Doctor insights on:
High C4 Complement Levels
Need values: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, it would have helped to know the actual values. It would be prudent to consult your doctor to rule out pre-diabetes or diabetes. ...Read more
Total complement activity (CH50, CH100) looks at the overall activity of the complement system. Typically, other tests that are more specific for the suspected disease are performed first. C3 and C4 are the most commonly measured complement components. A complement test may be used to monitor patients with an autoimmune disorder and to see if treatment for their condition is working. For example, patients with active lupus erythematosus may have lower-than-normal levels of the complement ...Read more
Iron overload or...: High ferritin levels in your thirties could be an indication of an primary ( hemachromatosis) or secondary (hemosiderosis) overload state, or chronic inflammation. Ferritin levels in the iron overload states are typically quite high and are typically > 800; whereas chronic inflammation will produce levels typically <800. ...Read more
Means nothing alone: Please forgive my frankness. This mishmash of lab results is meaningless apart from your history and physical exam. Reference ranges for labs are set so that a few percent of healthies fall outside on either end. If you feel well, ignore them. The high hs-CRP may be a heads-up that you've got more atherosclerosis than you think. If you feel well, ignore the rest. ...Read more
18m/o with high platelet (652), high mono, low neutrophil, high retic and high tsh? What do these mean?
Many possibilities: I dont know of a way to put all of those things together into 1 disorder. A high TSH implies that the thyroid level is low, but this needs to be checked as well as repeating the tsh. The other blood count abnormalities could be due to many possibilities. You would need to see a hematologist about it. ...Read more
Adnorm. Blood & cfs results: high: CSF protein-47, high cfs albumin-30.9; low total protein-5.7, low gamma globulin-.5, low IgG quantitative -621 worry?
CSF: Some experts consider CSF protein levels to be normal if the value is equal to or below your age in years. I don't think in your case there is a reason to worry. Other CSF components are important as well. Check with your physician to see if there is any reasons to worry. Hope you feel well soon. ...Read more
Chronic fatigue? Low TSH high beta globulins, high LFT, nuclear studies normal, all hormones normal. Any suggestions ?
Liver?: What did your doctor say about the high liver enzymes? It sounds to me like you need to be working closely with your doctor to figure out what is going on and what is best to do about it. I wish you the very best. ...Read more
Increased aldolase, complement c3/c4 serum, sed rate, c-react. Protein, beta globulin, monocytes, bun/creatin low mcv-mch, vit d-possible causes?
Complicated: When i was doing clinical medicine, these were collectively sort of the flags for sarcoid disease but I am not saying that's the case here. This is because sarcoid is a diagnosis of exclusion so the advice is to rule out other diseases with additional diagnostic tests which can be done by a primary care physician or rheumatologist. ...Read more
See MD immediately: Copper levels in the body are very tightly controlled. Excess levels can occur when elimination is reduced, such as Wilson's disease, or when there is excessive intact (deliberate or by accident). This can lead to neurologic, blood cell, liver, kidney and muscle damage. Elevation of CPK is often a sign of muscle damage. You must see a MD immediately to determine cause and possible treatment. ...Read more
Speak with your doc: It sounds as if your doctor is doing a diagnostic work up to include your parathyroic gland. If this is the case she may also order tests to visualize the gland as well as your bones. You may have had a recent fracture or problem that she is addressing. Hope you get to the bottom of it soon. ...Read more
Complement tests: The complement tests and c reactive protein test you mention are all nonspecific markers of inflammation. Many different conditions may cause elevations of these. So they can be due to autoimmune conditions, inflammation from cancer or numerous other disease states. It is also common for complement activation to be associated with low levels of c 4, due to consumption of it. ...Read more
May be, may be not: Further evaluation is obviously needed. I can't say whether it is related or not without getting more information. In many cases- probably those two are not related. However in a case of colon cancer with metastatic disease to the liver- it can cause both increase of bilirubin level as well as low iron. Go to see your md and discuss further your condition. ...Read more
Globulin level: 4.5, Albumin level: 3.9, Total Protein: 8.4, Albumin/Globulin Ratio: 0.9, AST: 68, ALT: 105. What do these levels mean?
Need med history: You need to tell us why was this test done. Did you have some complaints? Once we know your symtoms, if any, it is easier to interpret your lab results. Your liver enzymes are slightly high and so is the globulin level which can occur due to liver problems like Hepatitis. Your doctor needs to recheck these labs in another one or two months and find the cause?hepatitis? ...Read more
What condition(s) causes someone to have high total serum protein, high albumin, normal globulin and high total calcium levels?
Dehydration.: There are no diseases that specifically increase albumin. Therefore in order to get an elevated concentration there must be a decrease in the amount of water in the system. This would also account for the normal globulin. Calcium is bound to Albumin so that elevated Albumin will elevate your calcium levels as well. ...Read more
What do low platelet levels mean?
Platelet level of 116 low
wbc 3.6 low
lymphs 61% high
neutrophils 22% low
neutrophils (absolute) low
See below: This is one of those problems where a visit to your doctor is necessary to figure out what's going on. Only after a thorough evaluation, including examination and possibly labs and other tests, can your doctor correctly diagnose you and treat you effectively. ...Read moreSee 1 more doctor answer
High WBC, high Neut, low lymph, low K, high glucose, lowRBC, low creatine, high amylase, high AST, urine w/ protein & ketones. Treatment?
Based on the: above lab results, and without any clinical knowledge of patient symptoms and course of disease, I would have to say it's impossible to devise a plan of treatment. Please visit your healthcare provider or begin a Virtual Consult with one of our physicians to discuss diagnostic and treatment options. Thanks for trusting in HealthTap. ...Read more
What do high neurophils high sed rate low platelets low monocytes and low lymphocytes point towards?
Infection: Infection from any source could provide. Need to see physician who ordered blood work. ...Read more
Muscle breakdown: High CPK levels suggest high levels of muscle turnover, either from intensive exercise or generalized muscle breakdown. CPK is also broken down into something else called ck-mb; if this is elevated alone with normal cpk, it may suggest a heart attack with appropriate symptoms. ...Read more
The complement system is an important effector mechanism of both humoral and innate immunity. Its functions are to promote phagocytosis of microbes, to stimulate inflammation, and to induce lysis of these organisms. The system is highly complex and comprised of over 50 effector and regulatory molecules. It is activated via one of three pathways: antibody, lectin, or by ...Read more