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Doctor insights on: High Bilirubin Low Enzymes

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Gallstone, 31% EF, low total bilirubin, high anion gap, hx of elevated liver enzymes. Liver enzymes leveled out after taking hormones. Causes? Advice?

Gallstone, 31% EF, low total bilirubin, high anion gap, hx of elevated liver enzymes. Liver enzymes leveled out after taking hormones. Causes? Advice?

HF: You have complex issues. Why do you have HF and also the cause of liver disease? The AGMA is concerning and has to be worked up. Some of these conditions can be related. What hormones did you take? I have more questions than answers, more so because you have 2 organ dysfunction and a acid base disorder and they can be related. ...Read more

Bilirubin (Definition)

Bilirubin is the potentially toxic product of heme metabolism. It is formed by breakdown of heme present in hemoglobin, myoglobin, cytochromes, catalase, peroxidase and tryptophan pyrrolase. Eighty percent of the daily bilirubin production comes from hemoglobin. It requires conversion to a water-soluble form before elimination from the body by ...Read more


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What do high levels of the liver enzymes ALT and bilirubin indicate?

What do high levels of the liver enzymes ALT and bilirubin indicate?

Jaundice: Obstructive juandice. Check for haaepatitis or gall stones ...Read more

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My dad is a ckd stage 5 patient. He is on HD thrice a week. His recent tests show high bilirubin of 237 but enzymes r lower. What does this mean?

Needs evaluation: Bilirubin is not affected directly by kidney failure or dialysis. Various types of medication can cause elevation or a variety of liver and biliary tract (bile ducts) problems can cause elevation. A level of 237 (micro moles/liter not mg/dl) is high (normal is 2-17). Have him discuss with primary MD and kidney doctor further evaluation and possibly seeing a liver specialist. ...Read more

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Bilirubin has been high on and off for 2 years. Did have a fatty liver but enzymes are normal since June could they b high due to something serious?

Bilirubin has been high on and off for 2 years. Did have a fatty liver but enzymes are normal since June could they b high due to something serious?

Liver injury?: Elevated liver enzymes indicate liver cell injury (enzymes leak outside the injured cells). Fatty liver disease (steatosis) can become more active when some of the liver cells can no hold no more fat so they rupture and thus add an inflammatory component to the process (it becomes steato-hepatitis) ...Read more

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Bilirubin on 5/29 was 1.2 put on pravstatin on 5/29 liver enzymes ok. 7/15 liver enzymes 114 and 54 bilirubin 1.7 why was bilirubin high before meds?

Bilirubin on 5/29 was 1.2 put on pravstatin on 5/29 liver enzymes ok. 7/15 liver enzymes 114 and 54 bilirubin 1.7 why was bilirubin high before meds?

Concerning: A bilirubin of 1.2 total is normal in my book, but the rise to 1.7 with liver enzymes up as well is concerning for your being allergic to your new medication. Perhaps a different rx is in order. ...Read more

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I have fatty liver my enzymes are usually slightly elevated the past 2 mths they r normal but my bilirubin is still elevated was 1.2 has been for a yr?

Gilbert's: Hi. Your slightly elevated bilirubin is probably unrelated to fatty liver. Your bilirubin is probably mildly high because of an insignificant defect in bilirubin conjugation. Have your doc check total and conjugated bilirubin. With Gilbert's, total bili is high and conjugated bili is low. ...Read more

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I was told that my liver enzymes where too high, the blood count is 2136000, and my bilirubin count is 7.5. What does it all mean?

I was told that my liver enzymes where too high, the blood count is 2136000, and my bilirubin count is 7.5. What does it all mean?

Serious liver: Disease. This issue is not suitable for a 400 character answer. Please see your doctor for proper evaluation through history, physical examintion, imaging, lab tests and may be trial of treatment. ...Read more

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Healthy young man. Total bilirubin :23 umol/l (< 21umol/l); slightly high. Liver enzymes, fbc, renal, lipid etc are normal. Had 2 similar results. Why?

Gilbert's: The vast majority of folks like you have gilbert's non-disease. It's not a problem and the treatment (phenobarbital) will just turn a healthy man into a sick man. The entity to rule out, even if you're not anemic, is a mild hemoglobinopathy. ...Read more

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Total bilirubin 1.99 direct 0.28. Enzymes good were high due to pravastatin but normal that im off it. Rdw is 14.4 mvp 7.3 fatty liver bad gallbladder?

Total bilirubin 1.99 direct 0.28. Enzymes good were high due to pravastatin but normal that im off it. Rdw is 14.4 mvp 7.3 fatty liver bad gallbladder?

Not uncommon: You can safely be monitored. Check in with your doc in a month or two for repeat labs. If pain persists in right upper quadrant, an ultrasound will tell about gallstones. Ct scan and tech hida don't always show gallstones. In meantime, stay on low fat diet. ...Read more

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A 2 year old has fever for 7 days and was taken to the doctor on Thursday. The spleen was enlarged. All the labs were done and liver enzymes, bilirubin and WBC were high. The follow up is today and the spleen has returned to normal. The labs have to be re

A 2 year old has fever for 7 days and was taken to the doctor on Thursday. The spleen was enlarged. All the labs were done and liver enzymes, bilirubin and WBC were high. The follow up is today and the spleen has returned to normal. The labs have to be re

Yes but...: What was the predominant type of WBC present? Serial wbc's can give us reassurance that we are dealing with a virus, but there are still other more serious problems that need to be ruled out. Like hepatitis, sickle cell with crisis, even neoplastic processes. Please stay in touch with your doctor. ...Read more

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Elevated liver enzymes and bilirubin on and off for 7 months is this normal with fatty liver?

Elevated liver enzymes and bilirubin on and off for 7 months is this normal with fatty liver?

Probably: It's a given that fatty liver is not normal. I trust that additional concerns -- notably wilson's -- have been ruled out, and that you're taking steps, including aerobic fitness, to keep the fatty liver at bay. I'm glad you're keeping this under close watch and hope you'll stay proactive. ...Read more

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Chronic Elevated Total bilirubin (2.5) direct bilirubin (0.5) and indirect bilirubin (2.0). All other liver enzymes are normal. What causes this??

Sounds serious: Hello again Matt. If your direct bilirubin is actually 0.5 mg/dL now, then this is more than Gilbert's which I understand is diagnosed. If this is not a lab error, then I suspect you have cholestasis too for some reason and you deserve a workup by somebody who's good with liver disease. Actually, the alprazolam / Xanax you're taking occasionally causes this. You might start there. Best wishes. ...Read more

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Total bilirubin 2.5 (Elevated), Direct bilirubin 0.5 (Elevated), Indirect bilirubin 2.0 (Elevated) All other liver enzymes normal. What causes this?

Rerun test: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, you need to re do the tests in non-fasting state. With the exception of elevated direct bilirubin, the findings are consistent with Gilbert syndrome, which is not a disease. See this site for more info:
http://www. Mayoclinic. Org/diseases-conditions/gilberts-syndrome/basics/definition/con-20024904 ...Read more

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Can poor periphery circulation and capillary refill cause elevated bilirubin and liver enzyme levels?

Can poor periphery circulation and capillary refill cause elevated bilirubin and liver enzyme levels?

Not likely: Peripheral circulatory disturbance is not expected to cause liver disease. Do not use Acetaminophen if you have liver disease. Please consult your doctor for evaluation. ...Read more

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AST elevated (65), ALT elevated (50) and total bilirubin elevated (3.0). All other enzymes are normal. Is this significant??

AST elevated (65), ALT elevated (50) and total bilirubin elevated (3.0). All other enzymes are normal. Is this significant??

Elevated Bilirubin I: Elevated Bilirubin is concerning. Elevated AST and ALT are mild. You need to see liver specialist (Hepatologist)
and have more testing. ...Read more

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Liver enzymes elevated AST 50 ALT 78 bilirubin 1.2 us showed very little fat in liver. Could this be thyroid problems? They keep fluctuating.

Liver enzymes elevated AST 50 ALT 78 bilirubin 1.2 us showed very little fat in liver. Could this be thyroid problems? They keep fluctuating.

Very little fat?: You shouldn't have fat in your liver, period. This isn't thyroid disease; everybody's levels fluctuate. If you drink alcohol, you need to stop for a few weeks and get rechecked -- this could be your wake-up call. You'll need hepatitis b and c, medication effect, hemochromatosis, autoimmune hepatitis and wilson's ruled out. If you do have non-alcoholic fatty liver, aerobic fitness is a key. ...Read more

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What causes elevated bilirubin and liver enzymes after gallbladder removal with ERCP and stent placement after?

What causes elevated bilirubin and liver enzymes after gallbladder removal with ERCP and stent placement after?

ERCP: Many laboratory values can be elevated after manipulation of your biliary tract with ERCP and stent placement since it is an invasive procedure. Your laboratory values are all relative and your provider can trend them. The important thing is to have close followup with your gastroenterologist regarding these lab values and/or any new symptoms like abdominal pain or nausea/vomiting after ERCP. ...Read more

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High bilirubin of 237 but lower enzymes, gallbladder stones & was on TB medication earlier but not anymore. Age57 what is the treatment? How to reduce

Sorry....: Billirubin can not be 237. If 23.7......the cause may be INH (TB med) induced liver damage. Need to see PMD.....for full evaluation. ...Read more

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Had mild fatty liver for a yr elevated enzymes and bilirubin. Blood work has been normal for 6 mths. Ultrasound shows no fat does this mean it better?

Something missing...: Mild fatty liver does not cause elevated bili and if fatty liver was noted on US it will not often disappear in a year. Elevated bilirubin and your age suggest other causes (alcohol, pregnancy, Hepatitis B or C, Gilbert's, autoimmune hepatitis?) If you are seeing a gastroenterologist I feel comfortable with your explanation otherwise I would expect that the above conditions have been examined. ...Read more

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Been constipated for 2 weeks, used enema Sat. Had very small bm, have elevated liver enzymes and bilirubin in urine, ultrasound was normal. Now what?

Do this next: Are you on any meds? Get a thyroid check and porphyria screen. Drink plenty of water and read about fiber, consider a stool softener. Trust you have no toxic exposures (lead) or risk for Chagas. Colonoscopy may be in future. How much bilirubin in the urine? How high were the liver enzymes? Has the liver workup proceeded (hep B/ c / iron overload, Wilson's, antinuclear antibodies)? ...Read more

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8days boy sever birth asphyxia. Total bilirubin 58mg Diret bili 20mg. Lncreased liver enzymes low haemoglobin. Normal abdomenal ultrasound. What diagnosi?

Very concerning: Massive hepatic necrosis in a newborn can be from herpes, CMV, medications, perhaps shock, etc. I hope for a good outcome but wish you strength and courage whatever happens. ...Read more

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Is 1.6 mg/dl bilirubin level normal if all other liver enzyme are normal. No yellowness of skin. How to lower it?

Need investigation: You may wish to repeat the test to make sure the result is correct. Bilirubin of 1.6 is elevated and it can be due to many causes, some harmless and others requiring treatment. You need to see your doctor to rule out conditions that may require treatment. See this site for more info.

http://www. Nlm. Nih. Gov/medlineplus/ency/article/003479.htm. ...Read more

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For two years indirect bilirubin has ranged from (.9-1.7) direct from (.1-.4). Dr said gilbert's. Normal liver enzymes and u/s. Gilbert's?

Probably: Especially if you can relate the higher levels to times when you may not have been eating so much. I trust there's no evidence that anything else is wrong. ...Read more

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Hida scan shows 17% function @ 20 min. No pain during exam 4.3 m of technetium 99m of choletec. 1.5mcg of cck. Bilirubin is 1.5 enzymes good.

Hida scan shows 17% function @ 20 min. No pain during exam 4.3 m of technetium 99m of choletec. 1.5mcg of cck. Bilirubin is 1.5 enzymes good.

Not sure of results: Most laboratories determine ejection fraction, percentage of emptying at 30 or 60 minutes after injection of cck. I am not sure meaning of ejection fraction at 20 minutes. ...Read more

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Upper right quadrant pain bilirubin 2.8. Other liver enzymes raised 2-3 times normal. Any help?

Upper right quadrant pain bilirubin 2.8. Other liver enzymes raised 2-3 times normal. Any help?

See doctor: It is not feasible to provide a meaningful opinion without examining you and your symptoms warrant evaluation by a physician. You may have gall bladder disease. ...Read more

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Can bilirubin levels and liver enzymes be raised by a bad virus?

Can bilirubin levels and liver enzymes be raised by a bad virus?

Yes: This is fairly common. They might also have been raised by the medications a person takes for the virus. If checking baseline liver function, it is best to wait until the patient has recovered fully from a recent viral illness. ...Read more

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If my levels of bilirubin and urobilinogen in urine is normal, does this indicate a healthy liver? I'm having routine liver enzyme tests and nervous.

Liver enzymes: While it is encouraging that these urinary tests are normal, they are not enough to ensure that your liver is healthy by themselves. If your doctor recommended routine screening tests of your liver, the blood tests are the only way to go. I would not worry; the vast majority of the people having a routine screening have completely normal liver tests. Good luck. ...Read more

Enzyme (Definition)

An enzyme causes the transformation of a compoond to another compound. In living structures, it is the transformation of a protein to another form. An example is from an inactive state ...Read more