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Doctor insights on: Hereditary Spastic Paraparesis

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What is hereditary spastic paraparesis?

What is hereditary spastic paraparesis?

Rare condition: Progressive leg weakness and spasticity (tightness and catching of leg with flexion), caused by autosomal dominant and recessive or x-linked genetics, with usual slow progression and normal life span. Mri may demonstrate atrophy of brain and/or spinal cord. ...Read more

Dr. Al Hegab
5 doctors shared insights

Partial Paralysis Of Lower Limbs (Definition)

Paraparesis is a clinical finding in which an individual has weakness or spasticity (rigidity) of the lower ...Read more


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What can I do about my hereditary spastic paraparesis?

What can I do about my hereditary spastic paraparesis?

Treat the symptoms: If the process is stable, and not progressing, best to try anti-spasticity meds, such as baclofen, tizanidine, or even a pump. Botox injections, although off-label, might be useful. Acupuncture has promise. Splints, braces, exercises all may help. If legal in your state, medical marijuana may help, as the research from europe suggests benefit in the spasticity associated with ms. ...Read more

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What is the definition of hereditary spastic paraparesis?

What is the definition of hereditary spastic paraparesis?

Hereditary SP: Hsp, is a genetic disorder transmitted as autosomal dominant, meaning one of the parent has the disease in order to pass it to the offspring. It is a progressive spasticity in the legs , may be associated with hypertonic urinary incontinence, seizure, dementia, or peripheral neuropathy. ...Read more

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Any treatment for heriditary spastic paraparesis? Accompanied by sensory neuropathy?

Any treatment for heriditary spastic  paraparesis? Accompanied by sensory neuropathy?

Symptomatic treatmen: Hsp is a group of inherited disorders, often insidiously progressive and severe. There are no effective treatments to the underlying damage to the nerve axons so treatment is symptomatic. Baclofen, dantrolene and tinazidine may help with spasticity; oxybutinin with urinary urgency; gabapentin, Pregabalin and duloxetine for neuropathy. Vitamins, d, e and b6 may also help. Physical therapy also. ...Read more

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What is tropical spastic paraparesis?

Disorder of sp cord: A subacute condition with impairment of lower extremity >upper extremity function, sensory abnormalities, bladder functioning and girdling lumbar pain. About 80 % of patients with tsp have antibodies to htlv-1 (not aids virus..Htlv-3) the disorder and similar disorders were described in caribbean patients. ...Read more

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Paraparisis cause? Its also known as familiar spastic paraplegia?

Paraparisis cause? Its also known as familiar spastic paraplegia?

See below: Paraparesis is a milder form of paraplegia ( which should mean no movement in the lower extremities but is sometimes used synonymously) familial spastic paraplegia is a paraplegia with family history of unknown etiology and is diagnosed when all the other causes have been ruled out. ...Read more

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Can u treat hereditary spastic paralegia?

Can u treat hereditary spastic paralegia?

Yes and no: Hereditary spastic diplegia or paraplegia is a slowly progressive stiffening of the legs. Some progress more rapidly and need aggressive therapy and bracing and even surgery. More often it is very slow and can be be dealt with without braces or surgery but with appropriate therapy. There is no cure, but there is good management. ...Read more

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What is the definition of hereditary spastic paraplegia?

Genetic?: Hereditary spastic pareplegia is the name given to a mainly motor disability often in lower extremities slowly progressive with a geographical distribution.The condition often does not cause sensory or bladder problems and all tests including mri, CSF studies B12 levels etc are normal some of these cases have antibodies to htlv 1 viruses in the blood or cerebrospinal fluid. ...Read more

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What does it mean if the doctor diagonosed paraparesis?

Usually: Both legs are too weak to stand or walk, indicating most likely a spinal cord issue. The tone and function of sphincters may be affected. Paraplegia means absolute lack of tone, sometimes the next step. ...Read more