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Doctor insights on: High Antinuclear Antibody

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Is an antinuclear antibody blood test result of 1.32 low, medium, or high? Is it something to worry about?

Is an antinuclear antibody blood test result of 1.32 low, medium, or high?  Is it something to worry about?

If 1:320, high-ish: Anas are reported as a ratio of how dilute the serum is when the antibody is still detectable, and the lowest ratio reported is usually 1 to 40, written 1:40. Meaning if you dilute the serum 40 fold, you can still find antibody. The next reading is 1:80, then 1:160, then 1:320. The number you write looks like it could be 1:320. That's a significant amount and might cause symptoms. Make appt w doc. ...Read more

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


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What does a highly elevated antinuclear antibody result mean exactly? Does it mean sle?

What does a highly elevated antinuclear antibody result mean exactly? Does it mean sle?

Not necessarily: In addition to sle a positive ana(antinuclear antibody) can be seen in a number of medical conditions, secondary to certain medications, and in otherwise healthy individuals. Therefore a positive ANA does not necessarily indicate the presence of sle. ...Read more

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Does highly elevated antinuclear antibody result always mean systemic lupus erythematosus?

Does highly elevated antinuclear antibody result always mean systemic lupus erythematosus?

Not always: Unfortunately, there is no single laboratory test that absolutely rules in or out systemic lupus erythematosis (sle). Although a highly positive antinuclear antigen (ANA) is common in sle, diagnosis is based on a careful history, physical exam and laboratory evaluation. ...Read more

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What is an antinuclear antibody test used for?

What is an antinuclear antibody test used for?

Autoimmune disease: ANA (anti-nuclear antibody) is a blood test used by doctors that indicates the presence of an autoimmune condition in which the body's immune system is predisposed to recognize normal things in your body as foreign invaders that need to be attacked. The results are not specific for any particular disease if positive, but are a preliminary test, after which a range of possibilities are considered. ...Read more

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My antinuclear antibody test came back positive, how worried should I be?

ANA - not diagnostic: The ANA (anti-nuclear antibody) can be present for many reason. It is classically seen in sle, but most people was a + ANA do not have lupus or a connective tissue disease. You evaluation will help clarify why you have the + ANA and how it relates to your medical condition. ...Read more

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What is a "positive antinuclear antibody with a homogeneous staining pattern & a litre of 1 in 160" ... & should I worry ?

Rheumatologist: ANA is a screening test for collagen diseases like lupus. A titer of 1 to 160 is elevated but has to be interpreted along with your clinical history. It may not be significant in your case. A rheumatologist is best suited to determine its significance. ...Read more

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Is a antinuclear antibody blood a sensitive test?

Is a antinuclear antibody blood a sensitive test?

Yes: Yes, the ANA is sensitive in the case of lupus erythematosus meaning that if you have lupus, the ANA will be positive over 99% of the time (few false negatives). However, it is very non-specific meaning that if you have a positive ana, you may have lupus or some other disease or nothing at all (many false positives). ...Read more

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My ANA (antinuclear antibody) test came back positive, how worried should I be? Do normal people have this?

Many False +: ANA is a screening test for autoimmune disease. False + are common. False negatives are rare. Yes, normal ppl do have this appear + sometimes. The lab should also indicate how positive the test was: mildly or strongly. Follow up tests to the ANA (such as dsdna and complement among many others) can determine if this was a true positive or false positive. ...Read more

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What does a borderline antinuclear antibody test homogeneous pattern 1:80 and sedrate westergreen 51 mean?

Not Much.: Doesn't really mean much without a compatible clinical syndrome. First you need symptoms then you need a test to tell you if the symptoms are real. Getting a test first then looking for symptoms is bad practice, often confusing and frustrating. Your current lab results may be perfectly normal for you. ...Read more