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Doctor insights on: High Grade Spindle Cell Sarcoma

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Help please! is chemotherapy effective on high grade spindle cell sarcoma?

Help please! is chemotherapy effective on high grade spindle cell sarcoma?

Yes it often is: Spindle cell cancers are often called sarcomas. They can arise either in the soft tissues or in the bones. Ask your doctor what is the name of your cancer? If it is a sarcoma, chemotherapy is useful in about half of the cases, often it is used in conjunction with surgery and radiotherapy. ...Read more

Dr. Creighton Wright
2 doctors shared insights

Sarcoma (Definition)

By definition, it is malignant (i.e., being locally invasive and at least theoreticlally capable of metastasizing), and arises from / mimics muscle or connective tissue elements that are not marrow or immune / white cells. The sarcomas are a tremendously varied and troublesome family of tumors, though thankfully less common than carcinomas and the leukemia / ...Read more


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I wanted to know is chemotherapy effective on high grade spindle cell sarcoma?

I wanted to know is chemotherapy effective on high grade spindle cell sarcoma?

Some help: High grade spindle cell sarcomas are aggressive and every effort to remove the primary, control the surgical site if larger than 10 cm with RT should be made. If metastatic foci are noted surgical resection can also benefit as seen with lung mets. Primary treatment with drugs like Ifosfamide and platinum may help but primary removal is most important ...Read more

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How fast does a spindle cell sarcoma grow?

How fast does a spindle cell sarcoma grow?

Lots of variety.: The term "spindle cell" sarcoma is a generic descriptive term that doesn't really give enough information. It would be like asking, "i saw a convertible, how fast can it go?" additional testing often reveals exactly what kind of sarcoma, and then once you know that, you can more accurately discuss the prognosis and the treatment. ...Read more

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What is prognosis for high grade abdominal sarcoma ?

Depends: This will depend in the size of the tumor, was it resectable? Even if it was radiation is needed for high grade tumors. Even with the best case features these are aggressive and can recur or spread. So prognosis will depend on every factor i asked about including whether there has already been any spread of the sarcoma. ...Read more

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My 29 year old was daughter was diagnosis with high grade undifferentiated sarcoma primary site lung 13.9 CM mass removed in nov . What is her prognosis?

My 29 year old was daughter was diagnosis with high grade undifferentiated sarcoma primary site lung 13.9 CM mass removed in nov . What is her prognosis?

Variable: It depends on her stage of disease that i assume was early and her sarcoma had not metastasized and hence she had surgery. She will need oncological follow up and chemotherapy may be indicated. Please see an oncologist and discuss pathology reports with them. ...Read more

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Does the presence of spindle cells in a pap smear always indicate cancer or can they be present with moderate or severe dyskariosis? Ie cin3?

Does the presence of spindle cells in a pap smear always indicate cancer or can they be present with moderate or severe dyskariosis? Ie cin3?

Not always cancer: Spindle cells (sc) have bilateral tapering poles (like a football); their presence on pap smear indicates issues ranging from benign reactive or reparative changes, artifactual/normal squamous cell shape, to rare malignancies (carcinosarcoma, metastatic desmoplastic melanoma). Sc morphology is seen in connective tissue. Pap grade (high or low intraepithelial lesions, cin 1-3) is more tellig.N. ...Read more

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What does soft cell sarcoma feel like?

What does soft cell sarcoma feel like?

Often no symptoms: You may have no symptoms other than a soft tissue mass. ...Read more

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Can you tell me some odd cells that were on the tumorthey called it sarcoma. What is going to happen next?

Need more info: It depends on many factors. First, is it a sarcoma of bone or soft tissue. Bone sarcomas usually get chemo, while it is variable for soft tissue sarcomas. It also depends if the tumor had spread. In most cases sarcoma is treated with surgery. Talk to your doctor to get more answers. ...Read more

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What's the success rate for stem cell transplants in advanced stages of ewings sarcoma?

Clinical trials...: The largest published study to date (one institution) showed no increase in survival over conventional chemotherapy. However, this question is currently being evaluated in a collaborative clinical trial between europe and the us. See: http://www.Cancer.Gov/clinicaltrials/search/view?Version=healthprofessional&cdrid=68608. ...Read more