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Doctor insights on: High Grade Sarcoma

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What is prognosis for high grade abdominal sarcoma?

What is prognosis for high grade abdominal sarcoma?

Depends: This will depend in the size of the tumor, was it resectable? Even if it was radiation is needed for high grade tumors. Even with the best case features these are aggressive and can recur or spread. So prognosis will depend on every factor I asked about including whether there has already been any spread of the sarcoma. ...Read more

Dr. Milroy Samuel
2 Doctors shared insights

Sarcoma (Definition)

By definition, it is malignant (i.e., being locally invasive and at least theoreticlally capable of metastasizing), and arises from / mimics muscle or connective tissue elements that are not marrow or immune / white cells. The sarcomas are a tremendously varied and troublesome family of tumors, though thankfully less common than carcinomas and the leukemia / ...Read more


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My 29 year old was daughter was diagnosis with high grade undifferentiated sarcoma primary site lung 13.9 CM mass removed in nov. What is her prognosis?

My 29 year old was daughter was diagnosis with high grade undifferentiated sarcoma primary site lung 13.9 CM mass removed in nov. What is her prognosis?

Variable: It depends on her stage of disease that I assume was early and her sarcoma had not metastasized and hence she had surgery.

She will need oncological follow up and chemotherapy may be indicated.

Please see an oncologist and discuss pathology reports with them. ...Read more

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Help please! Is chemotherapy effective on high grade spindle cell sarcoma?

Help please! Is chemotherapy effective on high grade spindle cell sarcoma?

Yes it often is: Spindle cell cancers are often called sarcomas. They can arise either in the soft tissues or in the bones. Ask your doctor what is the name of your cancer? If it is a sarcoma, chemotherapy is useful in about half of the cases, often it is used in conjunction with surgery and radiotherapy. ...Read more

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I wanted to know is chemotherapy effective on high grade spindle cell sarcoma?

Some help: High grade spindle cell sarcomas are aggressive and every effort to remove the primary, control the surgical site if larger than 10 cm with RT should be made. If metastatic foci are noted surgical resection can also benefit as seen with lung mets. Primary treatment with drugs like Ifosfamide and platinum may help but primary removal is most important ...Read more

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My dad died of sarcoma of the kidney do I have a high risk of it? And is it common?

My dad died of sarcoma of the kidney do I have a high risk of it? And is it common?

It is rare: Sarcomas are rare cancers. They typically do not run in the families. Yet the kidney tumors do run in families, sometimes. You need to verify if this was kidney cancer with sarcoma like change which is called Sarcomatoid Renal cell carcinoma. ...Read more

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What is sarcoma?

What is sarcoma?

Cancer: Sarcomas are cancers derived from "mesenchymal" tissues, generally referred to as bone and soft tissue. These differ from carcinomas that are derived from epithelial tissue. Sarcomas are less common and tend to behave differently than carcinomas. ...Read more

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What a sarcoma...

A cancer: Sarcomas are relatively uncommon tumors that arise from connective tissue. Sarcomas can arise from fat, muscle, cartilage, bone or bone marrow. They can show up just about anywhere. They tend to be slower growing tumors and often do not respond well to chemotherapy or radiation treatments. Surgery is often the first and best treatment for soft tissue sarcomas. ...Read more

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What is Ewing's sarcoma?

Adolescent bone Ca: Ewing sarcoma is a malignant bone tumor of childhood. It appears in adolescents between the ages of 10 and 20 years old. It is the second most common bone cancer after osteosarcoma originating mostly long and large bones.. Approximately 1 in 4 children will have metastatic disease at the time of diagnosis A five drug regimen of vincristine, doxorubicin, cyclophosphamide, ifosfamide, and etoposide is now most commonly used for treatment. ...Read more

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Can you die from sarcoma?

Yes: Left untreated, sarcomas eventually result in death. The length of time before death occurs depends upon the type of sarcoma, how rapidly it is progressing, the location of the sarcoma, the overall health of the patient, etc. ...Read more

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What is asteroid sarcoma?

Immediately: Seek out a 2nd opinion. I have not heard of that diagnosis. Sometimes inexperienced pathologists may make that diagnosis. If you have been given a diagnosis of sarcoma, it is imperative that you seek out a 2nd opinion from an expert pathologist in sarcoma. I have been trained in sarcoma from MD Anderson Cancer Center and offer free consults david. Stockman@orthopath. Com ...Read more

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What is asteroid sarcoma?

Osteosarcoma?: While "asteroid sarcoma" is not described in the medical or astronomy literature, it sounds a lot like osteosarcoma, so I presume that was the question. Osteosarcoma is a rare cancer of bones that usually occurs in teenagers. Treatment is with chemotherapy and surgery. In many cases, it can be cured, especially if it is caught before it spreads. Amputation is required only rarely. ...Read more

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Do a lot of people get sarcoma?

Do a lot of people get sarcoma?

Relatively rare: Sarcomas are a diverse and relatively rare group of malignant tumors that develop in soft tissue and bone. Soft tissue sarcomas form in fat, muscles, nerves, joints, blood vessels, and deep skin tissues. It is estimated that in 2011, approximately 10, 980 and 2, 810 americans will be diagnosed with soft tissue and bone sarcomas, respectively. ...Read more

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What is ewing's sarcoma exactly?

What is ewing's sarcoma exactly?

Rare cancer: It is a rare cancer which usually occurs in teenagers and young adults. It more commonly occurs in bones such as the thigh bone and pelvis, but can occur in other bones and soft tissues. The usual treatment is chemotherapy and surgical removal of tumor. Sometimes radiation is used in addition to or even instead of surgery if surgery would not remove entire tumor or would be to debilitating. ...Read more

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What to do if I have kaposis sarcoma?

Very good treatments: If you have KS, although there are specific medications for it, typically treating the underlying disease (AIDS) with take care of the KS. If you have been confirmed to have KS, you need to be under the treatment of an Infectious Diseases doctor or whoever handles HIV/AIDS in your area. ...Read more

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What does soft cell sarcoma feel like?

What does soft cell sarcoma feel like?

Often no symptoms: You may have no symptoms other than a soft tissue mass. ...Read more

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What are the tests for ewing's sarcoma?

Biopsy: The biopsy establishes the diagnosis. An MRI shows the local extent of the tumor. A ct of the chest show if it spread to the lungs. A bone scan will look if tumor spread to bone. Sometimes a pet ct is done instead. A bone marrow biopsy is done to see if tumor spread to the bone marrow. ...Read more

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Does sarcoma usually cause many symptoms?

Depends: It depends on the type of sarcoma, location of the lesion and stage of lesion. Sarcomas are cancers of the connective tissue, muscle and bone. ...Read more

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What are the symptoms of ewing's sarcoma?

Ewing's symptoms...: Symptoms can include:
pain and/or swelling, usually in the arms, legs, chest, back, or pelvis (area between the hips).
A lump in the arms, legs, chest, or pelvis. Fever for no known reason. A bone that breaks for no known reason. ...Read more

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Is it true that a sarcoma is a neoplasia?

Yes: Sarcoma is a rare type of cancer that arises from bones, muscles, nerves, fat and connective tissues in general. Neoplasia (or neoplasm) means formation of new tissue. As sarcoma, or any cancer, involves growth of new tissue, it is therefore a neoplasm. ...Read more

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Sarcoma can be derived from which tissues?

Sarcoma can be derived from which tissues?

Supportive tissues: Sarcomas fall into a group of malignancies derived from supportive tissue. Osseous sarcomas are derived from bone. The liposarcomas, fibrosarcomas, neurosarcomas have their origin in tissue excluding glandular components as in bowel, They can arise in any part of the body from H&N to retroperitoneum extremity and supportive tissue of stomach and uterus ie leiomyosarcoma ...Read more

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How to determine if I have kaposis sarcoma?

Examination: Usually one can tell just by examining the patient. If there is a question, a biopsy can be performed. Hope this helps. ...Read more

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What is the rate of recurrence for sarcoma?

What is the rate of recurrence for sarcoma?

It depends.: There are a wide variety of different sarcomas. The most important pieces of information regarding recurrence rates are if the sarcoma is "low grade" or "high grade" (also known as well vs. Poorly differentiated). Also, you should find out the exact kind of sarcoma. For example, is this liposarcoma, or is this a malignant peripheral nerve sheath tumor? Check with your surgeon or oncologist. ...Read more

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What is unspecified sarcoma? Is it serious?

Immediately: Seek out a 2nd opinion. Sometimes inexperienced pathologists make that diagnosis if they have not received proper training. If you have been given a diagnosis of sarcoma, it is imperative that you seek out a 2nd opinion from an expert pathologist in sarcoma. I have been trained in sarcoma from MD Anderson Cancer Center and offer free consults david. Stockman@orthopath. Com ...Read more

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What is unspecified sarcoma? Is it serious?

Yes: When a lesion is resected whether primary or metastatic and the composition appears to be ill defined but possibly adenocarcinoma, there may be a mixture of cells in the tumor mass, spindle in shape that stain with certain antibodies suggesting sarcomatous origin but with no specific primary noted. These are considered unspecified sarcomatous cells that may make the lesion more aggressive. ...Read more

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How do you treat recurrant Ewing's sarcoma?

Surgery, RT, chemo: When Ewing Sa metastasizes, most common site is lung. Once mets found cure is difficult. It may be necessary to treat the primary tumor with surgery and or RT, while the mets receive chemo. The current chemo regimen is a combination of drugs, doxorubicin, vincristine) cyclophosphamide and dactinomycin) Here combination chemotherapy has improved long term outcomes but not cures. ...Read more

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How common is it for somebody to get sarcoma?

Not common: Sarcomas are not very common, they can occur in the soft-tissue or bones and every year about 12000-15000 cases occur in the USA. ...Read more

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What are the most common symptoms of sarcoma?

Mass, sometimes pain: The most common finding is an enlarging mass. It is often non-tender but can be painful. But often there are really no symptoms other that the mass itself, . ...Read more

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Which type of tissue gives rise to a sarcoma?

Connective tissue: During development of a fetus, there are different layers, ectoderm, mesenchyme; mesenchymal tissue eventually forms bones, cartilage, fat, muscle, vascular tissue (blood vessels); so sarcoma arises from mesenchymal derived tissue and is named as such (bone-osteosarcoma; fat-liposarcoma etc); hope this helps;. ...Read more

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What are the major symptoms of ewing's sarcoma?

Pain and swelling: Ewing's sarcoma can arise from bones or soft tissues. In bones, ewing's presents with pain and usually a lump. In the soft tissues, there is a lump, but it is usually painless. Occasionally, patients may have fevers and chills. Not all sarcomas follow these rules, but these are the most common symptoms. ...Read more

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Do lots of people get sarcoma, or is it unusual?

Not too common: There are about 12, 000 new cases of soft tissue sarcoma every year in the US - so yes it is not a common cancer. ...Read more