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Doctor insights on: High Grade Dcis

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High grade DCIS 1mm removed successfully, pathology showed no spread, what chance of reoccurrence and what prognosis or need for follow up treatment?

High grade DCIS 1mm removed successfully, pathology showed no spread, what chance of reoccurrence and what prognosis or need for follow up treatment?

It depends on 3 fact: WE need to know the size of the DCIS, age of patient and recommendations of the doctor who has done surgery. There are 2 options of treatment once the tumor has been excised compeltely. Radiotherapy to the breast is commonly done in yourger(<60year olds) but can be spared in those over 75 year. Tamoxifen is another options proven to reduce the risk of recurrence. This is a curable condtion in 98% ...Read more

Dr. Jeffrey Stevens
55 doctors shared insights

Intraductal Carcinoma (Definition)

Intraductal carcinoma is a noninvasive condition in which abnormal cells are found in the lining of a breast duct. The abnormal cells have not spread outside the duct to other ...Read more


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Is it possible for breast high grade ductal carcinoma insitu (dcis) to spread to the major organs ?

Is it possible for breast  high grade ductal carcinoma insitu (dcis) to spread to the major organs  ?

Yes, though rare. : We know that a very small % of pts with high-grade dcis will have lymph node involvement, of which a smaller % can develop distant (metastatic) disease. ...Read more

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DCIS, left breast, biopsy itself removed high grade cancer cells, lumpectomy path 100% cancer free. Radiation necessary? What about proton therapy?

DCIS, left breast, biopsy itself removed high grade cancer cells, lumpectomy path 100% cancer free. Radiation necessary? What about proton therapy?

It depends: It may depend on your age. Radiotherapy to your involved breast may be required as it is the standard of care. Ask your doctor and let us know what advice you receive. Tamoxifen is another medication recommended after completion of Radiotherapy. ...Read more

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Cea .5.6 but thought to be elevated due to ovarien cysts, recheck 5 weeks after surgery ,its now 7.7,have history of dcis 4 years ago?

Cea .5.6 but thought to be elevated due to ovarien cysts, recheck 5 weeks after surgery ,its now 7.7,have history of dcis 4 years ago?

May still be normal: CEA cant be used for dx but only for monitoring the presence of a known malignancy with normal levels occassionaly reaching 10ugms. A normal value of CEA is a range from 0 to 2.5 (mcg/L). For a smoker, expected levels of CEA range from 0 to 5.0 (mcg/L). High levels may be an indication of cancer, but some will test high, even though they do not have cancer. ...Read more

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Lft and sgot was 42 - normal high being 38. Other liver enzymes are normal. Had dcis 7 years ago. Worried it spead to my liver? Retest 1 month.Scared

Unlikely dcis: Dcis is not invasive cancer. Would not expect it to go to liver (or anywhere else). Minimal to mild lft abnormalities - multiple causes, including meds, overweight, alcohol, fatty liver, other. If drinking, repeat test in 10-14 days of sobriety; if taking meds or supplements, check with doc and stop any that are not necessary. If necessary, minimal increase in got would not have to stop the drug. ...Read more

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I had 1mm of invasive dcis and had lumpectomy, mastectomy and 13 nodes removed, tamoxifen. High estrodial, then bi.Ooph & arimidex (anastrozole) is it excessive?

I had 1mm of invasive dcis  and had lumpectomy, mastectomy and 13 nodes removed, tamoxifen. High estrodial, then bi.Ooph & arimidex (anastrozole) is it excessive?

NO : Lots of information missing , the results of the tests. If I have to guess had initial lumpectomy , later mastectomy was done most likely due to recurrence , ovaries removed to control skeletal metastasis, if it is true it is usual correct pathway to control aggressive tumor in 53 yr old , not true provide additional info, speak to oncologist , good luck if all neg , seek ii nd opinion. ...Read more

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Throbbing headache at night, tired feeling, trouble sleeping, blurry vision at times, high bp, no interest in anythg. Diagnosed with DCIS in 2012.

Throbbing headache at night, tired feeling, trouble sleeping, blurry vision at times, high bp, no interest in anythg. Diagnosed with DCIS in 2012.

Depression, Anxiety: I understand your distress. “Throbbing headache, tired feeling, blurry vision at times” are likely due to High B.P. which can increase further with stress.. “trouble sleeping, no interest in anything” are likely due to anxiety and depression. See your Physician for High B.P and DCIS. See Psychiatrist for Therapy for stresses of relationships, separation, loneliness, insomnia and medical illness. ...Read more

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How fast does dcis spread?

Quite slowly: It is difficult to define. But it does not spread all that fast. You have a few months before you need to worry about that. ...Read more

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Why does dcis become invasive?

Why does dcis become invasive?

Unknown: If we knew the answer to this question, women with dcis would not all need surgery! about 50% of dcis (ductal carcinoma in situ), if left untreated, will go on to become invasive cancer. Certain genes in the dcis cells get "turned on", making them invasive, but we don't know what makes this switch happen. ...Read more

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How can I tell if I have dcis?

Cannot: Lcis and dcis are both conditions are variants of changes in the breast that can only be determined by biopsy. ...Read more

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