test that measures 4 pregnancy hormones screens for increased risk of certain birth defects including ds at 16-18 weeks. ...Read more

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Is high hCG in early pregnancy (5-6 weeks) and indicator of down syndrome?

Is high hCG in early pregnancy (5-6 weeks) and indicator of down syndrome?

Discuss w/ Dr.: How high? What specifics? Discuss these concerns w/ your OBGYN. I've heard that the increased risk is specifically about a small portion of the hCG called the beta subunit. If that is high, they consider it an increased risk for Down Syndrome. It's not so much a concern early in pregnancy - they usually test for this between 15-18 weeks and it's part of the quad-screening test. I hope this helps. ...Read more

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5w4d pregnant Hcg at 14031 (up from 5859 in 48h). Are these normal values or is there risk for Down syndrome?

5w4d pregnant Hcg at 14031 (up from 5859 in 48h). Are these normal values or is there risk for Down syndrome?

More likely two: That is higher than average, but that's not unusual either. It is much more likely to mean twins than Down Syndrome. See your OBGYN to evaluate this and ask about how to understand your lab results overall. Congratulations and best wishes! ...Read more

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My hcg level was 8, 649 at 4 weeks. Is this high?

My hcg level was 8, 649 at 4 weeks. Is this high?

Does not seem high: Your blood betaHCG levels rise very rapidly during early. They will usually double every 48 to 50 hours and their fluctuation may be affected by the sex of your fetus and by your ethnicity, your age, your body weight and other factors. ...Read more

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What could be the reason behind having high HCG levels?

What could be the reason behind having high HCG levels?

HCG: Human Chorionic Gonadotropin is a hormone that normally supports the development of the egg in the ovary, its release and then helps support pregnancy. However, some abnormal tissues can also produce this hormone or one very similar to it. Most pregnancy tests are based on this hormone. It use as a tumor marker requires a different setting and test system. ...Read more

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@ 8 weeks with high hcg levels will a preg test definitely come out positive?

@ 8 weeks with high hcg levels will a preg test definitely come out positive?

Yes: Urine pregnancy test usually comes positive with much lower hcg levels at the start of pregnancy ...Read more

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Can you have high HCG levels after you miscarry and should I worry about this?

Can you have high HCG levels after you miscarry and should I worry about this?

Consult doctor: HCG should rapidly fall after a miscarriage. If HCG persists it likely means retained products, a new pregnancy and uncommonly, tumor of chorionic tissue. Please consult your doctor for an evaluation and appropriate action. ...Read more

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Are you HCG levels normal or could it possibly be multiples? At 8dpo =13, 10dpo =57, 16dpo =1195 & 18dpo=2628. Numbers are high and doubling fast.

Are you HCG levels normal or could it possibly be multiples? At 8dpo =13, 10dpo =57, 16dpo =1195 & 18dpo=2628. Numbers are high and doubling fast.

Ultrasound: There is wide variation on HCG levels in normal pregnancies for the levels to be reliable indicators of multiple embryos. Examination by ultrasound would be more reliable. See this site for HCG levels.

http://www. Babymed. Com/hcg-level-in-early-pregnancy ...Read more

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Dpo/hcg levels: 14=233; 15=389; 16=683; 19=2821; 21=4643; 22=6533; 24=9596 (86 hrs doub. Time). Can high early hCG = earlier decline in doubling time?

Dpo/hcg levels: 14=233; 15=389; 16=683; 19=2821; 21=4643; 22=6533; 24=9596 (86 hrs doub. Time). Can high early hCG = earlier decline in doubling time?

Not really!: The 'doubling time' is not strict, it's a rough guide. Normal pregnancies may only go up by 2/3 in 2 days not 'twice.' furthermore each level is accurate to about +/- 15%, they are not 100%. Your numbers look normal, I wouldn't wear out your calculator doing this kind of thing. ...Read more

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My HCG level was at 1621 on Sept 18. Is it possible for it to be that high if I had sex on Sept 2? I also had sex with another partner on Aug 24 & 27

My HCG level was at 1621 on Sept 18. Is it possible for it to be that high if I had sex on Sept 2? I also had sex with another partner on Aug 24 & 27

Yes.: Yes, it's possible. If you ovulated at the time of having sex on sept. 2, then fertilization (pregnancy) may have occured shortly thereafter. ...Read more

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Can you have a fantom pregnancy? And would ur blood detect high hCG levels if ur having a fantom pregnancy?

Can you have a fantom pregnancy? And would ur blood detect high hCG levels if ur having a fantom pregnancy?

Phantom Pregnancy: Yes, this rare event is possible. There would be no HCG levels if there is a phantom pregnancy. ...Read more

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5 weeks pregnant hCG levels at 6500 is that to high for 5 weeks?

5 weeks pregnant hCG levels at 6500 is that to high for 5 weeks?

No: In early pregnancy, HCG levels are highly variable. A level of 6500 would be quite normal. Best wishes! ...Read more

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What are the causes of a high hCG level?

What are the causes of a high hCG level?

Pregnancy or tumor: Hcg is the normal hormonal product of the placenta and so levels are high in pregnancy; a urine pregnancy test looks for hcg. However some tumors also produce hcg, so a high level in a man, or in a non-pregnant woman, strongly suggests a tumor that needs to be found and treated as soon as possible. ...Read more

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Fri Hcg level 18000. Mon 28000. Wed 38000. Just turned 6wks on Tue. My Dr is concerned its not high enough, what do you think?

Concerned: In a normal early pregnancy the HCG level should have doubled between Friday and Monday. I'm sure that is why your doctor repeated it on Wednesday and it still did not rise as much as would be expected. I would want an ultrasound to be sure the baby is in your uterus and not in a tube and that everything looks ok. This could still be a normal pregnancy but I am concerned. Good luck. ...Read more

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Is 1772 high hCG level for 17 dpo?

Well....: It is hard to make a judgment based on one isolated hormone level. BHCG levels vary widely from person to person. It's better to follow a trend by checking a second level a few days later. That gives you more information. ...Read more

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Are high hCG levels cause for concern?

Are high hCG levels cause for concern?

Yes: Hcg levels can vary significantly in different pregnancies at different times of preg. Extremly high levels can indicate other disease processes like gestational
trophoplastc disease. The value needs to be weighed in view of the whole clinical picture. This would be best evaluated by a board certified obgyn. ...Read more

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What can I take (meds), or do for my hCG levels to become high?

Nothing: The health of the pregnancy and its stage determine the level of HCG and neither you or your provider can usually make a difference in that regard. ...Read more

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Hi, I had my hCG levels done on weds and they came back 7800 ithen on mon and they were 22000. Is this to high for 4-5 weeks?

Hi, I had my hCG levels done on weds and they came back 7800 ithen on mon and they were 22000. Is this to high for 4-5 weeks?

Wide normal levels: There a wide range of normal HCG levels during normal pregnancy and it may be reasonable to repeat the test if there are any concerns. See this site for the range of normals.
http://www. Americanpregnancy. Org/duringpregnancy/hcglevels. Html. ...Read more

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Roughly 7wks preg. Yesterday's hCG level was a little over 118, 000. Today (23hrs later) 132, 000. Too high for 7weeks? Multiples? Further along?

Roughly 7wks preg. Yesterday's hCG level was a little over 118, 000. Today (23hrs later) 132, 000. Too high for 7weeks? Multiples? Further along?

No worries...: This varies amongst women. A normal level at 7 weeks is anywhere between 7, 650 to 229, 000. As long as you're having an appropriate rise in your HCG level (doubling every 48-72 hrs), then there's nothing to worry about. If you want to find out how far along, or if multiples, it's better to get an ultrasound. Make an appointment with your OB ASAP. Congrats on your pregnancy! ...Read more

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Hcg levels at 4 weeks 4 days where 1300 does this seem like a high number I know its hard to tell from a single test waiting on results of 2nd test?

Hcg levels at 4 weeks 4 days where 1300 does this seem like a high number I know its hard to tell from a single test waiting on results of 2nd test?

HSG Levels: Hcg levels rise throughout the pregnancy. I assume you are saying 4 weeks 4 days from the last menses. The levels of HCG double approximately every 48 hours. Therefore, the level may be normal. Sometimes a "high" level may indicate multiple pregnancy, getting the dates wrong or a normal pregnancy. I would get an ultrasound at 5 weeks assess the pregnancy. ...Read more

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Is hcg level 26 days after sex high enough to have an accurate hpt?

Is hcg level 26 days after sex high enough to have an accurate hpt?

Border line: HCG level of 25 is generally diagnostic of pregnancy. 26 is at the borderline and you may wish to wait 2-3 days to do hpt. Use first morning urine and follow the instructions for the test carefully.
Get HPV vaccine. ...Read more

Dr. Kathryn Akin
654 Doctors shared insights

Down Syndrome (Definition)

A genetic chromosome 21 disorder causing ...Read more