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Doctor insights on: High Alt In Kidney Disease

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High ALT in the liver.

High ALT in the liver.

Liver is in trouble: The alt enzyme is one of the main liver enzymes used to monitor liver health. A high level is most likely represents a very stressed liver that may be in trouble. The source of the damage that is occurring in this liver needs to be identified soon so that resolving the problem can be undertaken. ...Read more

Kidney (Definition)

The kidneys are paired organs that lie on either side of the vertebral column. Part of their critical functions include the excretion of urine and removal of nitrogenous wastes products from the blood. They regulate acid-base, electrolyte, fluid balance and blood pressure. Through hormonal signals, the kidneys control the ...Read more


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Bun/creatinine ratio is very high in kidney infections?

Bun/creatinine ratio is very high in kidney infections?

Generally no: An elevated bun/creatinine ratio (>20) is usually suggestive of "dehydration" and improves with increased fluids. Unless the patient with a kidney infection is also fluid depleted (due to vomiting or diminished fluid intake), the bun/creatinine is not excessively elevated in this setting. ...Read more

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Can high levels of bilirubin alone cause liver failure in a metastic liver cancer pt?

Can high levels of bilirubin alone cause liver failure in a metastic liver cancer pt?

Let's reframe the ?: The issue isn't the amount of bilirubin causing problems with the liver. The liver is likely infiltrated with tumor mets and therefore is not able to process bilirubin. The elevated bilirubin can have multiple causes but is a symptom of the liver failure rather than the cause. It can also be a symptom of obstruction of the biliary system in the liver by tumor or simply inactivity (cholestasis). ...Read more

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My daughter has hydronephrosis. High platelet levels, high creatinine and bun levels, white blood cells in her urine. No reflux.Possible kidney disease?

My daughter has hydronephrosis. High platelet levels, high creatinine and bun levels, white blood cells in her urine. No reflux.Possible kidney disease?

Azotemia: Your daughter needs to be evaluated by both pediatric urologist & pediatric nephrologist. Repeat my previous advice that you need to take her a center which can provide these services and believe that would by ucla or la children's hospital or uc irvine medical center. They should be able to make a diagnosis and optimally advise regarding treatment. My sympathies this is a serious problem. ...Read more

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Is dehydration linked to kidney high creatinine?

Is dehydration linked to kidney high creatinine?

It can be. : Any situation that causes excessive loss of body fluids (vomiting, diarrhea, severe bleeding, fevers, heat exposure, certain medications, etc) can lead to reduction in the body's entire blood volume. When this happens, part of your body's natural response is to reduce blood flow to some of its organs including kidneys. This can lead to kidney injury which can be detected by a high creatinine. ...Read more

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Wilson disease?? Hospitalized with hypokalemic parlaysis, alt & ast elevated, bradycardia. Now hypoglycemic, high Uric acid urine and low T3 (liothyronine).

Wilson disease?? Hospitalized with hypokalemic parlaysis, alt & ast elevated, bradycardia. Now hypoglycemic, high Uric acid urine and low T3 (liothyronine).

Too complicated: Your health issues are too complicated to be properly addressed in this forum. It is imperative that you keep in touch with your doctor who has more information about your health. ...Read more

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Are low level kidney diseases and high protein diets connected?

Are low level kidney diseases and high protein diets connected?

See below: I am unclear about your question, but if you mean does high protein diet cause quicker deterioration of kidney function, then the answer is potentially yes. ...Read more

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Albumin is high and INR is low. liver disease?

Albumin is high and INR is low. liver disease?

Unlikely: Typically with liver disease both the albumin and INR are low. The liver is an organ that is response for packaging both proteins absorbed from the GI tract (albumin) and producing clotting factors (INR). A high INR and low bilirubin is usually associated with liver disease given difficulties producing these factors. A low INR is nothing to be worried about unless taking blood thinners. ...Read more

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Are high blood pressure and kidney disease related?

Are high blood pressure and kidney disease related?

Yes: Untreated high blood pressure may cause kidney disease and vice versa some kidney diseases could cause high blood pressure. ...Read more

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Is low functioning gallbladder with elevated liver enzymes of AST 77 ALT 142 contributed by a underlying disease? If so what diseases?

Is low functioning gallbladder with elevated liver enzymes of AST 77 ALT 142 contributed by a underlying disease? If so what diseases?

Liver disease: Isolated "low functioning gallbladder" without gallstones would not commonly cause elevation of ast/alt. This could indicated fatty liver condition, hepatitis exposure, medication causing liver inflammation, etc. See your doctor or a gastroenterologist for full liver evaluation. However, if you do have gallstones then that could be a cause of the blood test results. ...Read more

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Does high bilirubin level indicate liver disease?

Does high bilirubin level indicate liver disease?

Bilirubin: Gilbert syndrome (normal variant usually less than 4), gallstone obstruction (you'll be very sick), end stage liver disease (again very sick), pancreatic cancer (causing obstruction). Could be many things, go over results with doctor and gi. ...Read more

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My ultrasound said abnormal resistive index on r kidney suggesting medical renal disease or renal stenosis. My kidney blood levels were all low?

My ultrasound said abnormal resistive index on r kidney suggesting medical renal disease or renal stenosis. My kidney blood levels were all low?

High Resistive Index: I have two questions, why did your doctor order a resistive index on you? Do you have hypertension (BP) that is difficult to control? If you do not have any bp, then you likely do not have a renal artery stenosis (ras). If you do have bp, you may need a renal artery angiogram to see if your BP is caused by a ras. See a nephrologist for more answers. Good luck. ...Read more

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Elevated kidney enzymes with dibeates?

Elevated kidney enzymes with dibeates?

Kidney trouble: It is well known that diabetes can lead to significant complications in the organs where there are very small blood vessels, i.e. Your eyes, your kidneys, and your feet and hands. If you are not getting good blood sugars on your treatment regimen this will only get worse. I would wish for you a good relationship with your diabetes doctor and good treatment to control your blood sugars. ...Read more

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How and why is there an increase in urobilinogen levels in hepatocellular dysfunctions like alcoholic liver disease, cirrhosis and malignancy of liver?

How and why is there an increase in urobilinogen levels in hepatocellular dysfunctions like alcoholic liver disease, cirrhosis and malignancy of liver?

Obstruction: When the liver is prevented from doing it's job due to disease it shows itself through elevation of certain chemicals in the blood because it is being blocked by physical disruption of the anatomy and bile goes into the blood causing yellowing of the skin ( jaundice). ...Read more

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Do kidney stones cause an increase in serum amylase?

Do kidney stones cause an increase in serum amylase?

No.: Many other things can do this, but not kidney stones. ...Read more

Previous Kidney Disease (Definition)

Polycystic kidney disease is a kidney disorder passed down through families in which multiple cysts form on the kidneys, causing ...Read more


Sgpt (Definition)

Liver enzyme that has a metabolic function, its elevated when ...Read more