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Doctor insights on: High Ferritin Levels

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Dr. Richard Roberts
334 doctors shared insights

Ferritin (Definition)

Ferritin is protein complex that binds iron and controls iron levels inside all of our cells. Low levels in the serum is a useful marker of iron deficiency. Macrophages are cells that contain large amounts of ferritin, and this that helps them scavenge RBC at sites of old hemorrhage. High serum ferritin levels occurs from macrophage activation and is a ...Read more


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High ferritin levels indicates?

Iron overload or...: High ferritin levels in your thirties could be an indication of an primary ( hemachromatosis) or secondary (hemosiderosis) overload state, or chronic inflammation. Ferritin levels in the iron overload states are typically quite high and are typically > 800; whereas chronic inflammation will produce levels typically <800. ...Read more

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Can a very high ferritin level make your hb levels high too?

How high is high?: If you serum ferritin is well above the reference range, you have hemochromatosis until proved otherwise. If your personal physician does not know how to handle this, get with a competent hematologist or gastroenterologist. ...Read more

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Can IVF drugs cause high ferritin levels?

Can IVF drugs cause high ferritin levels?

Unclear question: What are ivf drugs? It would help to answer if you could spell out your concern. ...Read more

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Can a high ferritin level 647 ug/L (12-250) be caused by nonalcoholic steatohepatitis? How do you tell its not haemochromatosis?

Can a high ferritin level 647 ug/L (12-250) be caused by nonalcoholic steatohepatitis? How do you tell its not haemochromatosis?

Can do liver biopsy: Although blood testing (measurement of iron studies and HFE assay) combined with family history can be very suggestive, a liver biopsy with iron staining clinches a diagnosis of hemochromatosis and distinguishes it from other iron overload diseases. Sometimes ferritin is elevated as just an acute phase reactant. ...Read more

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My uncle on my moms side and my dads cousin both have a history of very high ferritin levels - i just got bloodwork back and my ferritin is very high?

My uncle on my moms side and my dads cousin both have a history of very high ferritin levels - i just got bloodwork back and my ferritin is very high?

See your doctor: to determine the cause. this can be due to multiple conditions including hemochromatosis. though ferritin is also an 'acute phase reactant' and can be high in infection and inflammatory processes ...Read more

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My husband is getting blood drained for high ferritin levels we were told this may be the reason we are not conceiving will our chances b improved now?

My husband is getting blood drained for high ferritin levels we were told this may be the reason we are not conceiving will our chances b improved now?

High ferritin: If the high ferritin is confirmed to be caused by hereditary hemochromatosis, then regular phlebotomy (discarding a portion of blood) will benefit most patients. Iron deposition can commonly cause disease in the liver, heart, pancreas and other organs, including the pituitary. Treatment may help reverse the effects of iron deposition, but not in all cases. ...Read more

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I have a high ferritin level. Could a very heavy period be your body trying to get rid of some iron?

I have a high ferritin level. Could a very heavy period be your body trying to get rid of some iron?

Maybe . . .: Ferritin is a protein your body uses to hold onto iron. Low ferritin suggests not enough iron, possibly leading to anemia. Too much ferritin might indicate iron overload or hemochromatosis. Heavy periods usually lead to anemia if you don't consume enough iron or produce enough blood to make up for difference. Best to follow up w/your family physician to check your blood count. ...Read more

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My mother has high ferritin levels in the4,000 she doesn't have hemochromatosis she is very worried her body aches and she doesn't feel good whatisit?

My mother has high ferritin levels in the4,000 she doesn't have hemochromatosis she is very worried her body aches and she doesn't feel good whatisit?

Hemochromatosis?: Blood test and family history may not be enough. Liver biopsy with iron staining may be needed to make a definitive diagnosis of hemochromatosis. Other possibilites of elevated serum ferritin are Liver disease, due to alcohol, viral hepatitis; chronic infections, hemolytic anemia, anorexia nervosa, and some drugs. ...Read more

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Do vitamin d, b-12 and high ferritin level have any connection with neuropathy in the leg and torso?

Do vitamin d, b-12 and high ferritin level have any connection with neuropathy in the leg and torso?

Multiple connections: Each of these might be connected to neuropathy- vit d deficiency increases risk of diabetes & auto-immune diseases including ms- these can cause neuropathy. B-12 deficiency often causes neuropathy. High ferritin can be caused by iron overload causing oxidative stress or can be caused by heavy alcohol use, liver disease & auto-immune conditions like sle, all of which may cause neuropathy. ...Read more

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Low serum iron 36 and very high ferritin level 1,171. Is this anemia of chronic disease? High liver enzymes and ALP 476. What's wrong?

Low serum iron 36 and very high ferritin level 1,171. Is this anemia of chronic disease? High liver enzymes and ALP 476. What's wrong?

Need more info: A complete history is needed! What other Med problems u have? The possibilities are many: anemia w elevated ferritin and normal MCV could be chronic disease. The elevated liver enzymes need imaging and if hep B and C were r/out, maybe a liver biopsy. Many chronic conditions like Rheumatoid arthritis,Lupus, autoimmune liver disease, may cause these findings. Did you mean Alfa fetoprotein?.see PCP ...Read more

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How high would ferritin levels be if they were elevated due to pancreatic cancer? Would they typically be above the norm?

How high would ferritin levels be if they were elevated due to pancreatic cancer? Would they typically be above the norm?

Not relevant: Ferritin levels reflect body stores of iron and may be elevated in many instances of inflammation. Ferritin levels are not a reliable indicator of pancreatic cancer. In fact there are not good blood tests for pancreatic cancer. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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High Serum Ferritin level,648ng/ml,found on routine test.I was taking iron supp for anemia,which I will stop now.Am I in trouble?Should I do anything?

Hi ferritin: High ferritin can indicate iron excess. You made the right decision. Ferritin usually reflects iron stores. High ferritin can occasionally reflect inflammation in your body. Are you ill or run down or inflamed? ...Read more

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Hi my iron ends up regularly high (184) but ferritin levels are always normal (40). Should I worry?

Not too high: You ferritin is not too high to worry about. It is a marker of inflammation and you should discuss it with your doctor at the next visit. You may consult this site for information in this topic: https://medlineplus.gov/ency/article/003490.htm ...Read more

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Iron serum high (180) yet ferritin levels low (113). Suffering symptoms akin to haemochromatosis. Can treatment (phlebotomy) be justified?

Iron serum high (180) yet ferritin levels low (113). Suffering symptoms akin to haemochromatosis.  Can treatment (phlebotomy) be justified?

Not necessarily: Serum iron levels are not a good test to make treatment decisions as it is very variable and do not reflect inappropriate iron deposition. Ferritin level is the standard. If there is a concern for hemachromatosis genetic test is available. If indicated, liver biopsy with iron studies can be considered. ...Read more

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My labs were Iron:197 with high TIbC and low ferritin levels what does this mean?

My labs were Iron:197 with high TIbC and low ferritin levels what does this mean?

Iron deficiency: Ferritin is an indicator of long term storage fo iron and the TIBC is the chemical in the blood that binds and transports iron. TIBC usually increases when total body iron stores are low but can also increase with hormone supplements or pregnancy. Iron supplements are recommended and are available OTC. They may color BM's black and cause some constipation, so stool softeners are helpful. ...Read more

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What is the optimal ferritin level before conceiving a baby? If you have a high risk patient with ferritin level of 7, will you let her wait or go?

What is the optimal ferritin level before conceiving a baby?  If you have a high risk patient with ferritin level of 7, will you let her wait or go?

Treat her: I'm not even a clinician and I know to do this. A proper workup for the cause of the iron deficiency would be in order as well. The question is not 'the best lab value', but 'Treat this serious deficiency and find the cause for the sake of this unfortunate woman.' ...Read more